CAS: 41451-87-0; (2S,3R,5R,9R,10R,11R,13R,14S,17S)-2,3,11,14-Tetrahydroxy-10,13-Dimethyl-17-((2R,3R)-2,3,6-Trihydroxy-6-Methylheptan-2-yl)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-Tetradecahydro-6H-Cyclopenta[a]Phenanthren-6-One

该化合物是自然产生的雌性激素,昆虫和某些植物,特别是Ajuga turkestanica物种中发现的一种激素,其特点是类固醇结构,包括环戊烷环和多种氢氧基,有助于其生物活动;突厥酯有其潜在的代谢效应,经常作为辅助剂销售,以提高肌肉生长,提高运动性能和支持恢复;据信它会影响蛋白质合成,并可能具有适应性特性,帮助身体应对压力;此外,酯表现出抗氧化剂和抗炎效应,使其在各种健康和健康应用中引起兴趣;其溶解性主要在有机溶剂中,在正常条件下相对稳定;然而,与任何补充一样,必须进一步研究,以充分了解其对人类的功效和安全.

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    专利信息


    专利号:US-2014274978-A1
    优先权日:2013-03-15
    标题 :Phytosterol spirostane and spirostene derivatives having a wide variety of utilities in humans and other animals
    发明人:FASCIOLA ANDRE ARMEL
    权利人:FASCIOLA ANDRE ARMEL
    摘要:The present invention utilizes phytosterol, phytoecdysteroid, sapogenin, triterpene, terpene, spirostane, spirostene and androstene derivative compounds to provide a wide variety of utilities to humans and other animals. The compounds and methods provide numerous and wide-ranging benefits including biochemical and constructive metabolic benefits including increases in protein synthesis and synthesis efficiency, ergogenic, adaptogenic, cosmetic and medicinal skin agents and veterinary utilities. The compounds provide agents that increase physical endurance and work output, act as a general tonic for increasing health and vigor, increase sleep time and sleep efficiency and act as rejuvenating agents to reverse the effects of fatigue and stress. Novel utilities for pet, farm, zoo and companion animals are also provided.

    专利号:US-9700589-B2
    优先权日:2015-02-03
    标题:Compositions and methods for improved muscle metabolism
    发明人:BILY ANTOINE CHARLES; MEYER MARJOLAINE; CHEVALIER KARL; Laurençon Lise; FEUILLERE NICOLAS; ROLLER MARC; BIRTIC SIMONA
    权利人:NATUREX SA
    摘要:A composition for improving muscle metabolism in a subject and methods for manufacturing and using same. Embodiments include compositions having an extract of Rhaponticum and an extract of Rhodiola . An extract of Rhaponticum may include amounts of ecdysterones including 20-hydroxyecdysone. An extract of Rhodiola my include salidrosides and rosavins, including rosavin. Suitable ingestion dosages of the composition may be operable to increase protein synthesis and reduce protein proteolysis in a subject.

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    主要参考文献


    1: Guibout L, Mamadalieva N, Balducci C, Girault JP, Lafont R. The minor ecdysteroids from Ajuga turkestanica. Phytochem Anal. 2015 Sep- Oct;26(5):293-300. doi: 10.1002/pca.2563. Epub 2015 May 8.
    3:6. doi: 10.1093/jis/3.1.6. Epub 2003 Feb 24.
    3: Syrov VN, Kurmukov AG, Sakhibov AD. Vliianie turkesterona i nerobola na aktivnost' beloksinteziruiushcheĭ sistemy pecheni mysheĭ [Effect of turkesterone and nerobol on the activity of the protein synthesizing system of mouse liver]. Vopr Med Khim. 1978 Jul-Aug;24(4):456-60. Russian. 32(5):24-8. Russian. 22(3):107-12. Russian. 75(5):28-31. Russian. 72(3):215-20. doi: 10.1016/s0367-326x(00)00304-x. 77(7):35-8. Russian. 16(8):2581-8. doi: 10.1007/BF01017480. 60(3):41-4. Russian. 65(11):1690-2. doi: 10.1021/np020199o. 26(6):442-6. Chinese. 73(5):502-14. doi: 10.1016/j.steroids.2007.12.021. Epub 2007 Dec 28. Erratum in: Steroids. 2009 Nov;74(12):1003-4.

    合成参考文献


    参考文献:10.1080/10286020290019631
    摘要:Tan C, Wang J, Zhang H, Li X. A new phytosterone from Cyanotis arachnoidea. Journal of Asian Natural Products Research. 2002 Jan;4(1):7–11. doi: 10.1080/10286020290019631.
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