CAS: 1458-98-6; 3-Bromo-2-Methylpropene

该化合物其结构特征为甲基苯丙胺的溴化衍生物; 色化黄色液体,其色素味不亮,表明其活性及在有机合成中的潜在用途; 化合物在碳链中具有双重联结性,有助于其不饱和,并使其成为各种化学反应的有用中间体,包括核生殖替代和聚合物; 甲基溴在有机溶剂中可溶解,但水溶性有限,反映其疏水性; 需要谨慎处理这一物质,因为它可能很危险; 它可能会对皮肤,眼睛和呼吸系统造成刺激; 此外,它被归类为潜在的环境污染物,需要适当的处置方法. 由于它的再活性,甲基溴被用于各种化学化合物的合成,包括药物和农用化学,突出其在有机化学领域的重要性.

结构式图片

相似化合物

20038-12-4 17200-53-2 870-63-3

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号563-47-3 3-氯-2-甲基-1-丙烯(MAC) | CAS号504-61-0 巴豆醇 | CAS号115-11-7 2-甲基丙烯 | CAS号594-34-3 1,2-二溴-2-甲基丙烷 | CAS号631-28-7 Propane,1,2,3-t... | CAS号67-56-1 甲醇 | CAS号107791-76-4 2-methylhepta-1... | CAS号110124-13-5 3-methoxy-2-(2-... | CAS号109930-20-3 2-methyl-3-prop... | CAS号4911-54-0 4-甲基-4-戊烯酸乙酯 | CAS号90433-27-5 3-(3-甲基-3-丁烯-1-基)溴苯 | CAS号19549-80-5 4,6-二甲基-2-庚酮 | CAS号2305-59-1 4,4-二甲基-2-咪唑并啉 | CAS号1896-62-4 反式苯亚甲基丙酮 | CAS号24309-27-1 Thi°Cyanic acid...

合成工艺路线路线简述

    3-氯-2-甲基丙烯置于sodium Bromide体系中,用85%的收率获得3-溴-2-甲基丙烯
    参考文献:Process For Producing Allyl Bromides
    标题:Process For Producing Allyl Bromides
    摘要:通过卤素交换反应,使用金属溴化物与烯丙基氯反应,在无质子极性溶剂中进行反应,从而生产烯丙基溴的改进工艺.本发明所得到的烯丙基溴可用作生产药品,农业化学品,染料等中间体.

    海关参考信息

    专利信息


    专利号:US-9126995-B2
    优先权日:2011-11-08
    标题:Method for catalytic asymmetric synthesis of optically active isoxazoline compound and optically active isoxazoline compound
    发明人:TOYAMA KEN-ICHI; MORIYAMA YUJI; MATOBA KAZUTAKA; YAOSAKA MANABU; IKEDA EITATSU
    权利人:NISSAN CHEMICAL IND LTD
    摘要:There is provided a method for catalytic asymmetric synthesis of optically active isoxazoline compound and an optically active isoxazoline compound. A method for catalytic asymmetric synthesis of optically active isoxazoline compound of a formula (6) including reacting an α,β-unsaturated carbonyl compound of a formula (1) and a hydroxylamine in a solvent in the presence of a base by adding a chiral phase transfer catalyst. An optically active isoxazoline compound of a formula (13) that can be synthesized by the method.

    专利号:US-9879043-B1
    优先权日:2013-06-06
    标 题:Synthesis of non-natural cofactor analogs of S-adenosyl-L-methionine using methionine adenosyltransferase
    发明人:THORSON JON; HUBER TYLER; ZHANG JIANJUN; Singh Shanteri
    权利人:UNIV KENTUCKY RES FOUND
    摘要:The present disclosure relates to the synthesis of non-natural analogs of S-adenosyl-L-methionine (SAM) and/or of Se-adenosyl-L-methionine (SeAM) by reacting a methionine analog and adenosine triphosphate (ATP) in the presence of at least one methionine adenosyltransferase (MAT), and to use thereof with downstream SAM and/or SeAM utilizing enzymes. The non-natural analogs of SAM and/or SeAM have the general formula: n nwhere X is S or Se, and R 1 is an alkyl group.

