CAS: 304-84-7; N,N-Diethyl-4-Hydroxy-3-Methoxybenzamide
- ⚠️《2026年兴奋剂目录》
- 英文名称N,N-Diethyl-4-Hydroxy-3-Methoxybenzamide
- 中文名称益迷兴
- IUPAC名称Benzamide, N,N-diethyl-4-hydroxy-3-methoxy-
- 其它别名Vanillamide,N,N-diethyl- (6CI,7CI,8CI); 3-Methoxy-4-hydroxybenzoic acid diethylamide; Analepticon; Cardiovanil; Corivanil; Diethamivan; Diethylvanillamide; Emivan; Etamivan; Etamivanum; Ethamivan; N,N-Diethyl-4-hydroxy-3-methoxybenzamide; N,N-Diethylvanillamide; Romecor; Sevanil; Simaron; Vandid; Vanillicacid N,N-diethylamide; Vanillic acid diethylamide; Vanillic diethylamide; Ventilone
- CAS编号304-84-7
- MFCD编号:MFCD00026727
- EINECS号:206-157-3
- FDA UNII编号:M44O63YPV9
- 分子式:C12H17NO3分子量:223.27
- 产品CID: 1290198
- 产品分类原料药 → 神经系统用药 → 中枢兴奋药
物理性质
MSDS等安全信息
欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
CAS号121-34-6 香草酸 | CAS号109-89-7 二乙胺合成工艺路线路线简述
📜香草酸,二乙胺置于氯化亚砜,N,N-二甲基甲酰胺体系中,用 二氯甲烷 作为反应溶剂,化学反应生成 香草二乙胺
参考文献:酪烷型二萜吡罗萨尔文的全合成
标题:酪烷型二萜吡罗萨尔文的全合成
摘要:本文基于 Brieskorn 和 Fuchs 描述的结构框架,首次成功全合成了 Pikrosalvin,这是一种从丹参中天然提取的化合物.我们的合成方法以仿生策略为基础,该策略受到通过多烯环化生物合成萜烯的 Stork-Eschenmoser 假说的启发.从市售香草酸和香叶醇开始,我们策略性地组装了pikrosalvin的结构核心,由十氢萘a/b环,芳香族c环和丁内酯d环组成.与保护基团和特定催化条件相关的挑战得到有效解决,从而实现了高产品收率.我们进一步证明了联合酸催化多烯环化方法在复杂天然产物合成中的功效和广泛适用性.这项研究为 Pikrosalvin 未来的生物学和药理学研究奠定了基础.
DOI:10.1002/jccs.202300384
海关参考信息
- 2905110000-甲醇
2907210001-间苯二酚
2912110000-甲醛
2912210000-苯甲醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-7772218-B2
优先权日:2000-02-11
标 题 :Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one
发明人：PETERS RICHARD H; LIU JYANWEI; JOHANSSON JOHN G; RYAN KENNETH J; CHAO WAN-RU; TANABE MASATO
权利人:STANFORD RES INST INT
摘要:Syntheses of steroids such as 3-hydroxy-7α-methyl-21-[2′-methoxy-4′-(diethylaminomethyl)-phenoxy]-19-norpregna-1,3,5(10)triene citrate (“SR 16234â€?) and analogs thereof are provided, wherein 21-hydroxy-19-norpregna-4-en-3-one serves as a starting material or intermediate. The latter compound may be readily prepared from estrone-3-methyl ether. Certain intermediates in these syntheses also have value as therapeutic agents, for example in the treatment of prostate disorders such as prostatic cancer.
专利号:US-2005009801-A1
优先权日:2000-02-11
标 题:Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one
专利号:US-2001039269-A1
优先权日:2000-02-11
标题:Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one
专利号:US-6784170-B2
优先权日:2000-02-11
标 题:Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one
专利号:WO-0158919-A2
优先权日:2000-02-11
标题 :Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one
专利号:WO-0158919-A9
优先权日:2000-02-11
标 题 :Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Yi B, Hu L, Mei W, Zhou K, Wang H, Luo Y, Wei X, Dai H. Antioxidant phenolic compounds of cassava (Manihot esculenta) from Hainan. Molecules. 2011 Dec 7;16(12):10157-67. doi: 10.3390/molecules161210157. Chinese. Chinese.
10: Jovanović UJ, Liebaldt GP. [Clinical, clinical-chemical and cerebral bioelectric testing of a combination of hexobendine, ethamivan and hydroxyethyltheophyllin]. Arzneimittelforschung. 1970 Sep;20(9):1223-30. German.
13: Yenel F. [Use of ethamivan as a respiratory stimulant in the treatment of pulmonary insufficiency]. Turk Tip Cemiy Mecm. 1970;36(9):332-7. Turkish.
合成参考文献
摘要:Psychotropic Drugs and Related Compounds, 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972, -(377), 1972
摘要:Research Progress in Organic-Biological and Medicinal Chemistry., 1(423), 1964
摘要:Acta Biologica et Medica Germanica., 9(67), 1962 []
摘要:Comptes Rendus Hebdomadaires des Seances, Academie des Sciences., 243(609), 1956
摘要:Annales Pharmaceutiques Francaises., 17(41), 1959
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