专利号:US-2003162992-A1 优先权日:2001-12-14 标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides 发明人:WATANABE KYOICHI A; DU JINFA 摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.
专利号:US-7211172-B1 优先权日:2002-08-29 标 题 :Method of photochemical synthesis of vitamin Ds 发明人:SALTIEL JACK 权利人:UNIV FLORIDA STATE RES FOUND 摘要:An enhanced photochemical method of making vitamin D includes irradiating a reaction mixture of precursor molecules with light having a wavelength of 254 nm and with light having a wavelength of 313 nm to produce previtamin D, and is followed by heating at a temperature not exceeding 100° C. to convert previtamin D to vitamin D.
专利号:EP-0182609-B1 优先权日:1984-11-15 标 题:Polycyclic biocidal compounds, their synthesis, formulations containing them 摘要:The invention relates to biocidal compounds of the formula RCH2NHR<1> or monomethyl or monoethyl ethers thereof, the compounds including the said ethers containing no more than 30 carbon atoms in total; esters thereof; salts thereof; wherein R = C15-22 carbocyclic fused ring system containing 3-5 aromatic rings optionally substituted by 1-2 substituents, said substituents (containing = 4 carbon atoms in total) being halogen; cyano; C1-4 alkyl or C1-4 alkoxy, each optionally substituted by OH or C1-2 alkoxy; halogen substituted C1-2 alkyl or C1-2 alkoxy; S(O)nR<2> n = 0-2 and R<2> is C1-2 alkyl optionally substituted by OH or C1-2 alkoxy; or R is optionally substituted by NR<3>R<4> (which contains = 5 carbons) wherein R<3> and R<4> = C1-3 alkyl group or NR<3>R<4> forms a 5- or 6- membered heterocyclic ring optionally containing 1-2 additional heteroatoms; R<1> contains = 8 carbons and is wherein m is 0 or 1; R<5> and R<6> = H or C1-5 alkyl optionally substituted by OH; R<7> and R<8> = H, C1-3 alkyl; -@@@-is a five-or-six-membered saturated carbocyclic ring; R<9> is H, CH3 or CH2OH; R<1><0>, R<1><1> and R<1><2> = H or CH3; R<1><3> = H, CH3, OH or CH2OH with the proviso that R is not substituted or unsubstituted perylene, fluoranthene, chrysene, pyrene or triphenylene. Also disclosed are formations containg the compounds, methods for their preparation, chemical intermediates in their preparation and the use of the compounds in the treatment of tumors and an antipathogenic agents particularly antifungal agents.
专利号:CA-2470202-A1 优先权日:2001-12-14 标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
专利号:WO-03051298-A2 优先权日:2001-12-14 标 题:Preparation of intermediates useful in the synthesis of antiviral nucleosides
专利号:EP-1461041-A4 优先权日:2001-12-14 标 题:PREPARATION OF INTERMEDIATES SUITABLE FOR THE SYNTHESIS OF ANTIVIRAL NUCLEOSIDES
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合成参考文献
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