CAS: 1868-53-7; Dibromofluoromethane

上下游产品

Bromoform dibromofluoroacetic acid dibromofluoromethyltriphenylphosphonium bromide brominesodium formate Methyl fluoride bromofluoromethane (2-bromo-2-fluor°Cyclopropane-1,1-diyl)dibenzene

氟三溴甲烷置于三苯基膦,锌体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应 0.75H,以56%的收率获得二溴氟甲烷
参考文献:氟化phospho叶立德:氢氟烃合成中的多种原位wittig中间体
标题:氟化phospho叶立德:氢氟烃合成中的多种原位wittig中间体
摘要:已经开发了一种简单方便的技术来合成,表征和分离氢氟/氢卤代碳氢化合物,例如氯二氟甲烷(cf 2 Clh),二氟甲烷(cf 2 H 2),溴二氟甲烷(cf 2 Brh)和二溴氟甲烷(cfbr 2H)可能是氯氟烃(cfc)的替代品.羰基化合物与dmf中原位生成的三苯基phosph的wittig反应形成末端氟代烯烃.但是,在不存在羰基部分的情况下,这些烷基化物会分解.在没有羰基部分的情况下,在dmf中氟亚甲基三苯基phosph的高反应活性已被首次用于设计氢氟烃的合成.
Doi:10.1016/s0022-1139(02)00104-5

专利信息

专利号:US-9126995-B2
优先权日:2011-11-08
标题:Method for catalytic asymmetric synthesis of optically active isoxazoline compound and optically active isoxazoline compound
发明人：TOYAMA KEN-ICHI; MORIYAMA YUJI; MATOBA KAZUTAKA; YAOSAKA MANABU; IKEDA EITATSU
权利人:NISSAN CHEMICAL IND LTD
摘要:There is provided a method for catalytic asymmetric synthesis of optically active isoxazoline compound and an optically active isoxazoline compound. A method for catalytic asymmetric synthesis of optically active isoxazoline compound of a formula (6) including reacting an α,β-unsaturated carbonyl compound of a formula (1) and a hydroxylamine in a solvent in the presence of a base by adding a chiral phase transfer catalyst. An optically active isoxazoline compound of a formula (13) that can be synthesized by the method.

专利号:US-4756739-A
优先权日:1985-12-21
标题 :Pyridine derivatives and the N-oxides thereof, and the use thereof as intermediates for the synthesis of plant protecting agents
发明人：FUSS ANDREAS; KOCH VOLKER
权利人:HOECHST AG
摘要:The compounds of the formula I (I) in which A denotes N or N->O, Z denotes O or NH, R denotes H, (halo)alkyl, (halo)alkenyl, (halo)alkynyl or alkoxycarbonyl, R1 denotes hydrogen, halogen, amino, -NHOH, hydroxyl, (substituted) phenylazo or a radical of the formulae Y=C=N-, Y1Y2C=N-, Y3NH- or K denotes 0 or 1, and m and n, independently of one another, denote a number from 1 to 4, with the proviso that, when Z-R denotes OH or NH2, (R1)n denotes at least one radical of the formula or represents two radicals, in the 5 or 6 position of the heterocyclic ring, which, in the 5 position, denote halogen and, in the 6 position, denote a radical of the group comprising halogen, amino, hydroxyl or phenylazo, which may be substituted as specified above, are valuable intermediates in the synthesis of plant protection agents.

专利号:WO-9925385-A1
优先权日:1997-11-17
标 题:A method of increasing nucleic acid synthesis with ultrasound
发明人：UNGER EVAN C; MCCREERY THOMAS; SADEWASSER DAVID
权利人:IMARX PHARMACEUTICAL CORP
摘要:The present invention is directed to a method of increasing nucleic acid synthesis in a cell comprising administering to the cell a therapeutically effective amount of ultrasound for a therapeutically effective time such that said administration of said ultrasound results in said increased nucleic acid synthesis. The nucleic acid sequence may comprise an endogenous sequence or an exogenous sequence.

专利号:US-2014350261-A1
优先权日:2011-11-08
标 题 :Method for catalytic asymmetric synthesis of optically active isoxazoline compound, and optically active isoxazoline compound

专利号:CN-113493386-A
优先权日:2020-04-08
标 题:A kind of new process of high selectivity asymmetric synthesis of 2-fluorocyclopropylamine

专利号:US-7199105-B2
优先权日:2002-08-15
标 题:Lincomycin derivatives possessing antibacterial activity
发明人：LEWIS JASON G; PATEL DINESH V; ANANDAN SAMPATH KUMAR; GORDEEV MIKHAIL F
权利人:VICURON PHARM INC
摘要:Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against bacteria, including gram positive organisms, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.