CAS: 458-37-7; (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione

上下游产品

CAS号121-33-5 香草醛 | CAS号123-54-6 乙酰丙酮 | CAS号123-08-0 4-羟基苯甲醛; 对羟基苯甲醛 | CAS号100-52-7 苯甲醛 | CAS号112494-43-6 (1ξ)-1-hydroxy-... | CAS号36062-04-1 四氢姜黄素 | CAS号36062-05-2 六氢姜黄素 | CAS号36062-07-4 八氢姜黄素 | CAS号19697-86-0 curcumin 4,4'-d... | CAS号121-33-5 香草醛 | CAS号150-60-7 二苄基二硫 | CAS号1118765-51-7 (E)-7-(benzylth... | CAS号3535-30-6 4-乙氧基-3-甲氧基苯甲酸

香草醛置于boron Trioxide体系中,用 乙酸乙酯 作为反应溶剂,化学反应 3.0H,反应生成 姜黄素
参考文献:不对称姜黄素的改进合成及其作为抗氧化剂的评估
标题:不对称姜黄素的改进合成及其作为抗氧化剂的评估
摘要:本文报道了使用 Pabon 法合成 12 种不对称姜黄素类似物.一般来说,先前报道的不对称姜黄素的产量,如9A (53%),9C (38%) 和9K (38%),一直处于中等或低水平.在此,我们提出低产率是由于反应介质中存在水和n-Bunh 2所致.为了证明这个公式化的假设,我们已经证明可以通过向反应混合物中添加分子筛 (Ms) (4 å) 来提高产率,从而减少水的干扰.因此,除9B (36.7%),9G (34%) 和9L外,获得了更高的产量 (41-76%)(39.5%).此外,本文首次报道了化合物9B,9D,9E,9F,9G,9H,9I,9J和9L .这些合成化合物的结构通过光谱和质谱分析确定.评估了这些合成的不对称姜黄素的自由基清除能力,并将其与阳性对照丁基化羟基甲苯 (Bht) 的自由基清除能力进行了比较.在合成的不对称姜黄素中,化合物9A (Ic 50 = 37.57 +/-0
DOI:10.3390/molecules27082547

专利信息

专利号:WO-2024220674-A1
优先权日:2023-04-18
标题:Timescale-guided microfluidic synthesis of polyphenol-iron iii network nanocapsules of hydrophobic drugs
发明人：YEO YOON; HAN BUMSOO; SHEN YINGNAN
权利人:PURDUE RESEARCH FOUNDATION
摘要:A scalable method of continuous microfluidic synthesis of tannic acid-iron III (TA-FeIII) network (TFN) nanocapsules of a hydrophobic drug; a scalable method of continuous microfluidic synthesis of epigallocatechin-3-gallate iron III (EGCG-FeIII) network, (EFN) nanocapsules; hydrophobic drug nanocapsules synthesized in accordance with the method; and a method of administering a hydrophobic drug to a patient in need thereof by administering to the patient the hydrophobic drug nanocapsules.

专利号:US-2023286893-A1
优先权日:2022-03-09
标题 :Vanillylidenechloroacetone and its use thereof in synthesis of calebin-a
发明人：MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; MUTHUKAMAN NAGARAJAN; PENTAKOTA PARADESI NAIDU
权利人:MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; MUTHUKAMAN NAGARAJAN; PENTAKOTA PARADESI NAIDU
摘要:The present invention discloses a compound, Vanillylidenechloroacetone (VCA)—1-Chloro-4-(4′-hydroxy-3′-methoxy-phenyl)-but-3-en-2-one, and the process of preparing the same. The invention also discloses a process for synthesis of Calebin-A from Vanillylidenechloroacetone.

专利号:US-2023091651-A1
优先权日:2021-09-20
标 题:Dietary supplement and method for synthesis of same
发明人：WYNN JASON R
权利人:StrongCell LLC
摘要:A dietary supplement and method for synthesis of the same are disclosed. In one embodiment of the method, an NADH component is provided that includes at least partially microencapsulated nicotinamide having nicotinamide blended with water. A supplement component, such as collagen, coenzyme Q10, vitamins, and minerals, is provided. A mixed component, which is a liquid, is formed by mixing the NADH component with the supplement component at ambient conditions. The mixed component is subjected to a fill production process.

专利号:US-5679864-A
优先权日:1995-11-03
标题:Process for the synthesis of curcumin-related compounds
发明人：KRACKOV MARK HARRY; BELLIS HAROLD EDWARD
权利人:GENE PRINT INC
摘要:The invention is directed to a process for the synthesis of curcumin and curcumin-related compounds by reacting the enol form of a 2,4-diketone with a monocarbocyclic aldehyde in the presence of an organic amine catalyst. The reactants are dissolved in a highly polar, aprotic organic solvent. The curcumin-related product is recovered in crystalline form by precipitation from the reaction mass and solvent recrystallization.

专利号:US-7507864-B2
优先权日:2006-08-01
标题:Method for the synthesis of curcumin analogues
发明人：MILLER JEFFREY CHRISTOPHER; MITCHELL MIGUEL O
权利人:SALISBURY UNIVERSITY
摘要:The present invention relates to improved methods for achieving the synthesis of 1,7-diaryl-1,6-heptadiene-3,5-diones, and in particular curcumin and its analogues. The invention provides a process for synthesizing such compounds in substantial yield and purity using environmentally benign processes and materials. The invention also relates to the use of such synthesized products in the treatment of Alzheimer's Disease and other diseases.

专利号:US-2012003164-A1
优先权日:1998-12-30
标题 :Cosmetic or dermatological composition containing an active agent which stimulates synthesis of the protein hsp 32 in the skin
发明人：NIZARD CARINE; MOREAU MARIELLE; BONTE FREDERIC
权利人:NIZARD CARINE; MOREAU MARIELLE; BONTE FREDERIC; DIOR CHRISTIAN PARFUMS
摘要:A dermatological or cosmetological composition for an external topical administration, included together with pharmaceutically and/or cosmetologically acceptable excipients: at least one UVA-stabilizing and/or UVB-stabilizing screening agent, at least one compound capable of activating the endogenous synthesis of Heat Shock Protein (HSP) 32 or a functional peptide fragment of such a protein, and forskolin or any extract containing it.