CAS: 490-31-3; 3,7-Dihydroxy-2-(3,4,5-Trihydroxyphenyl)-4H-Chromen-4-One

该化合物是属于氟拉富诺醇类的氟拉夫诺类化合物,其特征是黄色晶状表面,主要见于各种植物,特别是叶子和花卉中.化学学上,它以其抗氧化特性著称,它有助于其潜在的健康利益,包括防炎和抗癌影响.Robinetin的分子配方包括多种氢化物组,它加强了极地溶剂的再活性和溶性.其结构是氟拉夫尼骨干,它是一种在氟拉夫尼类中很常见,允许它参与各种生物化学相互作用.此外,由于它的生物活性特性,对Robinetin在植物色化中的作用及其在食品和制药工业的潜在应用进行了研究.

结构式图片

上下游产品

Robinetin trimethyl ether 3,7,3'-trimethoxy-4',5'-dihydroxyflavone 7-hydroxy-3-methoxy-2-(3,4,5-trimethoxy-phenyl)-chromen-4-one Dihydrorobinetin3,7,3',4',5'-O-pentamethylrobinetin 3,7-diacetoxy-2-(3,4,5-triacetoxy-phenyl)-chromen-4-one

合成工艺路线路线简述

  • 合成目标产物 Robinetin 主要起始原料 Paeonol
  • (文献来源)合成步骤主要原料 Paeonol
📜1-(2,4-二羟基苯基)-2-甲氧基-1-乙酮置于氢碘酸,乙酸酐,Sodium 3,4,5-Trimethoxybenzoate体系中,化学反应生成 洋槐黄素
参考文献:73.花青素.第十三部分.刺槐(robinia Pseudacacia)色素的合成
标题:73.花青素.第十三部分.刺槐(robinia Pseudacacia)色素的合成
摘要:
DOI:10.1039/jr9330000268

海关参考信息

专利信息


专利号:US-2007232495-A1
优先权日:2006-03-24
标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

专利号:US-9889098-B2
优先权日:2009-10-22
标题:Methods of making and using compositions comprising flavonoids
发明人:BIRBARA PHILIP J
权利人:BIRBARA PHILIP J; VIZURI HEALTH SCIENCES LLC
摘要:The subject invention relates to novel micoparticulate and soluble forms of flavonoids, and their synthesis. The invention also includes novel formulations of such flavonoids. Further, the invention includes novel methods of manufacturing the flavonoid formulations. The invention also relates to a wide variety of applications of the flavonoid formulations.

专利号:WO-0007607-A1
优先权日:1998-08-04
标 题:Nutrient and therapeutic compositions for the treatment of cancer
权利人:KOSBAB JOHN V
摘要:This invention relates to nutrient and therapeutic compositions for the treatment of cancer symptoms and conditions. Compositions of this invention contain a mixture of antioxidants, components that promote collagen maintenance and synthesis, components that regulate blood lipids, glucose and/or insulin, and lower homocysteine levels. Compositions also provide supplementation for nutrient (vitamin, mineral and cofactor) deficiencies to restore and maintain normal biochemical function. Cancer formulations, particularly those adapted for treatment of female cancers, can be combined with components that provide benefit in osteoporosis.

专利号:US-2727890-A
优先权日:1953-03-02
标 题 :Synthesis of an aldohexoside of a flavonol
发明人:WENDER SIMON H; ICE CLARK H
权利人:WENDER SIMON H; ICE CLARK H

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献


1: Cushnie TP, Lamb AJ. Antimicrobial activity of flavonoids. Int J Antimicrob Agents. 2005 Nov;26(5):343-56. doi: 10.1016/j.ijantimicag.2005.09.002. Erratum in: Int J Antimicrob Agents. 2006 Feb;27(2):181.
2: Menacer R, Rekkab S, Kabouche Z. Fisetin and Robinetin antiradical activity under solvent effect: density functional theory study. J Mol Model. 2022 Aug 1;28(8):240. doi: 10.1007/s00894-022-05223-7. 32(2):214-223. doi: 10.4062/biomolther.2023.061. Epub 2024 Feb 1.
4: Birt DF, Walker B, Tibbels MG, Bresnick E. Anti-mutagenesis and anti- promotion by apigenin, robinetin and indole-3-carbinol. Carcinogenesis. 1986 Jun;7(6):959-63. doi: 10.1093/carcin/7.6.959. Erratum in: Carcinogenesis 1986 Sep;7(9):1619. 89(2-3):88-97. doi: 10.1016/j.jphotobiol.2007.09.001. Epub 2007 Sep 19.

合成参考文献


参考文献:10.1021/np50001a002
摘要:Edwards JM, Raffauf RF, Le Quesne PW. Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones. J Nat Prod. 1979 Jan;42(1):85–91. doi: 10.1021/np50001a002.
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