CAS: 26348-70-9; H-Lys-Ome.2Hcl

该化合物是氨基酸碱的受保护衍生物,广泛用于peptide合成和生化研究.甲基酯组增强溶解性和再活性,促进固相和溶液阶段peptide合成中的有效结合.二氢氯化盐形式确保改善稳定性和处理.该化合物对于将碱性残留引入peptide链,同时最大限度地减少侧面反应特别有用.其高纯度和一贯性能使它成为药物开发,蛋白质组学和酶学研究的可靠选择.建议在无水条件下适当储存以保持其完整性.

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34015-48-0 2389-48-2 27894-50-4

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上下游产品

methanol L-lysine L-Lysine hydr°Chloride 2,2-dimethoxy-propane 22H33N4O6C22H33N4O6 (S)-2-{(2R,3R,Z)-1-[(S)-2-benzamido-6-guanidinohexanoyl]-4-ethylidene-3-methylpyrrolidine-2-carboxamido}-4-methyl-pentanoic acid (S)-2-{(2R,3S,Z)-1-[(S)-2-benzamido-6-guanidinohexanoyl]-4-ethylidene-3-methylpyrrolidine-2-carboxamido}-4-methyl-pentanoic acid

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    专利信息


    专利号:WO-2019076178-A1
    优先权日:2017-10-18
    标 题:Medical degradable polyurethane with adjustable degradation time and adjustable elongation at break
    发明人:ZHANG WENFANG
    权利人:COMSCAFFOLDS NANJING MEDICAL DEVICE CO LTD
    摘要:The invention provides a medical degradable polyurethane with adjustable degradation time and adjustable elongation at break, a preparation method and application thereof, and can adjust the proportion of each component in the polyurethane synthesis process and select different chain extenders. Control the performance of PU in a wide range, such as PU degradation time, elongation at break, strength, lubricity and hydrophilicity, etc., can choose different properties of medical degradable polyurethane according to the needs of regenerative medicine and medical devices implanted in the body. .

    专利号:US-2009240028-A1
    优先权日:2003-08-08
    标 题:Synthesis and Application of New Structural Well Defined Branched Polymers as Conjugating Agents for Peptides

    专利号:US-2006182714-A1
    优先权日:2003-08-08
    标题:Synthesis and application of new structural well defined branched polymers as conjugating agents for peptides

    专利号:CN-108794572-A
    优先权日:2017-04-27
    标 题:A kind of total synthesis method of natural product Lucentamycin A

    专利号:CN-108794572-B
    优先权日:2017-04-27
    标题:Total synthesis method of natural product Lucentamycin A
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    主要参考文献

    [参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
    [参考文献]: Atoosa Maleki, Et Al. Characterization Of The Chemical Degradation Of Hyaluronic Acid During Chemical Gelation In The Presence Of Different Cross-Linker Agents. Carbohydr Res. 2007 Dec 28;342(18):2776-92.
    [参考文献]: Aurora Pinazo, Et Al. Lysine-Bisglycidol Conjugates As Novel Lysine Cationic Surfactants. Langmuir. 2009 Jul 21;25(14):7803-14.
    [参考文献]: Kira A Watkins, Et Al. Ph-Responsive, Lysine-Based Hydrogels For The Oral Delivery Of A Wide Size Range Of Molecules. Int J Pharm. 2015 Jan 30;478(2):496-503.
    [参考文献]: Zhen Ye, Et Al. A Neutral Polydisulfide Containing Gd(Iii) Dota Monoamide As A Redox-Sensitive Biodegradable Macromolecular Mri Contrast Agent. Contrast Media Mol Imaging. 2016 Jan-Feb;11(1):32-40.

    合成参考文献


    参考文献:10.1007/s11172-005-0411-4
    摘要:Finocchiaro P, Failla S, Consiglio G. Phosphorylated macrocycles: structures, complexing properties, and molecular recognition. Russian Chemical Bulletin. 2005 Jun;54(6):1355–72. doi: 10.1007/s11172-005-0411-4.
    参考文献:10.1007/bf01332948
    摘要:Schfißler U, Ledl F. Synthesis of 2-amino-6-(2-formyl-5-hydroxymethyl-1-pyrrolyl-)hexanoic acid. European Food Research and Technology. 1989 Aug;189(2):138–40. doi: 10.1007/bf01332948.
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