CAS: 2017-67-6; 2-(Naphthalen-2-yl)Ethan-1-Amine Hydrochloride

相似化合物

36660-46-5 4735-50-6 2668984-44-7

上下游产品

naphthalen-2-ethanol 2-naphthaleneacetonitrile

📜2-萘乙腈置于盐酸,9-Borabicyclo[3.3.1]Nonane Dimer体系中,用 乙醚 用作溶剂,化学反应 25.0H,反应生成2-(2-萘基)乙胺 盐酸盐
参考文献:硼烷催化丁腈硼氢化的硼-氮双转硼化策略
标题:硼烷催化丁腈硼氢化的硼-氮双转硼化策略
摘要:腈的有机硼烷催化硼氢化提供了n,N-二硼胺,它们作为合成伯胺和仲酰胺的有效合成子.已知的腈硼氢化方法以金属催化为主.报道了使用乙硼烷 [hb-9-Bbn] 2作为催化剂和频哪醇硼烷作为周转试剂对腈进行简单且无金属的硼氢化反应.单体 Hb-9-Bbn 与腈反应生成氢化桥联二硼亚胺中间体;提出了随后的涉及bn / Bh σ键复分解的顺序双硼氢化-转硼化途径.
Doi:10.1021/acs.Joc.2C01655

专利信息

专利号:US-5075339-A
优先权日:1989-07-28
标 题:Benzylketone phospholipase A2 inhibitors
发明人：WILKERSON WENDELL W
权利人:DU PONT MERCK PHARMA
摘要:The invention relates to benzylketone phospholipase A2 inhibitors, pharmaceutical compositions containing them, and methods of treating phospholipase A2-mediated conditions in mammals by administration of a therapeutically effective amount of such a benzylketone phospholipase A2 inhibitor. These compounds are also intermediates in the synthesis of other PLA2 inhibitors.

专利号:US-4948813-A
优先权日:1987-11-30
标题 :Benzylketone phospholipase A2 inhibitors
发明人：WILKERSON WENDELL W
权利人:DU PONT
摘要:The invention relates to benzylketone phospholipase A2 inhibitors, pharmaceutical compositions containing them, and methods of treating phospholipase A2-mediated conditions in mammals by administration of a therapeutically effective amount of such a benzylketone phospholipase A2 inhibitor. These compounds are also intermediates in the synthesis of other PLA2 inhibitors.