CAS: 85006-31-1; Methyl 3-Amino-4-Methylthiophene-2-Carboxylate

上下游产品

CAS号2689-70-5 4-甲基-3-氧代四氢噻吩-2-甲酸甲酯 | CAS号125089-02-3 4-甲基-3-氨基二氢噻吩-2-甲酸甲酯 | CAS号35265-83-9 2,4-二氯-7-甲基噻吩并[... | CAS号23968-18-5 3-氨基-4-甲基-2-噻吩羧酸 | CAS号35265-81-7 7-甲基噻吩并[3,2-D]嘧... | CAS号35265-88-4 4-(2-氯-7-甲基噻吩并[... | CAS号1356016-35-7 2-chlorothieno[... | CAS号1356016-36-8 2-chlorothieno[... | CAS号175137-10-7 3-二甲基氨基-4-甲基-2-羧酸甲酯 | CAS号1269667-57-3 4-氯噻吩并[3,2-d]嘧啶-7-羧酸 | CAS号229342-86-3 3-氯-4-甲基噻吩-2-羧酸 | CAS号175137-21-0 4-氯-7-甲基噻吩并[3,2-D]嘧啶

4-甲基-3-氨基二氢噻吩-2-甲酸甲酯置于双氧水体系中,用 乙酸乙酯,异丙醇 作为反应溶剂,化学反应生成 3-氨基-4-甲基噻吩-2-甲酸甲酯
参考文献:Process For The Preparation Of Thiophene Derivatives And Also New
标题:Process For The Preparation Of Thiophene Derivatives And Also New
摘要:制备噻吩衍生物及新的二氢噻吩1-氧化物的过程.在噻吩环上具有-可选择取代的-氨基基团的噻吩衍生物是通过使用h.Sub.2 O.Sub.2将以与所需噻吩衍生物相同的方式取代的二氢噻吩脱氢制备的,二氢噻吩在中性介质中与h.Sub.2 O.Sub.2在第一反应阶段反应,反应生成相应的亚砜,然后在第二反应阶段通过酸催化重排成噻吩衍生物.在此反应中形成的二氢噻吩1-氧化物是新化合物.像通过酸重排形成的噻吩衍生物一样,它们也是中间体,主要用于植物保护剂和药物领域.

专利信息

专利号:US-8329923-B2
优先权日:2010-06-17
标 题:4, 4′ disubstituted 4H-cyclopentadithiophene and new methods for synthesizing the same
发明人：VANDERZANDE DIRK; LUTSEN LAURENCE; VAN MIERLOO SARAH
权利人:VANDERZANDE DIRK; LUTSEN LAURENCE; VAN MIERLOO SARAH; IMEC; UNIV HASSELT
摘要:The present preferred embodiments relate to a method for the synthesis of a compound having the following general formula: n nthe method comprising the step of reacting, in presence of a diprotic acid having a negative pKa, a compound having the general formula:n n nwherein R 1 and R 2 are organic groups and wherein X and Y are independently selected from the group consisting of hydrogen, chloro, bromo, iodo, boronic acid, boronate esters, borane, pseudohalogen and organotin. It further relates to compounds so obtained and to compounds resulting from the ring closure of compound (II).

专利号:US-4670560-A
优先权日:1986-04-28
标 题:Thienopyrimidine-2,4-dione derivatives and intermediates thereof
发明人：PRESS JEFFERY B; RUSSELL RONALD K
权利人:ORTHO PHARMA CORP
摘要:The synthesis of thienopyrimidine-2,4-dione derivatives and their urea intermediates is described. The novel urea intermediates and thienopyrimidine-2,4-dione derivatives are generally vasodilating agents and anti-hypertensive agents. The compounds are useful as cardiovascular agents.

专利号:US-4707550-A
优先权日:1986-04-28
标题 :N-(substituted thienyl)-N'-(substituted piperazinyl)-ureas
发明人：PRESS JEFFERY B; RUSSELL RONALD K
权利人:ORTHO PHARMA CORP
摘要:The synthesis of thienopyrimidine-2,4-dione derivatives and their urea intermediates is described. The novel urea intermediates and thienopyrimidine-2,4-dione derivatives are general vasodilating agents and anti-hypertensive agents. The compounds are useful as cardiovascular agents.

专利号:RU-2184730-C1
优先权日:2001-05-16
标 题 :Method of synthesis of 4-methyl-3-[2-(n-propyl- -amino)propionylamino]thiophene-2-carboxylic acid methyl ester hydrochloride

专利号:CN-106699724-B
优先权日:2017-01-05
标题:A method of recycling articaine hydrochloride or in which product from synthesis mother liquid