CAS: 37680-65-2; 2,2',5-Trichlorobiphenyl

该化合物是一种属于多氯联苯类的氯化联苯化合物,其特征是联苯结构中存在三氯原子,具体在2,2'和5'位置上.该化合物在室内温度下一般没有颜色,在黄色的黄色固体中无色,在水中无法溶解,但在有机溶剂中却无法溶解.2,2,2欧元,5欧元-二氯联苯具有热稳定性,耐降解性,这助长了该物质在环境中的持久性.该物质一直被用于各种工业用途,包括作为电气设备中的电动液体和热传输媒介.然而,由于其毒性特征和潜在的环境影响,包括生物蓄积和内分泌干扰,许多国家对其生产和使用进行了严格的管制或禁止.在处理该化合物时,安全措施对于减少接触风险至关重要.

结构式图片

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35693-99-3 25569-80-6 41464-41-9

欧盟法规

ECHA物质C&L通报

上下游产品

2,2',5,5'-Tetrachlorobiphenyl 2,2',3,5'-Tetrachlorobiphenyl

合成工艺路线路线简述

    📜2,5-二氯苯胺,氯苯置于sodium Acetate,亚硝酸体系中,化学反应生成2,2,5-三氯联苯醚
    参考文献:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
    标题:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
    摘要:Physical,Spectral And Chromatographic Data For All 209 Individual Pcb Congeners Is Presented. The Individual Congeners Were Synthesized And Then Isolated And Purified. Recent Emphasis On The Source Of The Toxicity Of Commercial Pcb Formulations Has Increased The Need For A Complete Set Of The Pcb Congeners. Through The Use Of Two Capillary Gc Columns: 40% octadecyl/ 15% Phenyl Methyl Siloxane And 50% Phenyl Methyl Siloxane,It Was Possible To Separate 201 Pcb Congeners With Only Four Unresolved Pairs. The Data Compiled In This Study For All 209 Congeners Will Aid In The Identification Of Selected Individual Components Of These Environmental Pollutants. The Use Of This Data Also Presents The Opportunity For The Improved Quantification Of The Commercial Pcb Formulations.
    Doi:10.1016/0045-6535(95)00140-4

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Hikaru Suenaga, Et Al. Alteration Of Regiospecificity In Biphenyl Dioxygenase By Active-Site Engineering. J Bacteriol. 2002 Jul;184(13):3682-8.
    [参考文献]: J D Haddock, Et Al. Dihydroxylation And Dechlorination Of Chlorinated Biphenyls By Purified Biphenyl 2,3-Dioxygenase From Pseudomonas Sp. Strain Lb400. J Bacteriol. 1995 Jan;177(1):20-6.
    [参考文献]: M H Li, Et Al. Uterotropic And Enzyme Induction Effects Of 2,2',5-Trichlorobiphenyl. Bull Environ Contam Toxicol. 1995 Apr;54(4):494-500.
    [参考文献]: S A Saghir, Et Al. Distribution And Metabolism Of 2,5,2'-Trichlorobiphenyl In Houseflies (Musca Domestica L.). Bull Environ Contam Toxicol. 1992 Dec;49(6):839-46.
    [参考文献]: S A Saghir, Et Al. Influence Of Enzyme Levels On The Toxicity And In Vitro Metabolism Of 2,2',5-Trichlorobiphenyl In Houseflies. Ecotoxicol Environ Saf. 1994 Jul;28(2):111-20.

    合成参考文献


    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
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