CAS: 531-44-2; Scopolin
该化合物是一种自然形成的化学化合物,被归类为甘蓝,主要来自各种植物物种,特别是索拉纳塞埃家族的植物物种.Scopolin以其潜在的药理特性而著称,包括抗炎和抗氧化作用.该化合物的特征是能够进行水解,导致释放可显示生物活动的丙酮.Scopolin经常因其在传统医学中的作用及其潜在的治疗用途而接受研究.从物理性质来看,它通常是白色的对白的晶状粉,在极地溶剂中溶解,其分子重量相对较低.其稳定性可能受到光和pH等环境因素的影响.与许多天然化合物一样,目前正在进行进一步的研究,以充分阐明其在现代医学中的行动和潜在用途机制.
物理性质
MSDS等安全信息
上下游产品
CAS号85011-57-0 scopoletin 7-O-... | CAS号92-61-5 东莨菪内酯； 莨菪亭 | CAS号5328-37-0 L-阿拉伯糖 | CAS号1207857-19-9 eryciboside A | CAS号92-61-5 东莨菪内酯； 莨菪亭 | CAS号492-61-5 β-D-葡萄糖 | CAS号2280-44-6 D-glucopyranose合成工艺路线路线简述
📜7-O-[6-O-(5-O-Syringoyl-β-D-Apiofuranosyl)-β-D-Glucopyranosyl]-6-Methoxycoumarin置于盐酸,水体系中,化学反应 0.33H,以5 Mg的收率获得产物东莨菪苷
参考文献:Hepatoprotective Constituents From The Roots And Stems Of Erycibe Hainanesis
标题:Hepatoprotective Constituents From The Roots And Stems Of Erycibe Hainanesis
摘要:Eleven New Diglycosides,Erycibosides A-K (1-11),Foul New Chlorogenic Acid Derivatives (14-17),And A New Bis-Coumarin (18),Together With 21 Known Compounds,Have Been Isolated From An Etoh Extract Of The Roots And Stems Of Erycibe Hainanesis. Their Structures Were Elucidated By Means Of Spectroscopic Methods And Chemical Evidence. Inhibitory Activities Of Some Of File Compounds D-Galactosamine-Induced Cytotoxicity In Wb-F344 Rat Hepatic Epithelial Stem-Like Cells Were Screened,And Compounds 2,6,10,18,And 32 Showed Potent Hepatoprotective Activities In Concentrations Of 1 X 10(-5) To 1 X 10(-4) M.
DOI:10.1021/np900593Q
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-2023156270-A1
优先权日:2022-02-18
标题:Coumarin synthesis and uses thereof
发明人：CONRATH UWE; LANGENBACH CASPAR; BEYER SEBASTIAN FELIX; SCHWINGES PATRICK; SCHULTHEISS HOLGER; BEESLEY ALEXANDER; LINKE CEDRIC
权利人:BASF SE; RWTH AACHEN
摘要:The present invention relates to genes, materials and methods for coumarin synthesis and the application thereof for improving plant health, preferably against infection by phythopathogenic microorganisms, and/or for improving plant health against coumarin-induced adverse effects on plant health. Furthermore, the invention pertains to methods and uses of such genes and mate- rials for creating correspondingly beneficial plant cells, plant parts and whole plants, and relates to products obtained from such plants or plant parts.
专利号:CZ-2012226-A3
优先权日:2012-03-30
标 题:Process for preparing di- (2-thienyl) glycolic acid scopine ester intermediate in the synthesis of tiotropium bromide
专利号:CZ-2012190-A3
优先权日:2012-03-16
标 题:Process for preparing di- (2-thienyl) glycolic acid scopine ester intermediate in the synthesis of tiotropium bromide and its novel form
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Siwinska J, Kadzinski L, Banasiuk R, Gwizdek-Wisniewska A, Olry A, Banecki B, Lojkowska E, Ihnatowicz A. Identification of QTLs affecting scopolin and scopoletin biosynthesis in Arabidopsis thaliana. BMC Plant Biol. 2014 Oct 18;14:280. doi: 10.1186/s12870-014-0280-9.
2: Xu XK, Chen ZY, Liao LP, Zhang ZJ, Wang ZT. [Determination of scopolin, chlorogenic acid, scopoletin, isochlorogenic acid A, isochlorogenic acid B and isochlorogenic acid C in plants of Erycibe]. Zhongguo Zhong Yao Za Zhi. 2015 Mar;40(6):1119-22. Chinese. Chinese. doi: 10.1021/np300824h. Epub 2013 Mar 19. doi: 10.1016/j.intimp.2009.02.019. Epub 2009 Mar 25. doi: 10.1093/pcp/pcp174. Epub 2009 Dec 3. Erratum in: Plant Cell Physiol. 2010 Feb;51(2):339. Zhou, Zhanghe [corrected to Zhou, Changhe]. doi: 10.1002/bmc.1036. doi: 10.1016/j.phytochem.2008.09.023. Epub 2008 Nov 10.
15: Yoo A, Narayan VP, Hong EY, Whang WK, Park T. Scopolin ameliorates high-fat diet induced hepatic steatosis in mice: potential involvement of SIRT1-mediated signaling cascades in the liver. Sci Rep. 2017 May 22;7(1):2251. doi: 10.1038/s41598-017-02416-6.
合成参考文献
参考文献:10.1093/aob/mch107
摘要:Gómez-Vásquez R, Day R, Buschmann H, Randles S, Beeching JR, Cooper RM. Phenylpropanoids, phenylalanine ammonia lyase and peroxidases in elicitor-challenged cassava (Manihot esculenta) suspension cells and leaves. Ann Bot. 2004 Jul;94(1):87–97.
参考文献:10.1023/b:plan.0000028775.58537.fe
摘要:Gachon C, Baltz R, Saindrenan P. Over-expression of a scopoletin glucosyltransferase in Nicotiana tabacum leads to precocious lesion formation during the hypersensitive response to tobacco mosaic virus but does not affect virus resistance. Plant Mol Biol. 2004 Jan;54(1):137–46. doi: 10.1023/b:plan.0000028775.58537.fe.
参考文献:10.1002/jsfa.4465
摘要:Gnonlonfin BG, Gbaguidi F, Gbenou JD, Sanni A, Brimer L. Changes in scopoletin concentration in cassava chips from four varieties during storage. J Sci Food Agric. 2011 Oct;91(13):2344–7. doi: 10.1002/jsfa.4465.
参考文献:10.1016/j.phytochem.2003.10.015
摘要:Gális I, Kakiuchi Y, Simek P, Wabiko H. Agrobacterium tumefaciens AK-6b gene modulates phenolic compound metabolism in tobacco. Phytochemistry. 2004 Jan;65(2):169–79. doi: 10.1016/j.phytochem.2003.10.015.
参考文献:10.1080/1028602042000204090
摘要:Shi H-, Long B-, Cui X-, Min Z-. A new bisabolane sesquiterpenoid fromEuphorbia chrysocoma. Journal of Asian Natural Products Research. 2005 Dec;7(6):857–60. doi: 10.1080/1028602042000204090.
📝 需求与反馈
尽可能描述清楚需求与问题信息
