CAS: 2549-14-6; (R)-2-Amino-1-Phenylethan-1-Ol

上下游产品

CAS号604808-44-8 [(R)-cyano(phen... | CAS号134625-72-2 (1R)-2-azido-1-... | CAS号4358-86-5 (+/-)-扁桃酰胺 | CAS号69-96-5 DL-β-苯基丝氨酸 | CAS号56-40-6 甘氨酸 | CAS号145920-96-3 α-phenyl-β-nitr... | CAS号10020-96-9 (R)-(+)-苯乙醇腈 | CAS号111059-46-2 (-)-N-benzoyl-2... | CAS号100-52-7 苯甲醛 | CAS号179930-11-1 (R,E)-2-((苯并[d]... | CAS号88056-92-2 (-)-2-氰基-6-苯恶唑并吡啶

D-扁桃酸置于lithium Aluminium Tetrahydride,乙酰氯体系中,用 四氢呋喃,甲醇 用作溶剂,化学反应生成(R)-α-(氨基甲基)苄醇
参考文献:芳族酮和酮亚胺的有机催化氢化硅烷化中的远程手性诱导.
标题:芳族酮和酮亚胺的有机催化氢化硅烷化中的远程手性诱导.
摘要:
Doi:10.1002/anie.200503941

专利信息

专利号:US-9815771-B2
优先权日:2014-08-06
标题 :Method for the synthesis of mirabegron and its derivatives
发明人：MARQUILLAS OLONDRIZ FRANCISCO; RIEGO ARBOLEYA ESTELA
权利人:INTERQUIM SA
摘要:The present invention refers to a method for the synthesis of a compound of formula (I), solvates, stereoisomers or salts thereof, a key intermediate in the synthesis of Mirabegron by reduction of an amide in the presence of an amine-boranecomplex, wherein the amine is an aniline.

专利号:US-6451727-B2
优先权日:1997-11-12
标题:Catalysts for use in asymmetric synthesis comprising transition metals and chiral amine oxazolinyl ligands
发明人：ZHANG XUMU
权利人:PENN STATE RES FOUND
摘要:The invention is drawn to transition metal catalysts for the practical synthesis of important chiral molecules. The transition metal catalysts comprise chiral ligands based on chiral amine oxazolinyl ligands. The invention includes methods of making the catalysts, and methods of performing reactions using the catalysts.

专利号:US-2018312463-A1
优先权日:2015-10-22
标题:Synthesis of Cyclohexane Carboxamide Derivatives Useful as Sensates in Consumer Products
发明人：YELM KENNETH EDWARD; WOS JOHN AUGUST; BUNKE GREGORY MARK; FREDERICK HEATH; HAUGHT JOHN CHRISTIAN; HOKE STEVEN HAMILTON; SREEKRISHNA KOTI TATACHAR; LIN YAKANG
权利人:PROCTER & GAMBLE
摘要:Synthesis methods to produce a series of carboxamides built off of an (S)-2-amino acid backbone or an (R)-2-amino acid backbone, depending upon the desired diastereomer of the end product.

专利号:US-5856492-A
优先权日:1997-01-10
标题 :Efficient synthesis of a chiral mediator
发明人：CHEN CHENG YI; XU FENG; TILLYER RICHARD D; ZHAO DALIAN
权利人:MERCK & CO INC
摘要:An efficient method for the quantitative preparation and isolation of a compound of formula I ##STR1## or its enantiomer, a chiral mediator used in enantioselective synthesis.

专利号:US-6414180-B1
优先权日:1998-03-04
标 题:Synthesis of chiral β-amino acids
发明人：COLSON PIERRE-JEAN; AWASTHI ALOK K; NAGARAJAN SRINIVASAN R
权利人:SEARLE & CO
摘要:The invention herein is directed to a process for the preparation of chiral beta-amino acids and esters of the formulawherein X and Y are the same or different halo groups, R2 is H or lower alkyl and isomers and pharmaceutically acceptable salts thereof.

专利号:US-5932749-A
优先权日:1996-03-22
标 题:Asymmetric synthesis of R-α-propyl-piperonyl amine and its analogs
发明人：LI HUI-YIN; ANZALONE LUIGI; WALTERMIRE ROBERT EUGENE
权利人:DU PONT PHARM CO
摘要:Processes for the preparation of R- alpha -propyl-piperonyl amine and its analogs, such compounds being useful intermediates in the preparation of elastase inhibitors, and intermediates useful for making R- alpha -propyl-piperonyl amine are described.