CAS: 26247-79-0; Sodium Polyglutamate

上下游产品

L-Pyroglutamic acid α-ketoglutaric acid disodium salt(S)-1-Pyrrolidin-2-yl-methanol (S)-Pyroglutaminol sodium L-pyroglutamate N-2-ethylhexanoyl-L-glutamic acid N,N'-(dibutylamide)

专利信息

专利号:US-2003049619-A1
优先权日:2001-03-21
标题 :Methods for the synthesis of polynucleotides and combinatorial libraries of polynucleotides
发明人：DELAGRAVE SIMON; MARRS BARRY
摘要:Methods for the synthesis of polynucleotides and derivatives thereof are provided. Methods for the preparation of combinatorial libraries of polynucleotides are also provided. In addition, methods for the preparation and identification of polynucleotides having a predetermined property are provided.

专利号:US-6699981-B2
优先权日:1999-09-22
标题 :Method and compositions for improved polynucleotide synthesis
发明人：YANG SHUWEI
权利人:GENECOPOEIA INC
摘要:The sensitivity and specificity of polynucleotide synthesis is increased by protecting the 3'-end of an oligonucleotide used as a primer in the synthesis of the polynucleotide. Protection of the 3'-end of an oligonucleotide prevents non-specific chain elongation. Removal of blocking group an elevated temperature, using a thermostable enzyme, permits template-specific polynucleotide synthesis. The present invention also provides oligonucleotides with a 3' end protected by a blocking group and a thermostable enzyme capable of removing the blocking group at an elevated temperature. The compositions and methods of the invention are very useful in a variety of techniques for DNA/RNA amplification and analysis, including medical genetics research and diagnosis, pathogen detection, forensic, and animal and plant genetics applications, among others.

专利号:US-10760063-B2
优先权日:2014-10-20
标 题:Modified template-independent enzymes for polydeoxynucleotide synthesis
发明人：EFCAVITCH J WILLIAM; TUBBS JULIE L; SINHA PREM; STEC BOGUSLAW
权利人:MOLECULAR ASSEMBLIES INC
摘要:The invention includes methods for identifying polymerases, such as modified terminal nucleotidyl transferases (TdT), that are capable of binding nucleotides comprising removable 3′-O-blocking moieties to a nucleic acid initiator, without the use of a template. The invention further includes the identified polymerases, and methods of using the polymerases for de novo synthesis of predetermined oligonucleotide sequences.

专利号:US-11390858-B2
优先权日:2014-10-20
标 题:Modified template-independent enzymes for polydeoxynucleotide synthesis
发明人：TUBBS JULIE L; SINHA PREM; STEC BOGUSLAW; WILSON CHRISTOPHER; EFCAVITCH J WILLIAM; SAMMOND DEANNE W
权利人:MOLECULAR ASSEMBLIES INC
摘要:The invention includes methods for identifying polymerases, such as modified terminal nucleotidyl transferases (TdT), that are capable of binding nucleotides comprising removable 3′-O-blocking moieties to a nucleic acid initiator, without the use of a template. The invention further includes the identified polymerases, and methods of using the polymerases for de novo synthesis of predetermined oligonucleotide sequences.

专利号:US-10774316-B2
优先权日:2014-10-20
标题 :Modified template-independent enzymes for polydeoxynucleotide synthesis
发明人：EFCAVITCH J WILLIAM; TUBBS JULIE L; SINHA PREM; STEC BOGUSLAW
权利人:MOLECULAR ASSEMBLIES INC
摘要:The invention includes methods for identifying polymerases, such as modified terminal nucleotidyl transferases (TdT), that are capable of binding nucleotides comprising removable 3′-O-blocking moieties to a nucleic acid initiator, without the use of a template. The invention further includes the identified polymerases, and methods of using the polymerases for de novo synthesis of predetermined oligonucleotide sequences.

专利号:US-2004053274-A1
优先权日:2002-09-04
标 题 :Gene cluster of vicenistatin biosynthesis, a vicenisamine glycosyltransferase polypeptide, and a gene encoding the polypeptide
发明人：KAKINUMA KATSUMI
权利人:TOKYO INST TECH
摘要:To achieve enzymatic production of vicenistatin, a valuable compound, this invention provides enzymes involved in biosynthesis of vicenistatin and genes encoding the enzymes. This invention provides base sequence of the vin cluster which encodes enzyme complex responsible for biosynthesis of vicenistatin. This invention further provides a glycosyltransferase (VinC enzyme), which catalyzes production of vicenistatin using dTDP-vicenisamine as a substrate. Moreover, this invention provides a gene (vinC gene) encoding the enzyme. The VinC enzyme is useful for enzymatic synthesis of valuable compound vicenistatin. Furthermore, it is suggested that use of the VinC enzyme will enable development of novel polyketide glycosides.