CAS: 1633-00-7; 1,6-Diaminohexane-N,N,N',N'-Tetraacetic Acid

相似化合物

1939-36-2 52703-80-7 6245-75-6

上下游产品

1,6-Hexanediamine chloroacetic acid

📜1,6-己二胺,氯乙酸置于sodium Hydroxide体系中,化学反应生成1,6-丙二胺四乙酸
参考文献:六亚甲基二胺四乙酸
标题:六亚甲基二胺四乙酸
摘要:描述了六亚甲基二胺-四乙酸的表示形式,其酸度常数及其与ca 2+的络合物形成常数k K2.还描述了盐na 2 [ca(c 14 H 20 O 8 N 2)]和ca [ca(c 14 H 20 O 8 N 2)]的性质.
Doi:10.1002/hlca.19550380707

专利信息

专利号:US-5446186-A
优先权日:1993-11-09
标 题:Structure and synthesis of nitrophenyl-EGTA, a caged calcium, intermediates thereof and a method of producing a high photochemical yield of liberated calcium
发明人：ELLIS-DAVIES GRAHAM C R; KAPLAN JACK H
摘要:The synthesis and compound of a new caged calcium which is an ortho-nitrophenyl derivative of EGTA and various intermediates. It is synthesized in ten steps and 24% overall yield. The photosensitive chelator, nitrophenyl-EGTA, has a K d for Ca 2+ of 80 nM and for Mg 2+ of 8.8 mM. Upon exposure to ultra-violet light (in the region of 350 nm), the chelator is cleaved, yielding iminodiacetic acid photoproducts with known low Ca-affinity (K d =1 mM). The quantum yield of photolysis of nitrophenyl-EGTA in the presence of Ca a+ is 0.23 and in the absence of Ca 2+ is 0.20. In experiments with chemically skinned skeletal muscle fibers, a fully relaxed fiber equilibrated with nitrophenyl-EGTA:Ca 2+ complex, in the presence of physiological [Mg 2+ ] (i.e. 1.0 mM), produced maximal contraction after a single flash from a frequency doubled ruby laser (347 nm). Half-maximal tension was achieved in 18 ms at 15° C. Nitrophenyl-EGTA provides a new tool for the investigation of the mechanism of Ca 2+ -dependent physiological processes, since under conditions of normal intracellular Ca 2+ and Mg 2+ ions, only Ca 2+ ions are bound by the photolabile chelator and on illumination are released rapidly and in high photochemical yield.

专利号:US-2018312534-A1
优先权日:2015-10-16
标题:Fluorescent anticancer platinum drugs
发明人：SARKAR ARINDAM; MANDAL SWADHIN KUMAR; SENGUPTA ANIRUDDHA; BISWAS GOUTAM; DUTTA PRADIP; SHARMA RUPALI; RAJ JUSTIN PAUL; SURYAVANSHI HEMANT; KUMARI SMITA
权利人:INVICTUS ONCOLOGY PVT LTD
摘要:The present disclosure is in relation to the field of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to fluorescent platinum based compounds. The disclosure further relates to synthesis of said fluorescent platinum based compounds, nanoparticles and compositions comprising said fluorescent platinum based compounds/nanoparticles. The disclosure also relates to methods of managing cancer by the fluorescence changes between aforesaid platinum based compounds and corresponding free ligands, nanoparticles and compositions.

专利号:US-11744248-B2
优先权日:2017-08-20
标 题:Disinfectant composition for control of clostridium difficile spore
发明人：SMYTH BRUCE; BRALKOWSKI MICHAEL
权利人:SMYTH BRUCE; BRALKOWSKI MICHAEL; ENVIRO SPECIALTY CHEMICALS INC
摘要:A composition and method for inducing and inflicting damage to cell membranes of microorganism by inducing changes in membrane permeability caused by polycation-induced membrane pores. The control of Clostridium difficile spores with an efficacy of 99.99% on hard surfaces is provided. The invention includes the application of an evaporation-induced self-assembly, surfactant-mediated synthesis or self-condensing polymer, which forms a film which is both flexible on the surface as a nano-polymeric coating and with refractive index yielding a transparent coating. The polymeric matrix includes various biocidal polymeric cationic quaternary salts, one being a silyl quaternary having a kinetic zeta potential to disrupt bacterial spores functions. The polymeric matrix consist of multiple small molecule biocides as well as polymerics biocide combinations not otherwise seen to develop an surface topography of peaks and troughs in the nano range to resist bacterial adhesion factors and subsequent biofilm formation. The surfactants induce self-assembly film topography.

专利号:WO-2013073774-A1
优先权日:2011-11-17
标 题:Development of nucleic acid gel matrix for cell-free protein synthesis of cell nucleus replicate, and method for producing same

专利号:CN-106830089-A
优先权日:2017-02-22
标题:Synthesis of spinel color ceramic pigments containing cobalt and its application in the preparation of solar light-absorbing coatings

专利号:CN-110474059-B
优先权日:2018-05-11
标题 :Method for solid-phase macro synthesis of non-noble metal oxygen reduction catalyst, catalyst and application thereof