CAS: 7469-77-4; 2-Methyl-1-Naphthol

该化合物是一种氯化萘衍生物,在1位有氢氧基组,在2位有甲基组,该化合物是有机合成,特别是染料,药品和农用化学物生产中的多用途中间体,其结构特征可选择性地发挥作用,使其对建设复杂的芳香系统具有价值;该甲基组可增强消毒和电子特性,影响结对反应和替代反应的回弹性. 2-甲基乙基-1-甲硫醇还用于研究由于其荧光特性而导致的光物理行为.高纯度能能确保合成应用的一贯性能.由于对光和空气的潜在敏感性,建议适当处理.

结构式图片

相似化合物

17324-04-8 481-85-6 1076-26-2

欧盟法规

欧盟化妆品法规附录三-限用物质清单ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号604-44-4 4-氯-1-萘酚 | CAS号2586-62-1 1-溴-2-甲基萘 | CAS号13203-73-1 2-METHYLENE-1-O... | CAS号67-56-1 甲醇 | CAS号201230-82-2 carbon monoxide | CAS号24892-64-6 1-but-3-enyl-2-... | CAS号849799-68-4 1-ethynyl-2-(pr... | CAS号5697-02-9 乙酸2-甲基-1-萘基酯 | CAS号110871-49-3 2-methylnaphtha... | CAS号91-57-6 2-甲基萘 | CAS号58-27-5 维生素K3 | CAS号483-55-6 2-羟基-3-甲基-1,4-二... | CAS号76274-21-0 2-methyl-1-oxo-... | CAS号15448-59-6 2-METHYL-2,3-EP... | CAS号1113019-39-8 1,2-dihydro-2-t... | CAS号110327-29-2 4-acetoxy-2-met... | CAS号158749-38-3 1-(4-hydroxy-3-... | CAS号5697-02-9 乙酸2-甲基-1-萘基酯 | CAS号1590-08-5 2-甲基-3,4-二氢-2H-1-萘酮

合成工艺路线路线简述

    📜2-甲基萘置于lead(Iv) Acetate,Sodium Hydroxide体系中,用 乙醇,氯仿 作为反应溶剂,化学反应 20.0H,反应生成 2-甲基-1-萘酚
    参考文献:Greenland,Harry; Pinhey,John T.; Sternhell,Sever,Australian Journal Of Chemistry,1987,Vol. 40,# 2,P. 325-331
    标题:Greenland,Harry; Pinhey,John T.; Sternhell,Sever,Australian Journal Of Chemistry,1987,Vol. 40,# 2,P. 325-331

    海关参考信息

    专利信息


    专利号:US-9409879-B2
    优先权日:2011-03-29
    标 题 :Total synthesis of redox-active 1.4-naphthoquinones and their metabolites and their therapeutic use as antimalarial and schistomicidal agents
    发明人:DAVIOUD-CHARVET ELISABETH; LANFRANCHI DON ANTOINE; JOHANN LAURE; WILLIAMS DAVID LEE; CESAR RODO ELENA
    权利人:DAVIOUD-CHARVET ELISABETH; LANFRANCHI DON ANTOINE; JOHANN LAURE; WILLIAMS DAVID LEE; CESAR RODO ELENA; CENTRE NAT RECH SCIENT
    摘要:Naphthoquinones, azanaphthoquinones and benxanthones, their process of synthesis and methods of their use as antimalarial or antischistosomal agents.

    专利号:US-2004110228-A1
    优先权日:2002-04-01
    标 题:Combinatorial organic synthesis of unique biologically active compounds
    发明人:MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
    摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

