CAS: 3916-78-7; 6-Chloropyridazine-3(2H)-Thione

相似化合物

1445-58-5 1206523-81-0 184219-92-9

上下游产品

CAS号141-30-0 3,6-二氯哒嗪 | CAS号1445-58-5 3,6-二巯基哒嗪 | CAS号17284-97-8 3-氯-6-肼基哒嗪 | CAS号7145-61-1 3-氯-6-甲基磺酰基吡嗪 | CAS号89391-73-1 6-氯-3-吡嗪磺酰氯 | CAS号62645-42-5 3-chloro-6-ethy... | CAS号51389-01-6 3-chloro-6-prop...

📜3,6-二氯哒嗪置于硫化氢,Sodium Ethanolate体系中,用 四氢呋喃 用作溶剂,化学反应 1.0H,以86%的收率获得3-氯-6-巯基哒嗪
参考文献:金属化的ť丁基亚砜,砜和哒嗪和吡嗪磺胺类药物.二嗪的金属化.Xx
标题:金属化的ť丁基亚砜,砜和哒嗪和吡嗪磺胺类药物.二嗪的金属化.Xx
摘要:在哒嗪系列中,已经测试了使用叔丁基亚磺酰基和叔丁基磺酰基作为金属的邻位导向基团.以高收率获得了各种功能化产品.在3-的情况下,叔丁基亚-6-Methoxypyridazine,所述金属化中是区域选择性的邻位的亚磺酰基.2-叔丁基亚磺酰基和2-叔丁基磺酰基吡嗪的金属化得到低至中等的收率.改进了二嗪磺酰胺的合成,并实现了n-叔丁基磺酰胺基吡嗪的金属化.
Doi:10.1002/jhet.5570350228

专利信息

专利号:CN-111699248-A
优先权日:2018-01-31
标题:Biocatalysts and methods for the synthesis of mixed disulfide conjugates of thienopyridine compounds

专利号:US-12188069-B2
优先权日:2018-01-31
标 题 :Biocatalyst and methods for synthesizing mixed disulfide conjugates of thienopyridine compounds
发明人：ZHANG HAOMING
权利人:UNIV MICHIGAN REGENTS
摘要:The present invention relates to methods for synthesizing mixed disulfide conjugates of thienopyridine compounds with a genetically engineered variant of cytochrome P450 BM3 or CYP102A1 as a catalyst, and belongs to the field of chemical synthesis.

专利号:CN-112759553-B
优先权日:2019-11-01
标 题:Synthesis and application of water-soluble pyridazine derivative

专利号:CN-117603143-A
优先权日:2023-11-30
标题:A kind of synthesis method of azinamide 294 impurity

专利号:CN-112759553-A
优先权日:2019-11-01
标 题 :Synthesis and application of a water-soluble pyridazine derivative