CAS: 52190-35-9; 2-(Methylthio)Cyclohexan-1-One

相似化合物

134108-72-8 22842-45-1 874-23-7

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CAS号6651-36-1 1-环己烯氧基三甲基硅烷 | CAS号5799-67-7 二甲基(甲硫代)锍四氟硼酸盐 | CAS号110-83-8 环己烯 | CAS号110466-28-9 N-(2-(methylthi... | CAS号542-18-7 氯代环己烷 | CAS号5188-07-8 甲硫醇钠 | CAS号624-92-0 二甲基二硫醚 | CAS号108-94-1 环己酮 | CAS号67-68-5 二甲基亚砜 | CAS号5682-83-7 2-苯亚甲基环己酮 | CAS号765-87-7 1,2-环己二酮 | CAS号1121-18-2 2-甲基-2-环己烯-1-酮 | CAS号13694-36-5 2-benzylcyclohe... | CAS号85058-04-4 2-propylsulfony... | CAS号89729-99-7 2-hexylsulfonyl... | CAS号89730-00-7 2-(2-phenylethy... | CAS号89730-08-5 2-nonylsulfonyl... | CAS号89730-09-6 2-but-3-enylsul... | CAS号99861-33-3 ethyl 3-(6-ox°C...

📜1,1'-联(环己烷)-1'-烯-2-胺置于正丁基锂,草酸,二异丙胺体系中,用 水 作为反应溶剂,化学反应 38.5H,反应生成 2-(甲硫基)环己酮
参考文献:Synthesis Of Enantiomerically Enriched α-Sulfenylated Ketones And Aldehydes
标题:Synthesis Of Enantiomerically Enriched α-Sulfenylated Ketones And Aldehydes
摘要:通过含有α-氢的醛和酮的亚胺与二硫化物的反应,利用金属烯胺制备α-硫代羰基化合物.以(R)-α-苯乙胺作为手性辅助剂,观测到13-51%的对映体过量.
DOI:10.1055/s-1987-27870

专利信息

专利号:US-3901899-A
优先权日:1973-04-27
标题 :Synthesis of indoles from anilines and intermediates therein
发明人：GASSMAN PAUL G
权利人:UNIV OHIO STATE RES FOUND
摘要:Preparing indoles and intermediates therefor by reacting an Nhaloaniline with a Beta -carbonylic hydrocarbon sulfide to form an azasulfonium halide, reacting the azasulfonium halide with a strong base to form a thio-ether indole derivative, and then reducing the thio-ether indole, e.g. with Raney nickel, to form the indole compound. When an acetal or ketal of the Beta carbonyl hydrocarbon sulfide is used, the azasulfonium salt is treated with a base, and then with an acid to form the thio-ether indole derivative. When an Alpha -ethyl- Beta -carbonylic hydrocarbon sulfide is used, the resulting azosulfonium salt reacts with strong base to form a thio-ether indolenine derivative, which on reduction with Raney nickel or complex metal hydrides yields 3-substituted indoles. The aniline may be an aminopyridine to form an aza-indole compound in the process. The azasulfonium salts and thio-ether indole or thio-ether indolenine derivatives can be isolated and recovered from their respective reaction mixtures. The thio-ether-indole and thio-ether indolenine derivatives are useful as intermediates to make the indoles without the thio-ether group. The indoles are known compounds having a wide variety of uses, e.g., in making perfumes, dyes, amino acids, pharmaceuticals, agricultural chemicals and the like.

专利号:US-3992392-A
优先权日:1973-04-27
标题:Synthesis of indoles from anilines and intermediates therein
发明人：GASSMAN PAUL G
权利人:UNIV OHIO STATE RES FOUND
摘要:Preparing indoles and intermediates therefor by reacting an N-haloaniline with a β-carbonylic hydrocarbon sulfide to form an azasulfonium halide, reacting the azasulfonium halide with a strong base to form a thio-ether indole derivative, and then reducing the thio-ether indole, e.g. with Raney nickel, to form the indole compound. When an acetal or ketal of the β-carbonyl hydrocarbon sulfide is used, the azasulfonium salt is treated with a base, and then with an acid to form the thio-ether indole derivative. When an α-ethyl-β -carbonylic hydrocarbon sulfide is used, the resulting azosulfonium salt reacts with strong base to form a thio-ether indolenine derivative, which on reduction with Raney nickel or complex metal hydrides yields 3-substituted indoles. The aniline may be an aminopyridine to form an aza-indole compound in the process. The azasulfonium salts and thio-ether indole or thio-ether indolenine derivatives can be isolated and recovered from their respective reaction mixtures. The thio-ether-indole and thio-ether indolenine derivatives are useful as intermediates to make the indoles without the thio-ether group. The indoles are known compounds having a wide variety of uses, e.g., in making perfumes, dyes, amino acids, pharmaceuticals, agricultural chemicals and the like.

专利号:CA-1043337-A
优先权日:1973-04-27
标题 :Synthesis of indoles from anilines and intermediates therein