CAS: 704-10-9; 1-(2,4-Dichloro-5-Fluorophenyl)Ethanone

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CAS号1435-48-9 2,4-二氯氟苯 | CAS号108-24-7 乙酸酐 | CAS号75-36-5 乙酰氯 | CAS号1481-63-6 2,4-二氯-5-氟溴苯 | CAS号104599-90-8 3-Quinolinecarb... | CAS号259228-30-3 1-(2,4-dichloro... | CAS号98105-79-4 7-氯-6-氟-1-对氟苯基-... | CAS号86522-89-6 2,4-二氯-5-氟苯甲酸 | CAS号86393-33-1 环丙羧酸 | CAS号98106-17-3 双氟沙星 | CAS号86483-51-4 2,4-二氯-5-氟-Β-氧代苯丙酸乙酯 | CAS号98105-99-8 沙拉沙星 | CAS号106809-14-7 2,4-二氯-3-硝基-5-氟苯甲酸 | CAS号114610-10-5 1-(4-fluorophen...

2,4-二氯氟苯 反应生成 2,4-二氯-5-氟苯乙酮
参考文献:5-Hydroxymethyl-Oxazolidin-2-One-Derivatives And Their Uses As Antibacterials
标题:5-Hydroxymethyl-Oxazolidin-2-One-Derivatives And Their Uses As Antibacterials
摘要:本发明涉及一种新的嵌合抗生素,其化学式为i式,其中r1代表oh,Opo3H2或ocor5;r2代表h,Oh或opo3H2;a代表n或cr6;r3代表h或氟;r4是h,(C1-C3)烷基或环烷基;r5是天然氨基酸残基,天然氨基酸对映体或二甲氨基甘氨酸残基;r6代表h,烷氧基或卤素;n为0或1;以及i式化合物的盐(特别是药学上可接受的盐).这些嵌合化合物在制造治疗感染(例如细菌感染)的药物方面是有用的.

专利信息

专利号:WO-2010058421-A3
优先权日:2008-11-18
标题 :A process for synthesis of 2, 4-dichloro-5- fluoroacetophenone (dcfa)
发明人：MANDAL SISIR; PATIL NARENDRA; SULEMAN INAMDUR; MORE VINOD; PURI PRASHANT
权利人:ADITYA BIRLA SCI & TECH CO LTD; MANDAL SISIR; PATIL NARENDRA; SULEMAN INAMDUR; MORE VINOD; PURI PRASHANT
摘要:A process for synthesis of 2,4-dichloro-5-fluoro acetophenone (DCFA) is disclosed. The process comprises first reacting 3,4-dichloronitrobenzene with potassium fluoride having bulk density in the range of 0.2 to 1.3, to form a fluorinated intermediate product, then reacting the intermediate product with chlorine to form dichlorofluorobenzene and finally acylating dichlorofluorobenzene using an acylating agent to form a mixture containing DCFA along with impurities, followed by purification and enrichment of DCFA in the mixture by melt crystallization.

专利号:WO-2010058421-A2
优先权日:2008-11-18
标题:A process for synthesis of 2, 4-dichloro-5- fluoroacetophenone (dcfa)

专利号:CN-116693375-B
优先权日:2023-08-08
标 题 :A kind of synthesis method of 2,4-dichloro-5-fluoroacetophenone

专利号:CN-116836114-A
优先权日:2023-08-31
标题 :Synthesis method of cyclopropanecarboxylic acid

专利号:CN-103304422-A
优先权日:2013-07-15
标 题 :A kind of one-pot synthesis method of 2,4-dichloro-3-nitro-5-fluorobenzoic acid