CAS: 3768-55-6; N-Trimethylsilylaniline

该化合物是一种有机硅化合物,其特点是三甲基组和联苯环附属的矿物质组存在硅原子结扎,该化合物通常具有与硅和氨有关的特性,包括由于有矿功能组的存在而具有的潜在反应性,这些功能组可以参与各种化学反应,例如核生殖替代;硅原子有助于化合物的稳定性,并可能增强其疏水特性;此外,苯基组的存在可以影响化合物的溶性以及与其他有机材料的相互作用;各种应用中,包括用作合金剂,硅酮配方,或合成更为复杂的有机硅化合物;在处理和储存时,应当参考安全数据,如同所有化学物质一样,以确保根据潜在毒性或再活性采取适当的预防措施.

结构式图片

上下游产品

chloro-trimethyl-silane aniline 1,1,1,3,3,3-hexamethyl-disilazane 1,1,1-Trimethyl-3,3,3-triaethyl-disilazanTrimethylmethoxysilane diethyl phenylphosphoramidite 1,1,1-trimethyl-N-phenyl-N-(trimethylsilyl)-silanamine Di-n-propyl-phenyl(trimethylsilyl)phosphoramidit

合成工艺路线路线简述

  • 合成目标产物 N-Trimethylsilylaniline 主要起始原料 Chlorotrimethylsilane And Aniline
  • (文献来源)合成步骤主要原料 Chlorotrimethylsilane 和 Aniline
📜三甲基硅烷基二乙胺置于c6H5Nh2体系中,化学反应生成1,1,1-三甲基-N-苯基哌啶
参考文献:Methylanilinosilanes And Ethylanilinosilanes; Reactions Of Anilinosilanes
标题:Methylanilinosilanes And Ethylanilinosilanes; Reactions Of Anilinosilanes
摘要:
Doi:10.1021/ja01156A097

专利信息


专利号:US-4914233-A
优先权日:1988-03-01
标题:Synthesis of beta-thymidine
发明人:FRESKOS JOHN N; SENARATNE K PUSHPANANDA A
权利人:ETHYL CORP
摘要:A process is provided in which a mixture of alpha- and beta-anomers is converted selectively to the desired beta-thymidine. The process involves the following steps: (a) converting a mixture of alpha- and beta-anomers of tetra-O-acylribofuranose to tri-O-acyl-β-ribothymidine; (b) converting tri-O-acyl-β-ribothymidine to β-ribothymidine; (c) converting β-ribothymidine to 2,2'-anhydro-β-thymidine; (d) converting 2,2'-anhydro-β-thymidine to 2'-halo-2'-deoxy-5-methyluridine; and (e) converting 2'-halo-2'-deoxy-5-methyluridine to beta-thymidine. The mixture of alpha- and beta-anomers of tetra-O-acylribofuranose may be produced by any suitable procedure such as by converting lower alkyl ribofuranoside to the tetra-O-acylribofuranose mixture. The lower alkyl ribofuranosides may in turn be produced by various methods. However, a desirable way of effecting this conversion involves use of D-ribose as the starting material which is converted to the lower alkyl ribofuranoside.

专利号:US-6093825-A
优先权日:1998-05-27
标 题:Methods for preparation of 1,2-dihydroquinolines
发明人:BENDER REINHOLD H W; EDWARDS JAMES P; JONES TODD K
权利人:AMERICAN HOME PROD; LIGAND PHARM INC
摘要:Methods for conversion of anilines to 1,2-dihydroquinolines. 1,2-dihydroquinoliiies are generated from combining an aniline, a silylating agent, and further condensing with a ketone in the presence of a catalyst. In one aspect, the silylation of the aniline may be performed in a one-step synthesis by adding the silylating, agent to the same reaction vessel as the ketone, aniline, and catalyst. In a second aspect, the 1,2-dihydroquinoline is generated in a two-step synthesis where an N-silyl aniline is formed prior to the addition of the ketone and catalyst.

专利号:US-2023140949-A1
优先权日:2020-05-13
标 题 :Method for the synthesis of isocyanates

专利号:EP-4149920-B1
优先权日:2020-05-13
标 题 :Process for the synthesis of isocyanates
发明人:KROKE EDWIN; GRÜNDLER FRANZISKA; HERBIG MARCUS; BAUMHARDT MARLENE-KIRSTIN
权利人:UNIV FREIBERG TECH BERGAKADEMIE

专利号:ES-2994304-T3
优先权日:2020-05-13
标 题 :Process for the synthesis of isocyanates

专利号:EP-4149920-A1
优先权日:2020-05-13
标 题 :Process for the synthesis of isocyanates

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Braverman, S.; Cherkinsky, M.; Birsa, M. L., Science of Synthesis, (2005) 18, 99.
摘要:Masse, C. E., Science of Synthesis, (2007) 20, 342.
摘要:Alajarín, M.; López-Leonardo, C.; Berná, J., Science of Synthesis, (2007) 31, 1877.
摘要:Scholz, U.; Schlummer, B., Science of Synthesis, (2007) 31, 1658.
摘要:Chiara, J. L., Science of Synthesis, (2007) 31, 1701.
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