CAS: 6933-26-2; (5-Ethylthiophen-2-yl)(Phenyl)Methanone

上下游产品

2-ethylthiophene benzoyl chloride 5-Ethyl-2-thiophencarbonsaeurechlorid phenylzinc(II) bromideTetrabromothiophene Pummerer ketone 4-methyl-2-(4-methylphenoxy)phenol 2,2'-Dihydroxy-4,4'-dimethylbiphenyl

📜噻洛芬酸 以 Aq. Phosphate Buffer 作为反应溶剂,化学反应生成 替卡西林杂质a
参考文献:时间分辨光谱学研究中性磷酸盐缓冲水溶液中飞虫芬酸从飞秒到最终产物的光化学
标题:时间分辨光谱学研究中性磷酸盐缓冲水溶液中飞虫芬酸从飞秒到最终产物的光化学
摘要:通过飞秒瞬态吸收(fs-Ta),纳秒瞬态吸收(ns-Ta)和纳秒时间分辨共振拉曼(ns-Tr 3)光谱实验研究了噻洛芬酸(tpa)的光脱羧和整体反应机理在中性磷酸盐缓冲溶液(pbs)中.此外,提出了密度泛函理论(dft)计算以帮助解释实验结果.共振拉曼光谱和dft计算结果表明,去质子化的tiprofenic酸(tpa-)形式是在接近中性的pbs水溶液中被光激发的主要物质.fs-Ta实验数据表明最低的激发单重态s 1进行了有效的系统间交叉过程(isc),以快速转变为最低激发的三重态t 1,然后进行脱羧反应反应生成三重态双自由基物质(tb 3).ns-Ta和ns-Tr 3结果观测到了tb 3的质子化过程,产生了一种中性物质(tbp 3),然后该物质通过isc分解而反应生成了单线态tbp物质,该单峰tbp物质进一步反应反应生成了最终产物(dtpa).比较了tpa的现有结果-与文献中去质子化形式的酮洛芬(kp
DOI:10.1021/jp310315F

专利信息

专利号:US-7687635-B2
优先权日:2002-01-22
标 题:Metal complexes useful in metathesis and other reactions
发明人：VERPOORT FRANCIS WALTER CORNELIUS; DE CLERCQ BOB
权利人:TELENE S A S
摘要:This invention provides metal complexes being useful as catalyst components in metathesis reactions and in reactions involving the transfer of an atom or group to an ethylenically or acetylenically unsaturated compound or another reactive substrate and, with respect to a sub-class thereof, for the polymerisation of α-olefins and optionally conjugated dienes, with high activity at moderate tempera-tures. It also provides methods for obtaining polymers with very narrow molecular weight distribution by means of a living reaction. It also provides methods for making said metal complexes and novel intermediates involved in such methods. It further provides derivatives of said metal complexes which are suitable for covalent bonding to a carrier, the product of such covalent bonding being useful as a supported catalyst for heterogeneous catalytic reactions. It also provides a direct one-step synthesis of pyrrole, furan and thiophene compounds from diallyl compounds.

专利号:US-5602267-A
优先权日:1995-05-26
标 题 :Organometallic catalysts for epoxidizing prochiral olefins and a new class of amid-salicylidene ligands
发明人：ZHAO SHU-HAI
权利人:HOECHST CELANESE
摘要:Asymmetric synthesis using a novel catalyst comprising the formula: and which has utility in areas such as epoxidation of olefins.

专利号:US-2007185343-A1
优先权日:2004-02-26
标 题 :Metal complexes for use in olefin metathesis and atom group transfer reactions
发明人：VERPOORT FRANCIS WALTER C; DROZDZAK RENATA A; LEDOUX NELE; ALLAERT BART F
权利人:UNIV GENT
摘要:Improved catalysts useful in a number of organic synthesis reactions such as olefin metathesis and atom or group transfer reactions are made by bringing into contact a multi-coordinated metal complex comprising a multidentate Schiff base ligand, and one or more other ligands, with an acid under conditions such that said acid is able to at least partly cleave a bond between the metal and the multidentate Schiff base ligand of said metal complex, optionally through intermediate protonation of said Schiff base ligand.

专利号:EP-1577282-B1
优先权日:2004-02-26
标 题:Metal complexes for use in olefin metathesis and atom or group transfer reactions
发明人：VERPOORT FRANCIS WALTER CORNELIUS; DROZDZAK RENATA ANNA; LEDOUX NELE; ALLAERT BART FILIP
权利人:TELENE SAS
摘要:Improved catalysts useful in a number of organic synthesis reactions such as olefin metathesis and atom or group transfer reactions are made by bringing into contact a multi-coordinated metal complex comprising a multidentate Schiff base ligand, and one or more other ligands, with an acid under conditions such that said acid is able to at least partly cleave a bond between the metal and the multidentate Schiff base ligand of said metal complex, optionally through intermediate protonation of said Schiff base ligand.

专利号:WO-9420510-A1
优先权日:1993-03-09
标 题 :Homogeneous bimetallic hydroformylation catalysts and processes utilizing these catalysts for conducting hydroformylation reactions
发明人：STANLEY GEORGE G; PENG WEI-JUN
权利人:UNIV LOUISIANA STATE; STANLEY GEORGE G; PENG WEI JUN
摘要:Novel homogeneous bimetallic hydroformylation catalysts, and processes utilizing these catalysts to convert alkenes, particularly alpha olefins, under mild conditions to a product rich in aldehydes, particularly a product containing a high ratio of linear: branched chain aldehydes. The catalysts can be produced from a binucleating tetratertiaryphosphine ligand capable of strongly coordinating two metal centers and holding them in general proximity to one another. Bimetallic catalyst precursors are produced which, on reaction with carbon monoxide and hydrogen, forms the active bimetallic hydroformylation catalyst system. This invention also relates to asymmetric synthesis in which a prochiral or chiral compound is contacted in the presence of an optically pure metal-ligand complex catalyst, in enantiomeric form, to produce an optically active product.