    专利号:US-9725392-B2
    优先权日:2015-08-27
    标 题:Efficient scalable syntheses of abscisic acid, 8′-acetylene abscisic acid and 8′-cyclopropyl abscisic acid
    发明人:JHEENGUT Vishal; NELSON KEN M; ABRAMS SUZANNE R
    权利人:NAT RES COUNCIL CANADA
    摘要:Methods are provided for synthesis of abscisic acid and 8′ analogues thereof (including an enantiopure 8′-acetylene analogue) including methods wherein the previously reported first step of oxidation of 2,6-dimethylphenol (VI) to 2,6-dimethylbenzoquinone, mono ketal (VII) is replaced by a novel two step process comprising (i) oxidation of 2,6-dimethylphenol (VI) using potassium peroxymonosulfate with a catalytic amount of iodobenzene to produce 2,6-dimethylbenzoquinone (XVI) and (ii) ketalization of 2,6-dimethylbenzoquinone (XVI) using ethylene glycol, trimethylorthoformate with a catalytic amount of p-toluenesulfonic acid to produce 2,6-dimethylbenzoquinone, mono ketal (VII).

    专利号:US-9051656-B2
    优先权日:2009-07-23
    标题 :Electrochemical synthesis of aryl-alkyl surfacant precursor
    发明人:BHAVARAJU SAI; KARANJIKAR MUKUND; CHITTA PALLAVI
    权利人:BHAVARAJU SAI; KARANJIKAR MUKUND; CHITTA PALLAVI; CERAMATEC INC
    摘要:An aryl-alkyl (R—Ar) hydrocarbon is prepared by an electrosynthesis process in an electrolytic cell having an alkali ion conductive membrane positioned between an anolyte compartment configured with an anode and a catholyte compartment configured with a cathode. An anolyte solution containing an alkali metal salt of an alkyl carboxylic acid and an aryl compound is introduced into the anolyte compartment. The aryl compound may include an alkali metal salt of an aryl carboxylic acid, an arene (aromatic) hydrocarbon, or an aryl alkali metal adduct (Ar − M + ). The anolyte solution undergoes electrolytic decarboxylation to form an alkyl radical. The alkyl radical reacts with the aryl compound to produce the aryl-alkyl hydrocarbon.

    专利号:US-5670698-A
    优先权日:1996-08-19
    标 题:Synthesis of 1-acetoxy-2-methylnaphthalene
    发明人:LIM MU-ILL; PAN YUH-GUO; STASAITIS LINAS; ANDERSON JAMES
    权利人:BRISTOL MYERS SQUIBB CO
    摘要:A one pot process is provided in which a Mannich base of the formula 5 is reacted with acetic anhydride to produce a diacetate derivative. Without any intermediate isolation, the derivative is hydrogenated to produce a reaction mixture containing 1-acetoxy-2-methylnaphthalene which is readily precipitated from the reaction mixture by addition of water. ##STR1##

    专利号:RU-2196764-C2
    优先权日:2001-03-26
    标 题:Method of synthesis of substituted quinones, catalyst for its realization and method of catalyst synthesis

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Ruthenium-Catalyzed Aromatization Of Enediynes Via Highly Regioselective Nucleophilic Additions On A π-Alkyne Functionality. A Useful Method For The Synthesis Of Functionalized Benzene Derivatives
    作者:Arjan Odedra,Chang-Jung Wu,Taduri Bhanu Pratap,Chun-Wei Huang,Ying-Fen Ran,Rai-Shung Liu |发布日期:2005.3.1
    摘要:Tpru(Pph3)(Ch3Cn)2 Pf6 (10 Mol %) Catalyst Effected The Nucleophilic Addition Of Water, Alcohols, Aniline, Acetylacetone, Pyrroles, And Dimethyl Malonate To Unfunctionalized Enediynes Under Suitable Conditions (100 Degrees C, 12-24 H) And Gave Functionalized Benzene Products In Good Yields. In This Novel Cyclization, Nucleophiles Very Regioselectively Attack The Internal C1' Alkyne Carbon Of Enediynes

    合成参考文献


    摘要:Hitomi, Y.; Arakawa, K., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 2, 297.
    摘要:Porco, J. A., Jr.; Boyce, J., Science of Synthesis: Applications of Domino Transformations in Organic Synthesis, (2015) 2, 240.
    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    摘要:Cunha, J. C.; Dedeiras, B.; Negrão, A. C. R.; Marques, M. M. B., Science of Synthesis: Hypervalent Halogens in Organic Synthesis, (2025) .
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