CAS: 72601-82-2; 4-Methyl-7-(((2R,3S,4R,5S,6S)-3,4,5-Trihydroxy-6-Methyltetrahydro-2H-Pyran-2-yl)Oxy)-2H-Chromen-2-One

该化合物是氟氯素胶质的胶质.该化合物的特点是以苯甲醚结构为特征的氟拉夫酮骨干,在7个位置上以星际闪电基取代,该物质由6-dexy-L-galactopyranosyl yl组组成,这表明它有一个糖成分,它能够影响其溶性,生物活动以及与其他分子的相互作用.4个位置的甲基组群有助于其结构多样性,并可能影响其药理特性.包括这一化合物在内的氟拉沃诺类体因其抗氧化特性和潜在健康惠益而闻名,包括抗炎和抗微生物活动.该分子中功能组的具体安排也会影响其再活动性和稳定性.总体而言,这一化合物体现了植物来源产生的天然产品的复杂性和多样性,往往有助于其治疗潜力.

英文名称4-Methyl-7-(((2R,3S,4R,5S,6S)-3,4,5-Trihydroxy-6-Methyltetrahydro-2H-Pyran-2-yl)Oxy)-2H-Chromen-2-One
中文名称4-甲基香豆素基-Β-L-吡喃岩藻糖苷
IUPAC名称4-methyl-7-(((2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one
其它别名4-Methyl-7-(((2R,3S,4R,5S,6S)-3,4,5-Trihydroxy-6-Methyltetrahydro-2H-Pyran-2-yl)Oxy)-2H-Chromen-2-One; 4-Methyl-7-{[(2R,3S,4R,5S,6S)-3,4,5-Trihydroxy-6-Methyloxan-2-Yl]Oxy}-2H-Chromen-2-One; 4-Methylumbelliferyl Beta-L-Fucopyranoside
CAS编号72601-82-2
MFCD编号:MFCD00067660
EINECS号:276-730-0
分子式:C16H18O7分子量:322.31
产品CID: 1711324
产品分类生物化工 → 糖类化合物 → 单糖

相似结构搜索
InChIKey: CQKHENXHLAUMBH-NXPHAWEXSA-N
InChI=1S/C16H18O7/c1-7-5-12(17)23-11-6-9(3-4-10(7)11)22-16-15(20)14(19)13(18)8(2)21-16/h3-6,8,13-16,18-20H,1-2H3/t8-,13+,14+,15-,16+/m0/s1
计算化学: 氢键受体数7.0氢键供体数3.0可旋转键数2.0

MSDS等安全信息

UN编号NONH for all modes of transport
WGK Germany3

上下游产品

2,3,4-tri-O-acetyl-α-L-fucopyranosyl bromide 7-hydroxy-4-methyl-chromen-2-one 1,2,3,4-tetra-O-acetyl-L-rhamnopyranose

合成工艺路线路线简述

📜2,3,4-三-O-乙酰基-6-脱氧-Alpha-L-溴代半乳糖置于甲醇,Sodium Hydroxide,Sodium Methylate,四丁基硫酸氢铵体系中,用二氯甲烷作为反应溶剂,化学反应 4.0H,反应生成 4-甲基香豆素基-β-L-吡喃岩藻糖苷
参考文献:Profiling Of Glycosidase Activities Using Coumarin-Conjugated Glycoside Cocktails
标题:Profiling Of Glycosidase Activities Using Coumarin-Conjugated Glycoside Cocktails
摘要:Glycosidases Are A Large Subgroup Of Carbohydrate-Processing Enzymes That Hydrolytically Cleave The Glycosidic Bond. Glycans Formed By The Action Of Glycosidases Are Involved In Various Biological Processes. Genetic Abnormalities In Glycosidases Are Associated With Inherited Diseases. Thus,Characterization Of The Catalytic Activities Of Glycosidases Is Of Great Importance. Herein,We Describe A Simple And Rapid Approach For Determining Glycosidase Activity Profiles Using Coumarin-Conjugated Glycoside Cocktails.
DOI:10.1021/ol062889F