CAS: 357335-87-6; Brivaracetam

英文名称Brivaracetam
中文名称布瓦西坦外消旋体
CAS编号357335-87-6
MFCD编号:MFCD24641474
分子式:C11H20N2O2分子量:212.29
产品CID: 1366048
产品分类分析化学 → 标准品 → 药典标准品和杂质标准品

相似结构搜索
InChIKey: MSYKRHVOOPPJKU-UHFFFAOYSA-N
1S/C11H20N2O2/c1-3-5-8-6-10(14)13(7-8)9(4-2)11(12)15/h8-9H,3-7H2,1-2H3,(H2,12,15)
计算化学: 氢键受体数2.0氢键供体数1.0可旋转键数5.0

MSDS等安全信息

警示词warning
危险描述H303 May be harmful if swallowed+H313 Skin contact may be harmful+H333 Inhalation may be harmful to the body
防范说明P264Thoroughly clean after treatmentP280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective maskP305If it enters the eyesP351Rinse carefully with water for a few minutesP338Remove the contact lens(If any)And easy to operate,Continue flushingP337If eye irritation persistsP313Obtain medical advice/care
安全声明H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body

合成工艺路线路线简述

📜(Alphas)-Alpha-乙基-2,5-二氢-2-氧代-4-丙基-1H-吡咯-1-乙酰胺反应生成布瓦西坦,布瓦西坦外消旋体
参考文献: 2-Oxo-1-Pyrrolidine Derivatives,Processes For Preparing Them And Their Uses[fr] Derives De 2-Oxo-1-Pyrrolidine,Procedes De Preparation Et Utilisations Desdits Derives
标题: 2-Oxo-1-Pyrrolidine Derivatives,Processes For Preparing Them And Their Uses[fr] Derives De 2-Oxo-1-Pyrrolidine,Procedes De Preparation Et Utilisations Desdits Derives
摘要:本发明涉及式(i)的2-氧代-1-吡咯烷衍生物,其中取代基如规范中所定义,以及它们作为药物的用途.本发明的化合物特别适用于治疗癫痫等神经系统疾病.