合成目标产物 N-Trimethylsilylaniline 主要起始原料 Chlorotrimethylsilane And Aniline
(文献来源)合成步骤主要原料 Chlorotrimethylsilane 和 Aniline
📜三甲基硅烷基二乙胺置于c6H5Nh2体系中,化学反应生成1,1,1-三甲基-N-苯基哌啶 参考文献:Methylanilinosilanes And Ethylanilinosilanes; Reactions Of Anilinosilanes 标题:Methylanilinosilanes And Ethylanilinosilanes; Reactions Of Anilinosilanes 摘要: Doi:10.1021/ja01156A097
专利信息
专利号:US-4914233-A 优先权日:1988-03-01 标题:Synthesis of beta-thymidine 发明人:FRESKOS JOHN N; SENARATNE K PUSHPANANDA A 权利人:ETHYL CORP 摘要:A process is provided in which a mixture of alpha- and beta-anomers is converted selectively to the desired beta-thymidine. The process involves the following steps: (a) converting a mixture of alpha- and beta-anomers of tetra-O-acylribofuranose to tri-O-acyl-β-ribothymidine; (b) converting tri-O-acyl-β-ribothymidine to β-ribothymidine; (c) converting β-ribothymidine to 2,2'-anhydro-β-thymidine; (d) converting 2,2'-anhydro-β-thymidine to 2'-halo-2'-deoxy-5-methyluridine; and (e) converting 2'-halo-2'-deoxy-5-methyluridine to beta-thymidine. The mixture of alpha- and beta-anomers of tetra-O-acylribofuranose may be produced by any suitable procedure such as by converting lower alkyl ribofuranoside to the tetra-O-acylribofuranose mixture. The lower alkyl ribofuranosides may in turn be produced by various methods. However, a desirable way of effecting this conversion involves use of D-ribose as the starting material which is converted to the lower alkyl ribofuranoside.
专利号:US-6093825-A 优先权日:1998-05-27 标 题:Methods for preparation of 1,2-dihydroquinolines 发明人:BENDER REINHOLD H W; EDWARDS JAMES P; JONES TODD K 权利人:AMERICAN HOME PROD; LIGAND PHARM INC 摘要:Methods for conversion of anilines to 1,2-dihydroquinolines. 1,2-dihydroquinoliiies are generated from combining an aniline, a silylating agent, and further condensing with a ketone in the presence of a catalyst. In one aspect, the silylation of the aniline may be performed in a one-step synthesis by adding the silylating, agent to the same reaction vessel as the ketone, aniline, and catalyst. In a second aspect, the 1,2-dihydroquinoline is generated in a two-step synthesis where an N-silyl aniline is formed prior to the addition of the ketone and catalyst.
专利号:US-2023140949-A1 优先权日:2020-05-13 标 题 :Method for the synthesis of isocyanates
专利号:EP-4149920-B1 优先权日:2020-05-13 标 题 :Process for the synthesis of isocyanates 发明人:KROKE EDWIN; GRÜNDLER FRANZISKA; HERBIG MARCUS; BAUMHARDT MARLENE-KIRSTIN 权利人:UNIV FREIBERG TECH BERGAKADEMIE
专利号:ES-2994304-T3 优先权日:2020-05-13 标 题 :Process for the synthesis of isocyanates
专利号:EP-4149920-A1 优先权日:2020-05-13 标 题 :Process for the synthesis of isocyanates
摘要:Braverman, S.; Cherkinsky, M.; Birsa, M. L., Science of Synthesis, (2005) 18, 99. 摘要:Masse, C. E., Science of Synthesis, (2007) 20, 342. 摘要:Alajarín, M.; López-Leonardo, C.; Berná, J., Science of Synthesis, (2007) 31, 1877. 摘要:Scholz, U.; Schlummer, B., Science of Synthesis, (2007) 31, 1658. 摘要:Chiara, J. L., Science of Synthesis, (2007) 31, 1701.