CAS: 499-44-5; 2-Hydroxy-4-Isopropylcyclohepta-2,4,6-Trien-1-One

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Beta-斧松素置于palladium On Activated Charcoal 氢气体系中,用 乙醇 作为反应溶剂,以98%的收率获得产物桧木醇
参考文献:钯介导的溴代tropolones与有机锡的交叉偶联;应用在简明合成β-杜拉布林,β-Thujaplicin,7-甲氧基-4-异丙基马酚酮和β-Thujaplicinol的过程中
标题:钯介导的溴代tropolones与有机锡的交叉偶联;应用在简明合成β-杜拉布林,β-Thujaplicin,7-甲氧基-4-异丙基马酚酮和β-Thujaplicinol的过程中
摘要:在钯(0)的存在下,溴对苯二酮(1),(2)和(3)与有机锡烷交联以产生烷基,烯基或芳基取代的对苯二酚;该方法已被应用于合成单萜β-杜拉布林(4),β-Thujaplicin(5),7-甲氧基-4-异丙基tropolone (7)和β-Thujaplicinol(8).
DOI:10.1039/c39890000616

专利信息

专利号:US-2024082118-A1
优先权日:2021-05-19
标 题:Topical compositions and methods of preparing the same
发明人：ABRAMOVICH SAGI; AVIDOR GAL; LANDA BENZION
权利人:LANDA LABS 2012 LTD
摘要:There is disclosed a composition comprising a water-insoluble thermoplastic compound capable of stimulating collagen synthesis (CSSC), the CSSC having a molecular weight of more than 0.6 kDa and being dispersed in a polar carrier as nano-elements having an average diameter of 200 nm or less and a viscosity of 107 mPa·s or less. The nano-elements of CSSC can be capable of stimulating the synthesis of skin proteins and/or enabling the delivery of active agents upon their application to a surface to be treated therewith. Methods for preparing the compositions and uses thereof are also provided.

专利号:US-11780883-B2
优先权日:2021-06-30
标题 :Derived peptide of lactoferrin and method thereof for promoting and/or increasing lipid synthesis
发明人：HUANG HSIU-CHIN; LIN HSUAN
权利人:RENORIGIN INNOVATION INST CO LTD
摘要:The present invention provides a derived peptide of a lactoferrin, a composition comprising the same and a use thereof for promoting and/or increasing lipid synthesis. The derived peptide of the lactoferrin comprises the amino acid sequence of SEQ ID NO: 01.

专利号:US-2009232915-A1
优先权日:2008-03-14
标 题 :Mixtures with a collagen synthesis boosting action
发明人：SCHMAUS GERHARD; FRANKE HELGE; LANGE SABINE
权利人:SYMRISE GMBH & CO KG
摘要:The invention relates to synergistically active, ternary mixtures which boost collagen synthesis and to the uses thereof, in particular for slowing down skin ageing and for wound healing of damaged skin. The invention furthermore relates to the use of the ternary mixtures according to the invention for treating the oral cavity and pharynx, and in particular therein for preventing and slowing down periodontitis, for building up periodontal connective tissue and for preventing and treating infections in the oral cavity and for wound healing in the oral cavity.

专利号:US-11944609-B1
优先权日:2023-06-16
标题:Antifungal ionic liquid and Amphotericin B combination
发明人：RATHER SAMI-ULLAH; WANI MOHMMAD YOUNUS; BAMUFLEH HISHAM S; ALHUMADE HESHAM; SAEED USMAN; TAIMOOR AQEEL AHMAD; ALALAYAH WALID M; RATHER IRFAN AHMAD
权利人:KING ABDULAZIZ UNIVERISTY; UNIV KING ABDULAZIZ
摘要:Provided herein are ionic liquids that can be used as antifungal agents alone or in combination with Amphotericin B. Also disclosed are methods of synthesis of the ionic liquids and inhibiting fungal growth and methods of treating fungal infections using the disclosed compounds. The disclosure provides antifungal agents that potentiate the antifungal activity of Amphotericin B, a commonly used antifungal drug that could be used alone or in combination. This combination will help control and combat the infections caused by drug resistant Candida. auris in immunocompromised patients.

专利号:US-2025144039-A1
优先权日:2022-07-13
标题:Compositions comprising surface modified globular nano-particles
发明人：ABRAMOVICH SAGI; AVIDOR GAL; LANDA BENZION
权利人:LANDA LABS 2012 LTD
摘要:There are disclosed compositions comprising core-shell nano-elements composed in their core of a water-insoluble thermoplastic compound having a molecular weight of more than 0.6 kDa and in their shell of at least one fatty amine, or a part thereof, the core-shell nano-elements having a viscosity of 107 mPa·s or less and being dispersed in a polar carrier as nano-elements having an average diameter of 200 nm or less. The water-insoluble thermoplastic compound can be capable of stimulating the synthesis of skin proteins and/or enabling the delivery of active agents upon application of the core-shell nano-elements to a surface to be treated therewith. Methods for preparing the composition and uses thereof are also provided.

专利号:US-4975441-A
优先权日:1988-03-23
标 题:Lactams, their synthesis and use in cosmetic compositions
发明人：GIBSON WALTER T
权利人:UNILEVER PATENT HOLDINGS
摘要:A composition suitable for topical application to mammalian skin or hair for inducing, maintaining or increasing hair growth comprises: (i) a chemical inhibitor of glycosidase activity chosen from lactams having the structure: where A<1> and A<6> are -H, -CH3, - @@0, -CH2OT or @@@0 A<1> and A<6> being the same or different, and at least one of which being the group: @ @@o in a lactam ring; and where Q is -OT min , -NHT min or a lactam linkage to A<1> or A<6>; the Q groups being the same or different, and at least one of which is involved in a lactam linkage; and where T is the same or different and is chosen from -H, -CpH2p+1 or a metal ion, T min is -H or -COCpH2p+1, and p is an integer of from 1 to 22; provided that: where any of the Q groups is -OT min or -NHT min , then that group or groups can be of either stereochemical configuration with respect to the plane of the ring; and (ii) a cosmetically acceptable vehicle for the chemical inhibitor. Certain novel lactams are also claimed.