CAS: 12772-35-9; Butirosin

专利信息

专利号:EP-0542969-B1
优先权日:1991-06-04
标 题:Biodegradable particulate vector and method of synthesis
发明人：SAMAIN DANIEL; DE MIGUEL IGNACIO; MENIALI JAOUAD; IOUALALEN KARIM; DING LI; CERVILLA MONIQUE; RIEUMAJOU VALERIE; DELRIEU PASCAL; IMBERTIE LAURENT
权利人:BIOVECTOR THERAPEUTICS SA
摘要:A biodegradable particulate vector is disclosed and is characterized in that it comprises: a nucleus consisting of a cross-linked polysaccharide or oligosaccharide matrix to which ionic ligands are attached; a first semi-permeable lipid layer linked to the nucleus by covalent bonds; a second layer of amphiphilic compounds linked to the first lipid layer by hydrophobic interactions. A method for synthesis of said vector is also disclosed.

专利号:US-2004053274-A1
优先权日:2002-09-04
标 题 :Gene cluster of vicenistatin biosynthesis, a vicenisamine glycosyltransferase polypeptide, and a gene encoding the polypeptide
发明人：KAKINUMA KATSUMI
权利人:TOKYO INST TECH
摘要:To achieve enzymatic production of vicenistatin, a valuable compound, this invention provides enzymes involved in biosynthesis of vicenistatin and genes encoding the enzymes. This invention provides base sequence of the vin cluster which encodes enzyme complex responsible for biosynthesis of vicenistatin. This invention further provides a glycosyltransferase (VinC enzyme), which catalyzes production of vicenistatin using dTDP-vicenisamine as a substrate. Moreover, this invention provides a gene (vinC gene) encoding the enzyme. The VinC enzyme is useful for enzymatic synthesis of valuable compound vicenistatin. Furthermore, it is suggested that use of the VinC enzyme will enable development of novel polyketide glycosides.

专利号:US-12123041-B2
优先权日:2018-09-21
标 题:Method for the production of amino sugar-containing products
发明人：MAERTENS JO; BAUWENS DAVID; VAN BELLEGEM WOUTER; COUSSEMENT PIETER; DUCHI DRIES; DE MEY MARJAN
权利人:UNIV GENT
摘要:A method or producing amino sugar (containing) products using metabolically engineered microorganisms is disclosed, wherein the conversion of UDP-N-acetylglucosamine to cell envelope precursors and molecules is reduced by altering the activity of enzymes involved in the synthesis of cell envelope precursors and molecules.

专利号:US-2005287169-A1
优先权日:2003-06-17
标 题 :Methods of use of genes of pyridoxal 5'-phosphate biosynthesis in Bacillus subtilis: avirulent strains for vaccines, and methods for identification of antibacterial agents
发明人：BELITSKY BORIS R
权利人:BELITSKY BORIS R
摘要:Methods and compositions comprising a pathogenic bacterial strain having a non-reverting mutation in a pdx gene encoding an enzyme involved in pyridoxal-5′-phosphate synthesis are provided, for use in vaccines, and methods for identification of inhibitors of the enzyme for use as an antibacterial agent are provided.

专利号:US-8148321-B2
优先权日:2006-03-22
标 题 :Bioconjugates as therapeutic agent and synthesis thereof
发明人：ROY RAJENDRA PRASAD; SAMANTARAY SHARMISHTHA
权利人:ROY RAJENDRA PRASAD; SAMANTARAY SHARMISHTHA; NAT INST IMMUNOLOGY
摘要:The present disclosure relates to a novel enzymatic approach according to the invention using an unprecedented sortase-catalyzed transpeptidation reaction between a substrate comprising LPXTG (SEQ ID NO: 11) peptide motif and biomolecules such as aminosugars, hydroxyamino acids, hydroxyamino acid esters, aminolipids, polyamines; nucleic acids or derivatives thereof; or any molecule having such moieties; or any compound having such moieties to obtain a bioconjugates useful for target delivery of a compound. The present disclosure provides bioconjugates obtained by the novel sortase catalysed transpeptidedation reaction.

专利号:DE-102004017141-A1
优先权日:2004-04-01
标 题:New genes from biosynthesis Gene clusters for the synthesis of aminoglycoside antibiotics and thus produced new aminoglycoside antibiotics