CAS: 195-19-7; Benzo[c]Phenanthrene

该化合物是一种多环芳烃(PAH),其特点是由苯并呋喃和另外的苯环衍生的四环结构结合而成,该化合物由于硬性,平面几何学和扩展的同质,有助于其稳定性和电子特性,因此对有机化学和材料科学具有重大兴趣; 苯并苯并呋喃是合成包括染料,药品和光电子材料在内的复杂有机分子的宝贵中间体; 其高热稳定性和接受选择性功能化的能力使其成为先进化学应用的多功能建筑块; 研究人员还研究其环境持久性和潜力,作为PAH相关研究的模型化合物.

结构式图片

相似化合物

89523-51-3 2606-85-1 652-04-0

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

2-hydroxybenzo[c]phenanthrene c]phenanthrene-5,6-dicarboxylic acid-anhydridebenzo[c]phenanthrene-5,6-dicarboxylic acid-anhydride 1.2.9.10.11.12-Hexahydro-3.4-benzophenanthren 9,10-dihydro-3,4-benzophenanthrenephenanthrene 5,6-dionebenzophenanthrene 5,6-dione 5-acetylbenzo[c]phenanthrene 5-formylbenzo[c]phenanthrene benzo[ghi]fluoranthene

合成工艺路线路线简述

    3,4-二氢-1-苯基萘置于barium Dihydroxide,铁粉,铜体系中,化学反应生成苯并-3,4-菲
    参考文献:The Synthesis Of Polynuclear Aromatic Hydrocarbons. Ii. Methylbenzo (C) Phenanthrenes1
    标题:The Synthesis Of Polynuclear Aromatic Hydrocarbons. Ii. Methylbenzo (C) Phenanthrenes1
    摘要:
    Doi:10.1021/ja01098A026

    海关参考信息

    专利信息


    专利号:US-2003162992-A1
    优先权日:2001-12-14
    标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
    发明人:WATANABE KYOICHI A; DU JINFA
    摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

    专利号:US-7211172-B1
    优先权日:2002-08-29
    标 题 :Method of photochemical synthesis of vitamin Ds
    发明人:SALTIEL JACK
    权利人:UNIV FLORIDA STATE RES FOUND
    摘要:An enhanced photochemical method of making vitamin D includes irradiating a reaction mixture of precursor molecules with light having a wavelength of 254 nm and with light having a wavelength of 313 nm to produce previtamin D, and is followed by heating at a temperature not exceeding 100° C. to convert previtamin D to vitamin D.

    专利号:EP-0182609-B1
    优先权日:1984-11-15
    标 题:Polycyclic biocidal compounds, their synthesis, formulations containing them
    摘要:The invention relates to biocidal compounds of the formula RCH2NHR<1> or monomethyl or monoethyl ethers thereof, the compounds including the said ethers containing no more than 30 carbon atoms in total; esters thereof; salts thereof; wherein R = C15-22 carbocyclic fused ring system containing 3-5 aromatic rings optionally substituted by 1-2 substituents, said substituents (containing n = 0-2 and R<2> is C1-2 alkyl optionally substituted by OH or C1-2 alkoxy; or R is optionally substituted by NR<3>R<4> (which contains and R<4> = C1-3 alkyl group or NR<3>R<4> forms a 5- or 6- membered heterocyclic ring optionally containing 1-2 additional heteroatoms; R<1> contains wherein m is 0 or 1; R<5> and R<6> = H or C1-5 alkyl optionally substituted by OH; R<7> and R<8> = H, C1-3 alkyl; -@@@-is a five-or-six-membered saturated carbocyclic ring; R<9> is H, CH3 or CH2OH; R<1><0>, R<1><1> and R<1><2> = H or CH3; R<1><3> = H, CH3, OH or CH2OH with the proviso that R is not substituted or unsubstituted perylene, fluoranthene, chrysene, pyrene or triphenylene. Also disclosed are formations containg the compounds, methods for their preparation, chemical intermediates in their preparation and the use of the compounds in the treatment of tumors and an antipathogenic agents particularly antifungal agents.

    专利号:CA-2470202-A1
    优先权日:2001-12-14
    标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides

    专利号:WO-03051298-A2
    优先权日:2001-12-14
    标 题:Preparation of intermediates useful in the synthesis of antiviral nucleosides

    专利号:EP-1461041-A4
    优先权日:2001-12-14
    标 题:PREPARATION OF INTERMEDIATES SUITABLE FOR THE SYNTHESIS OF ANTIVIRAL NUCLEOSIDES
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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: A Pal, Et Al. C-Terminal Region Amino Acid Substitutions Contribute To Catalytic Differences Between Murine Class Alpha Glutathione Transferases Mgsta1-1 And Mgsta2-2 Toward Anti-Diol Epoxide Isomers Of Benzo[参考文献]: Cédric Brulé, Et Al. Structure/reactivity Relationships In The Benzo[参考文献]: I Pontén, Et Al. Influence Of Adduct Position And Sequence Length On The Ligation Of Oligonucleotides Containing Benzo[参考文献]: Jianxin Wu, Et Al. In Vitro And In Vivo Modulations Of Benzo[参考文献]: Katrina W Brown, Et Al. Benzo[a]Pyrene And Benz[c]Phenanthrene: The Effect Of Structure On The Binding Of Water Molecules To The Diol Epoxides. Chem Res Toxicol. 2002 Aug;15(8):1069-79.

    合成参考文献


    摘要:Stará, I. G.; Starý, I., Science of Synthesis, (2010) 45, 896.
    摘要:Stará, I. G.; Starý, I., Science of Synthesis, (2010) 45, 885.
    摘要:Melkonyan, F. S.; Gevorgyan, V., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 1, 8.
    摘要:Zhang, L., Science of Synthesis: Metal-Catalyzed Cyclization Reactions, (2016) 1, 294.
    参考文献:10.1021/bi060158h
    摘要:Yakovleva L, Handy CJ, Yagi H, Sayer JM, Jerina DM, Shuman S. Intercalating polycyclic aromatic hydrocarbon-DNA adducts poison DNA religation by Vaccinia topoisomerase and act as roadblocks to digestion by exonuclease III. Biochemistry. 2006 Jun 20;45(24):7644–53. doi: 10.1021/bi060158h.
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