CAS: 348-59-4; 2,5-Dichlorofluorobenzene

上下游产品

CAS号95-82-9 2,5-二氯苯胺 | CAS号13656-50-3 2,5-dichloro-4-... | CAS号351-28-0 3-氟乙酰苯胺 | CAS号351-31-5 acetic acid-(4-... | CAS号106-46-7 1,4-二氯苯 | CAS号367-22-6 4-氯-3-氟苯胺 | CAS号36556-50-0 2,3-二氯氟苯 | CAS号583-78-8 2,5-二氯苯酚 | CAS号1984-58-3 2,5-二氯苯甲醚

2,5-二氯苯胺置于盐酸,Fluoroboric Acid,Sodium Nitrite体系中,用 水,邻二氯苯 用作溶剂,化学反应 0.03H,以95%的收率获得1,4-二氯-2-氟苯
参考文献:用于balz-Schiemann反应的连续流反应器:制备芳族氟化物的新程序
标题:用于balz-Schiemann反应的连续流反应器:制备芳族氟化物的新程序
摘要:建立了通过两个连续流动反应器通过balz-Schiemann反应制备芳族氟化物的简便高效方法.连续重氮化反应器在约25oc下运行,停留时间为10-20 S,连续氟脱氮反应器以1分钟的停留时间进行高收率.通过提高温度可以大大缩短反应时间,从而充分利用连续流系统的卓越质量和传热能力.
Doi:10.1016/j.Tetlet.2012.12.084

专利信息

专利号:US-7393980-B2
优先权日:2001-05-17
标题:Use of a composition of an ionic nature as a substrate reagent, a composition constituting a fluorination reagent and a method using same
发明人：GARAYT MAXIME; LE BOULAIRE VIRGINIE; GREE DANIELLE; GREE RENE; SCHANEN VINCENT; SPINDLER JEAN-FRANCIS
权利人:RHODIA CHIMIE SA
摘要:The invention relates to a novel method for producing nucleophilic substitutions, particularly of type SNAr and SN2. More specifically, the invention relates to the use as a fluorinating reaction medium of ionic liquid or fused salt comprising at least four carbon atoms. The invention can be used for the synthesis of fluoride derivatives.