    专利号:US-9249165-B2
    优先权日:2013-08-30
    标题 :Slurry phase direct synthesis of organohalosilanes from cyclone fines
    发明人:LEWIS KENRICK MARTIN; ZHU YANJUN; MEREIGH ABELLARD T; RAZZANO JOHN; NEELY JOHN DAVID
    权利人:MOMENTIVE PERFORMANCE MAT INC
    摘要:The present invention is directed to a process for the synthesis of organohalosilane monomers, comprising the steps of (1) forming a slurry of cyclone fines, ultra fines and/or spent contact mass in a thermally stable solvent and reacting the agitated slurry with an organohalide of the formula R 1 X in the presence of an additive for a time and at a temperature sufficient to produce organohalosilane monomers having the formulae R 1 SiHX 2 , R 1 2 SiHX, R 1 3 SiX, R 1 SiX 3 , and R 1 2 SiX 2 ; wherein R 1 is a saturated or unsaturated aromatic group, a saturated or unsaturated aliphatic group, alkaryl group, or cycloaliphatic hydrocarbyl group, and X is a halogen; and (2) recovering said organohalosilane monomers.

    专利号:US-2006079719-A1
    优先权日:2002-04-16
    标 题 :Aminated compounds bearing at least an allyl and a difluoromethyl and method used for synthesis thereof
    发明人:BONNET-DELPON DANIELE; BEGUE JEAN-PIERRE; LEGROS JULIEN; CROUSSE BENOIT; MEYER FRANCK
    权利人:BONNET-DELPON DANIELE; BEGUE JEAN-PIERRE; LEGROS JULIEN; CROUSSE BENOIT; MEYER FRANCK
    摘要:The invention relates to aminated compounds bearing at least an allyl and a difluoromethyl and a method used for synthesis thereof. Said compounds comprise at least one carbon bearing: an amine function, an allyl or propargyl radical, a difluoromethylene group, and a hydrogen or a hydrocarbon radical, advantageously selected among those which are electron donors or hardly electroattractive (; 0. 1). The invention is useful for synthesis of fluorinated compounds.

    专利号:US-6313068-B1
    优先权日:1998-08-20
    标 题:Synthesis methods, complexes and delivery methods for the safe and convenient storage, transport and application of compounds for inhibiting the ethylene response in plants
    发明人:DALY JAMES; KOURELIS BOB
    权利人:AGROFRESH INC
    摘要:The present invention generally relates to the regulation of plant physiology, in particular to methods for inhibiting the ethylene response in plants or plant products, and has three embodiments. The first embodiment relates to methods of minimizing impurities capable of reversibly binding to plant ethylene receptor sites during the synthesis of cyclopropene and its derivatives such as methylcyclopropene, thereby avoiding the negative effects these impurities have on plants treated with cyclopropene and its derivatives. The second embodiment relates to complexes formed from molecular encapsulation agents such as cyclodextrin, and cyclopropene and its derivatives such as methylcyclopropene, in addition to cyclopentadiene and diazocyclopentadiene and their derivatives, thereby providing a convenient means for storing and transporting these compounds capable of inhibiting the ethylene response in plants, which are reactive gases and highly unstable because of oxidation and other potential reactions. The third embodiment relates to convenient methods of delivering to plants these compounds capable of inhibiting the ethylene response in the plants in order to extend their shelf life.

    专利号:US-8309599-B2
    优先权日:2006-09-08
    标题 :Synthesis of FR901464 and analogs with antitumor activity
    发明人:KOIDE KAZUNORI; ALBERT BRIAN J; SIVARAMAKRISHNAN ANANTHAPADMANABHAN
    权利人:KOIDE KAZUNORI; ALBERT BRIAN J; SIVARAMAKRISHNAN ANANTHAPADMANABHAN; UNIV PITTSBURGH
    摘要:The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing.
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    合成参考文献


    摘要:Sartori, G.; Maggi, R., Science of Synthesis, (2010) 47, 520.
    摘要:Snaith, J. S., Science of Synthesis Knowledge Updates, (2011) 2, 199.
    摘要:Spitzner, D., Science of Synthesis Knowledge Updates, (2016) 1, 121.
    摘要:Tymoshenko, D. O., Science of Synthesis Knowledge Updates, (2012) 3, 385.
    摘要:Collings, J. C., Science of Synthesis Knowledge Updates, (2013) 4, 220.
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