专利号:US-10000598-B2 优先权日:2012-10-15 标题:Methods for preparation of molecularly imprinted polymers for wine extraction 发明人:BELBRUNO JOSEPH J 权利人:DARTMOUTH COLLEGE 摘要:Disclosed herein are compositions of, synthesis methods and methods of use for improved molecularly imprinted polymers useful for extracting target molecule compounds of wine.
专利号:US-2006154323-A1 优先权日:2002-06-10 标 题:Method for obtaining dynamic and structural data pertaining to proteins and protein/ligand complexes 发明人:BROWN JONATHAN M; HOMANS STEVEN W; CHENG MINN-CHANG; CHAYKOVSKY MICHAEL; MURRAY JENNY H 权利人:PROSPECT PHARMA 摘要:This invention provides an NMR method for obtaining both entropic and enthalpic data on proteins and protein/ligand complexes which can be used to obtain accurate structural and dynamic data of proteins and protein complexes having a wide range of molecular weights. An embodiment of the invention provides proteins which contain at least one bond vector whose dynamics are to be measured and which is surrounded by NMR inactive nuclei, and amino acids for synthesis of the proteins via chemical means or biological expression. The NMR methods using specifically labeled proteins for analysis result in maximization of the sensitivity and resolution of the NMR experiments, and minimization of the loss of signal due to diffusion.
[参考文献]: Amir Salemi, Et Al. Automated Trace Determination Of Earthy-Musty Odorous Compounds In Water Samples By On-Line Purge-And-Trap-Gas Chromatography-Mass Spectrometry. J Chromatogr A. 2006 Dec 15;1136(2):170-5. [参考文献]: Andreas Peter, Et Al. Occurrence Of Dissolved And Particle-Bound Taste And Odor Compounds In Swiss Lake Waters. Water Res. 2009 May;43(8):2191-200. [参考文献]: G J Pickering, Et Al. Detection Thresholds For 2-Isopropyl-3-Methoxypyrazine In Concord And Niagara Grape Juice. J Food Sci. 2008 Aug;73(6):S262-6. [参考文献]: G J Pickering, Et Al. Determination Of Ortho- And Retronasal Detection Thresholds For 2-Isopropyl-3-Methoxypyrazine In Wine. J Food Sci. 2007 Sep;72(7):S468-72. [参考文献]: Imelda Ryona, Et Al. Rapid Measurement Of 3-Alkyl-2-Methoxypyrazine Content Of Winegrapes To Predict Levels In Resultant Wines. J Agric Food Chem. 2009 Sep 23;57(18):8250-7.
合成参考文献
参考文献:10.1021/jf049927z 摘要:Sala C, Busto O, Guasch J, Zamora F. Influence of vine training and sunlight exposure on the 3-alkyl-2-methoxypyrazines content in musts and wines from the Vitis vinifera variety cabernet sauvignon. J Agric Food Chem. 2004 Jun 02;52(11):3492–7. doi: 10.1021/jf049927z. 参考文献:10.1016/j.chroma.2008.02.088 摘要:Kotseridis YS, Spink M, Brindle ID, Blake AJ, Sears M, Chen X, Soleas G, Inglis D, Pickering GJ. Quantitative analysis of 3-alkyl-2-methoxypyrazines in juice and wine using stable isotope labelled internal standard assay. J Chromatogr A. 2008 May 09;1190(1-2):294–301. doi: 10.1016/j.chroma.2008.02.088. 参考文献:10.1002/jsfa.6760 摘要:Kögel S, Botezatu A, Hoffmann C, Pickering G. Methoxypyrazine composition of Coccinellidae-tainted Riesling and Pinot noir wine from Germany. J Sci Food Agric. 2015 Feb;95(3):509–14. doi: 10.1002/jsfa.6760. 参考文献:10.1007/s11356-018-2086-z 摘要:Huang X, Huang Z, Chen X, Zhang D, Zhou J, Wang X, Gao N. The predominant phytoplankton of Pseudoanabaena holding specific biosynthesis gene-derived occurrence of 2-MIB in a drinking water reservoir. Environmental Science and Pollution Research. 2018 May 04;25(19):19134–42. doi: 10.1007/s11356-018-2086-z. 参考文献:10.1007/s11356-020-10429-4 摘要:Shen Q, Shimizu K, Miao H, Tsukino S, Utsumi M, Lei Z, Zhang Z, Nishimura O, Asada Y, Fujimoto N, Takanashi H, Akiba M. Effects of elevated nitrogen on the growth and geosmin productivity of Dolichospermum smithii. Environmental Science and Pollution Research. 2020 Aug 15;28(1):177–84. doi: 10.1007/s11356-020-10429-4.