CAS: 574-19-6; 1-(2-Hydroxynaphthalen-1-yl)Ethanone

相似化合物

17056-93-8 711-79-5 5672-94-6

上下游产品

CAS号75-36-5 乙酰氯 | CAS号135-19-3 2-萘酚 | CAS号1523-11-1 乙酸-2-萘酯 | CAS号5672-94-6 2'-甲氧基-1'-萘乙酮 | CAS号506-96-7 乙酰溴 | CAS号93-04-9 2-萘甲醚 | CAS号122-79-2 乙酸苯酯 | CAS号1205-91-0 对二乙酰氧基苯 | CAS号64-19-7 冰醋酸 | CAS号78156-61-3 1-methyl-2-benz... | CAS号941-98-0 1-萘乙酮 | CAS号20009-28-3 2-(2-丙炔基氧代)萘 | CAS号22228-20-2 2-Naphthalenol,... | CAS号288-32-4 咪唑 | CAS号21568-13-8 1-methylbenzo[f... | CAS号28656-21-5 3-(4-methoxyphe... | CAS号6051-87-2 β-萘黄酮 | CAS号573-97-7 1-溴-2-萘酚 | CAS号135-19-3 2-萘酚 | CAS号35299-76-4 K 8291

乙酸-2-萘酯置于aluminum (Iii) Chloride体系中,用 氯苯 作为反应溶剂,化学反应 0.5H,以91%的收率获得产物1-乙酰基-2-萘酚
参考文献:新型手性联苯碘代烷促进β-酮酸酯和萘酚的不对称炔基化
标题:新型手性联苯碘代烷促进β-酮酸酯和萘酚的不对称炔基化
摘要:新的手性biphenylic的λ制备3种-Iodane试剂轴承转让炔基配体进行说明.这些试剂以高达68%的对映体过量(ee)将其碳基配体转移到β-酮酸酯上,最显着的是,可以使萘酚脱芳基烷基化,产率高达84% Ee.
DOI:10.1002/chem.201703238

专利信息

专利号:US-7638554-B2
优先权日:2002-04-18
标题 :Flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
发明人：WALEH NAHID; ZAVERI NURULAIN T
权利人:STANFORD RES INST INT
摘要:Compounds useful as chemotherapeutic, chemopreventive, and antiangiogenic agents are provided. The compounds are flavanoids, including flavanones, flavanols, and chalcones. The compounds have the structure of formula (I) n nwherein R 1 through R 3 and R 5 through R 11 are defined herein, and α, β and γ are optional bonds, providing that when α is absent, β is present, and when β is absent, α is present. When α is present, preferred R 4 moieties are selected from O, S, NH and CH 2 , and when α is absent, preferred R 4 groups are selected from OH, SH, NH 2 and CH 3 . When γ is present, the preferred R 5 substituent is O, while when γ is absent, the preferred R 5 substituent is OH. Pharmaceutical compositions are provided as well, as are methods of synthesis and use.

专利号:US-7329687-B2
优先权日:2002-04-18
标 题:Flavanoid compounds as chemotherapeutic, chemopreventive, and antiangiogenic agents
发明人：ZAVERI NURULAIN; CHAO WAN-RU
权利人:STANFORD RES INST INT
摘要:Compounds useful as chemotherapeutic, chemopreventive, and antiangiogenic agents are provided. The compounds are flavanoids, including flavanones, flavanols, and chalcones. The compounds have the structure of formula (I) n nwherein R 1 through R 3 and R 5 through R 11 are defined herein, and α, β, and γ are optional bonds, providing that when α is absent, β is present, and when β is absent, α is present. When α is present, preferred R 4 moieties are selected from O, S, NH and CH 2 , and when α is absent, preferred R 4 groups are selected from OH, SH, NH 2 and CH 3 . When γ is present, the preferred R 5 substituent is O, while when γ is absent, the preferred R 5 substituent is OH. Pharmaceutical compositions are provided as well, as are methods of synthesis and use.