CAS: 316-46-1; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-yl)-5-Fluoropyrimidine-2,4(1H,3H)-Dione

相似化合物

3094-09-5 3094-09-5 58-96-8

上下游产品

尿嘧啶核苷 Uridine 58-96-8
2'-O-(4-Carboxybutyryl)-5-Fluorouridine 163680-83-9
5-Fluoro-1-(5′-O-Trityl-β-D-Ribofuranosyl)Uracil 3871-66-7
5-氟胞嘧啶核苷 5-Fluorocytidine 2341-22-2
5-甲基尿甙 5-Methyluridine 1463-10-1
5-溴尿苷 5-Bromouridine 957-75-5
1-(2,3,5-Tri-O-Benzoyl-β-D-Ribofuranosyl)-5-Fluoro-Uracil 2560-60-3
胞苷 Cytidine 65-46-3
[1-[[[(2R,3S,4R,5R)-5-(5-Fluoro-2,4-Dioxopyrimidin-1-yl)-3,4-Dihydroxyoxolan-2-Yl]Methoxy-Hydroxyphosphoryl]Oxy-Hydroxyphosphoryl]-1-Hydroxyethyl]Phosphonic Acid 464169-57-1
腺苷 Adenosine 58-61-7

胞苷 以46.6%的收率获得产物5-氟尿嘧啶核苷
参考文献:Process For Production Of 5-Fluorouracil And Its Derivatives
标题:Process For Production Of 5-Fluorouracil And Its Derivatives
摘要:生产5-氟尿嘧啶及其衍生物的方法包括在水性介质中将具有以下结构的胞嘧啶化合物:##str1## 其中r是氢原子或糖苷基与氟或氟磺酸氟酸酯(foso.Sub.2 F)反应,以得到相应的具有以下结构的5-氟尿嘧啶化合物:##str2## 其中r如上所定义.

专利信息

专利号:US-12146136-B2
优先权日:2020-03-26
标题:Synthesis of modified oligonucleotides with increased stability
发明人：KHVOROVA ANASTASIA; ROUX LOÃ?C MAURICE RENÉ JEAN; YAMADA KEN
权利人:UNIV MASSACHUSETTS
摘要:This disclosure relates to the synthesis of novel modified oligonucleotides. The synthesis of novel phosphoramidites are also provided.

专利号:US-11858953-B2
优先权日:2018-04-04
标 题:Compositions and methods for synthesis of phosphorylated molecules
发明人：CHAPUT JOHN; LIAO JEN-YU; BALA SAIKAT
权利人:UNIV CALIFORNIA
摘要:The invention provides compositions and methods for synthesis of phosphorylated organic compounds, including nucleoside triphosphates.

专利号:US-6818633-B2
优先权日:2001-06-29
标题:Antiviral compounds and methods for synthesis and therapy
发明人：BALZARINI JAN M R; DE CLERCQ ERIK D A; HOLY ANTONIN
权利人:ACAD OF SCIENCE CZECH REPUBLIC; REGA STICHTING
摘要:Novel compounds are provided having formula (I)whereR1, R2, R3, R4, Z, X and * are defined herein. Also provided are antiviral methods for use and processes for synthesis of the compounds of formula (I).

专利号:US-8785629-B2
优先权日:2009-06-18
标题 :Phosphonates synthons for the synthesis of phosphonates derivatives showing better bioavailability
发明人：AGROFOGLIO LUIGI A; ROY VINCENT; PRADERE UGO
权利人:AGROFOGLIO LUIGI A; ROY VINCENT; PRADERE UGO; CENTRE NAT RECH SCIENT; UNIV ORLEANS
摘要:Synthons for the synthesis of phosphonates prodrugs POM and POC, especially for direct Cross Metathesis.

专利号:WO-2022080234-A1
优先权日:2020-10-12
标 题 :Method for modifying genome of algae belonging to genus galdieria
发明人：KOKUBUN Yume; YAMASAKI HIROAKI; MIYAGISHIMA SHIN-YA; HIROOKA Shunsuke; FUJIWARA TAKAYUKI
权利人:DAINIPPON INK & CHEMICALS; INTER UNIV RESEARCH INSTITUTE CORPORATION RESEARCH ORGANIZATION OF INFORMATION AND SYSTEMS
摘要:Provided are: a method for modifying the genome of algae belonging to the genus Galdieria, comprising a step for carrying out genome modification on a haploid form of algae belonging to the genus Galdieria; a method for producing genome-modified algae belonging to the genus Galdieria, comprising a step for carrying out genome modification of algae belonging to the genus Galdieria using the genome modification method; a method for producing a desired substance or food, which uses algae belonging to the genus Galdieria obtained using the production method; and algae belonging to the genus Galdieria, that has a mutation in a gene that participates in the synthesis of a nutrient component and that has a requirement for the nutrient component.

专利号:US-2024384319-A1
优先权日:2021-09-17
标题 :Synthesis of Oligonucleotides
发明人：LOVELOCK SARAH
权利人:UNIV MANCHESTER
摘要:The present invention relates to a novel method for oligonucleotide synthesis, using a catalytic primer-template, e.g. a hairpin primer, to achieve multiple rounds of oligonucleotide synthesis and dissociation from the template in the same reaction, such that at the end of the reaction the amount of oligonucleotide generated is greater than the amount of template provided in the reaction. The primer contains a cleavable site and the reaction is carried out in a single mixture with a cleavage agent. The cleavable site may be an inosine and the agent an endonuclease V.