CAS: 6937-16-2; Ethyl 4-Aminobutanoate Hydrochloride

该化合物是乙基-氨基丁酸盐衍生物盐,通常用于有机合成和制药研究,该化合物是制备GABA(氨基丁酸)模拟分子和其他生物活性分子的多用途中间体,其盐酸形式增强稳定性和溶性,便利处理和反应效率,该酯允许进一步功能化,使其对衍生研究具有价值.该产品具有高纯度和一贯性,确保合成应用的可靠结果.该化合物在药用化学,特别是在与CNS有关的研究中,其作用凸显了其作为药物发现和开发基石的重要性.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号228110-66-5 ethyl 4-[(2-met... | CAS号64-17-5 乙醇 | CAS号56-12-2 4-氨基丁酸 | CAS号90670-73-8 2H-Pyrrole, 5-e... | CAS号931-46-4 2-ethoxyprrole | CAS号106508-62-7 4-异氰酸基丁酸乙酯 | CAS号57294-38-9 N-B°C-γ-氨基丁酸 | CAS号17126-65-7 4-异硫代氰酰基丁酸乙酯 | CAS号228110-66-5 ethyl 4-[(2-met... | CAS号999-10-0 4-羟基丁酸乙酯 | CAS号340962-88-1 1-(1-苄基哌啶-4-基)吡... | CAS号13031-62-4 盐酸加巴胺(4-氨基丁酰胺盐酸盐) | CAS号56-12-2 4-氨基丁酸 | CAS号101961-98-2 4-[[(4-Phenyl-2... | CAS号554-68-7 三乙胺盐酸盐

合成工艺路线路线简述

    2-乙氧基-4,5-二氢-3H-吡咯置于盐酸,水体系中,用 乙醚 作为反应溶剂,化学反应 10.08H,反应生成 4-氨基丁酸乙酯.盐酸盐
    参考文献:Menezes,Royce; Smith,Michael B.,Synthetic Communications,1988,Vol. 18,# 4,P. 1625-1636
    标题:Menezes,Royce; Smith,Michael B.,Synthetic Communications,1988,Vol. 18,# 4,P. 1625-1636

    海关参考信息

    专利信息


    专利号:EP-1567195-B1
    优先权日:2002-11-26
    标题 :Dendrimer conjugates for selective solubilisation of protein aggregates
    发明人:HEEGAARD PETER; BOAS ULRIK
    权利人:UPFRONT CHROMATOGRAPHY AS
    摘要:Dendrimer conjugates are presented, which are formed between a dendrimer and a protein solubilising substance. Such dendrimer conjugates ar effective in the treatment of protein aggregate-related diseases (e.g. prion-related diseases). The protein solubilising substance and the dendrimer together show a protein aggregate solubilising effect higher than a physical mixture of the dendrimer and the protein solubilising substance (i.e. a synergistic effect). Such dendrimer conjugates are useful in the treatment or prevention of protein aggregate-relates diseases, in disinfection/decontamination processes and in classifying or identifying protein aggregates. The synthesis of such dendrimer conjugates from readily-available starting materials is described.

    专利号:US-8580822-B2
    优先权日:2006-12-11
    标 题:Compositions, synthesis, and methods of using indanone based cholinesterase inhibitors
    发明人:BHAT LAXMINARAYAN; MOHAPATRA PRABHU PRASAD
    权利人:BHAT LAXMINARAYAN; MOHAPATRA PRABHU PRASAD; REVIVA PHARMACEUTICALS INC
    摘要:The present invention provides novel indanone derivatives which can be advantageously used for treating and/or preventing of a medical condition for which inhibition of a cholinesterase is desired.

    专利号:US-7737166-B2
    优先权日:2005-08-17
    标 题:Antifungal bicyclic hetero ring compounds
    发明人:KAWAKAMI KATSUHIRO; KANAI KAZUO; HORIUCHI TAKAO; TAKESHITA HIROSHI; KOBAYASHI SYOZO; SUGIMOTO YUICHI; ACHIWA ISSEI; KUROYANAGI JUNICHI
    权利人:DAIICHI SANKYO CO LTD
    摘要:A 1,6-β-glucan synthetase inhibitor is provided, having potent growth inhibition and having excellent safety. A compound is provided, capable of expressing in a wide spectral range and specifically or selectively, an antifungal effect based on its functional mechanism of 1,6-β-glucan synthesis inhibition. Also provided is a drug, a salt or hydrate thereof, especially an antifungal that contains the compound. Concretely, provided is a compound of the following formula (I), its salt or hydrate, and a drug or antifungal containing, as the active ingredient, the compound, its salt or hydrate:

    专利号:US-2008153878-A1
    优先权日:2006-12-11
    标题:Compositions, synthesis, and methods of using indanone based cholinesterase inhibitors

    专利号:US-8247563-B2
    优先权日:2006-12-11
    标题 :Compositions, synthesis, and methods of using indanone based cholinesterase inhibitors

    专利号:US-2012252842-A1
    优先权日:2006-12-11
    标题 :Compositions, synthesis, and methods of using indanone based cholinesterase inhibitors
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    主要参考文献

    参考标题:Total Synthesis Of Fontanesine B And Its Isomer: Their Antiproliferative Activity Against Human Colorectal Cancer Cells
    作者:Takumi Abe,Tomoki Itoh,Masaru Terasaki |发布日期:2019.7
    摘要:A Concise Synthesis Of Pyrano[3,2‐e]Indole Alkaloid Fontanesine B By A Fischer Indolization Is Described. This Key Fischer Indolization Starts With The Pyran‐ring And Alkene Intact, Facilitating Potential Synthetic Applications. Furthermore, Fontanesine B And Its Isomer Were Evaluated For In Vitro Antiproliferative Activity Against Human Colorectal Cancer Cells. The Isomer Of Fontanesine B Showed Higher

    合成参考文献


    摘要:Dissertationes Pharmaceuticae et Pharmacologicae., 18(229), 1966
    摘要:Archives Internationales de Pharmacodynamie et de Therapie., 145(233), 1963 []
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