CAS: 54231-33-3; 3-Bromo-2-Nitropyridine

该化合物是一种有机化合物,其特点是,青春和硝基功能组同时附着于一个环上,其分子结构由六人组成的芳香环组成,内含五个碳原子和一个氮原子,三处有一个溴原子,二处有一个硝基子组.该化合物一般是黄色至褐色的固体,由于反应活跃,并且有能力参与各种化学反应,例如核肺病替代和混合反应,因此在制药和农用化学化学中的潜在应用是众所周知的.溴原子的存在增强了其电子哲学特性,而硝基可用作进一步功能化的多功能处理器.3-Bromo-2-硝基罗丙酮在有机溶剂中溶解,并可能具有中度毒性,在处理过程中需要适当的安全防范.其独特的功能组组合使其成为合成有机化学中有价值的中间体.

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13534-99-1 610261-34-2 39856-50-3

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MSDS等安全信息

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ECHA物质C&L通报

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CAS号54231-38-8 3-溴-2-吗啉吡啶 | CAS号36178-05-9 3-溴-2-氟吡啶 | CAS号13534-99-1 2-氨基-3-溴吡啶 | CAS号77200-37-4 [3,3'-Bipyridin... | CAS号54231-44-6 4-(2-氯-3-吡啶)吗啉 | CAS号54231-45-7 4-(2-bromopyrid...

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    专利号:US-8735586-B2
    优先权日:2007-06-26
    标 题 :Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles
    发明人：ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR
    权利人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR; SANOFI SA
    摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, n nwherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct copper catalyzed regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

    专利号:EP-2173747-B1
    优先权日:2007-06-26
    标 题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles
    发明人：ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARE MARC; R KYEN OMAR; URMANN MATHIAS; HALLAND NIS
    权利人:SANOFI SA
    摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R1; R2; R3; R4; J1; J2; J3; J4 and G have the meanings indicated in the claims. The present invention provides a direct metal, e.g. palladium or copper, catalyzed, regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

    专利号:US-9919064-B2
    优先权日:2012-08-10
    标 题 :Compositions, methods, and systems for the synthesis and use of imaging agents
    发明人：CESATI RICHARD R; RADEKE HEIKE S; PANDEY SURESH K; PUROHIT AJAY; ROBINSON SIMON P
    权利人:LANTHEUS MEDICAL IMAGING INC
    摘要:The present invention provides compounds with imaging moieties for imaging a subject. The present invention also relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, a composition or plurality of imaging agents is enriched in 18 F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.

    专利号:US-2010261909-A1
    优先权日:2007-06-26
    标题 :Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles

    专利号:WO-2009000413-A1
    优先权日:2007-06-26
    标题:A regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles

    专利号:CA-2693142-A1
    优先权日:2007-06-26
    标题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles

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    摘要:Wang, X.; Hu, J., Science of Synthesis: Modern Strategies in Organofluorine Chemistry, (2025) 2.
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