CAS: 1516-17-2; Hexa-2,4-Dien-1-Yl Acetate

相似化合物

17102-64-6 2396-84-1 2396-84-1

上下游产品

(2Z,4E)-己二烯酸甲酯 (2Z,4E)-Hexadienoic Acid Methyl Ester 6932-46-3

(2S,3S,E)-Methyl 2-Hydroxy-3-(Trimethylsilyl)Hex-4-Enoate置于lithium Aluminium Tetrahydride,三氟化硼乙醚体系中,用 二氯甲烷 用作溶剂,化学反应生成反,反-2,4-己二烯醛醋酸酯
参考文献:(E)-1-Alkyl-3-Trimethylsilyl-2-Propenyl Glycolates 的 Ester Enolate Claisen 重排和 Peterson 反应立体选择性合成 (2E,4E)-和 (2Z,4E)-2,4-链烷二烯酸酯
标题:(E)-1-Alkyl-3-Trimethylsilyl-2-Propenyl Glycolates 的 Ester Enolate Claisen 重排和 Peterson 反应立体选择性合成 (2E,4E)-和 (2Z,4E)-2,4-链烷二烯酸酯
摘要:(E)-1-烷基-3-三甲基甲硅烷基-2-丙烯基乙醇酸酯的酯烯醇克莱森重排得到具有高非对映选择性的 (E)-Erythro-2-Hydroxy-3-Trimethylsilyl-4-Alkenoates,其被立体选择性地转化为 (通过 Peterson 反应反应生成2E,4E)-和 (2Z,4E)-2,4-链二烯酸酯.
Doi:10.1246/cl.1986.1553

专利信息

专利号:US-4912253-A
优先权日:1988-06-06
标题 :Method for the preparation of an unsaturated alcohol or ester thereof
发明人：FUKUMOTO TAKEHIKO; YAMAMOTO AKIRA
权利人:SHINETSU CHEMICAL CO
摘要:An efficient method is proposed for the synthesis of an unsaturated alcohol of the general formula R--CHâ•?CH(CH 2 ) n+1 OH, in which R is a hydrogen atom or a monovalent hydrocarbon group having 1 to 10 carbon atoms and the subscript n is an integer in the range from 3 to 10, in which an acetate of the formula R--CHâ•?CHCH 2 OCOCH 3 is subjected to a coupling reaction with a Grignard reagent of the formula X 1 Mg(CH 2 ) n OMgX 2 , in which X 1 and X 2 are each a halogen atom, and then the reaction product is hydrolyzed. When the reaction product of the coupling reaction is reacted with acetic anhydride instead of hydrolysis, the corresponding acetate can readily be obtained. These unsaturated alcohols and acetates form a class of important biologically active compounds or intermediates thereof including sex pheromone compounds of insects.

专利号:US-8258362-B2
优先权日:2009-05-04
标 题:Method for the production of α, ω-olefins by using the copper catalyzed coupling reaction of a Grignard reagent with an allylic substrate
发明人：NACHARAJU KRISHNAMURTHY; TAYLOR PAUL D; COONEY MARK J; CRABTREE LARRY A
权利人:NACHARAJU KRISHNAMURTHY; TAYLOR PAUL D; COONEY MARK J; CRABTREE LARRY A; ISP INVESTMENTS INC
摘要:A process for the synthesis of linear α,ω-diolefins from an allylic substrate comprises the steps of a) forming the bis-Grignard reagent XMgCH2(CH2)nCH2MgX from an α,ω-acyclic dihalide with X being a halogen; b) preparing a solution comprising an allylic substrate and a copper catalyst; c) catalyzing a coupling reaction by adding to the solution of step (b) the bis-Grignard reagent of step (a); and d) isolating and purifying the α,ω-olefin coupling reaction product.

专利号:US-12312314-B2
优先权日:2018-05-16
标题:Methods and compositions for terpenoid tricycloalkane synthesis
发明人：GRENNING ALEXANDER JAMES; SCOTT SARAH
权利人:UNIV FLORIDA
摘要:In one aspect, the disclosure relates to methods for preparation of intermediates useful for the preparation of terpenoid cores. In a further aspect, the disclosed methods pertain to the preparation of compounds comprising a terpenoid core or scaffold, such as 6/7/5 tricycloalkanes. The disclosed methods utilize abundant starting materials and simple reaction sequences that can be used to tunably and scalably assemble common terpenoid cores. In various aspects, the present disclosure pertains to compounds prepared using the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

专利号:US-5708168-A
优先权日:1994-11-16
标 题 :Azepine compounds
发明人：KEANA JOHN F W; GUZIKOWSKI ANTHONY P; NOGALES DANIEL F; CAI SUI XIONG
权利人:OREGON STATE; ACEA PHARM INC
摘要:Disclosed are methods of preparing azepines by a multistep synthesis including a Diels-Alder reaction. Also disclosed are methods of treating or preventing neuronal loss associated with stroke, ischemia, CNS trauma, hypoglycemia and surgery, as well as treating neurodegenerative diseases including Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease and Down's syndrome, treating or preventing the adverse consequences of the hyperactivity of the excitatory amino acids, as well as treating anxiety, chronic pain, convulsions, inducing anesthesia and treating or preventing opiate tolerance are disclosed by administering to an animal in need of such treatment an azepine which has high binding to the NMDA glycine site.

专利号:CN-103360248-A
优先权日:2013-07-17
标题:Synthesis method of codling moth sex pheromone intermediate (2E,4E)-2,4-hexadienyl acetate