CAS: 561-95-5; Nimbiol
- 英文名称Nimbiol
- 中文名称12-羟基-13-甲基罗汉松-8,11,13-三烯-7-酮
- 其它别名9(1H)-Phenanthrenone,2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a,7-tetramethyl-, (4aS-trans)-; Nimbiol (6CI,7CI); Pod°Carpa-8,11,13-trien-7-one, 12-hydroxy-13-methyl- (8CI); (+)-Nimbiol; Nimbial
- CAS编号561-95-5
- FDA UNII编号:946NA6450V
- 分子式:C18H24O2分子量:272.38
- 产品CID: 2677292
- 产品分类有机原料 → 脂质和类脂质分子 → 异戊烯醇脂质
MSDS等安全信息
上下游产品
(+/-)-Nimbiol Methyl Ether 3772-54-115,16-Dinorpimara-8,11,13-Trien-12-Ol 72444-79-2
Formic Acid (4Bs,8As)-2,4B,8,8-Tetramethyl-4B,5,6,7,8,8A,9,10-Octahydro-Phenanthren-3-Yl Ester 206554-13-4
(4Bs,8As)-2,4B,8,8-Tetramethyl-4B,5,6,7,8,8A,9,10-Octahydro-Phenanthrene-3-Carbaldehyde 206554-12-3
(+)-(5S,10S)-13-Methylpodocarpa-8,11,13-Triene 57706-44-2
(4Bs,8As)-2,4B,8,8-Tetramethyl-4B,5,6,7,8,8A,9,10-Octahydro-Phenanthrene-3-Carboxylic Acid Methyl Ester 165619-89-6
((4Bs,8As)-2,4B,8,8-Tetramethyl-4B,5,6,7,8,8A,9,10-Octahydro-Phenanthren-3-yl)-Methanol 206554-11-2
合成工艺路线路线简述
📜(+)-(5S,10S)-13-Methylpodocarpa-8,11,13-Triene置于四氯化锡 Sodium Chromate(Vi),Urea-Hydrogen Peroxide,乙酸酐,Potassium Carbonate,三氟乙酸酐体系中,用 甲醇,水,溶剂黄146 作为反应溶剂,化学反应 27.4H,反应生成 12-羟基-13-甲基罗汉松-8,11,13-三烯-7-酮
参考文献:Highly Efficient Synthesis Of (+)-Nimbiol And Other Podocarpanes Derivatives From Sclareol
标题:Highly Efficient Synthesis Of (+)-Nimbiol And Other Podocarpanes Derivatives From Sclareol
摘要:该研究开辟了以荚果烷为骨架的三环二萜的新途径,总体收率极高,并实现了从仙客来醇到 (+)-Nimbiol 的高效合成.
DOI:10.1055/s-2007-982533
海关参考信息
- 2902600000-乙苯
2902700000-异丙基苯
2912110000-甲醛
2912120000-乙醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Facile Access To Optically Active Ring C Aromatic Diterpene Derivatives From Manool. Highly Efficient Syntheses Of (+)-12-Methyl-7-Oxo-Podocarpa-8,11,13-Triene-13-Carboxylic Acid, (+)-13-Methyl-7-Oxopodocarpa-8,11,13-Triene-12-Carboxylic Acid And (+)-Nimbiol作者:Tatsuhiko Nakano,Randolph Alonso,María Aracelis Maillo,Alfonso Martín,Ramona Avila Núñez
摘要:The Extension Of Our Recently Developed Strategy Using The Key Intermediate 2, Obtainable In Two Steps (52% Overall Yield) From Manool 1, To The Synthesis Of Naturally Occurring Ring C Aromatic Diterpene Derivatives Provides In Three Steps (+)-12-Methyl-7-Oxopodocarpa-8,11,13-Triene-13-Carboxylic Acid 4B And Its Isomer 6B, And In Seven Steps (+)-Nimbiol 11B, In Good Overall Yields. This Synthesis Discloses That The Structure 4B Assigned To Margolone Isolated From Azadirachta Indica A. Juss Is Incorrect And Needs To Be Reinvestigated.
合成参考文献
参考文献:10.1016/0040-4020(60)85006-5
摘要:Sengupta P, Choudhuri SN, Khastgir HN. Constituents of the trunk bark of Melia azadirachta Linn. and the structure of the ketophenol, nimbiol. Tetrahedron. 1960 Jan;10(1-2):45–54. doi: 10.1016/0040-4020(60)85006-5.
📝 需求与反馈
尽可能描述清楚需求与问题信息
