CAS: 1676-75-1; (S)-2-(((Benzyloxy)Carbonyl)Amino)-3-(Tert-Butoxy)Propanoic Acid

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65806-90-8 1145-80-8 128107-47-1

上下游产品

CAS号1676-81-9 N-苄氧羰基-L-丝氨酸甲酯 | CAS号1145-80-8 |N|-苄氧羰基-L-丝氨酸 | CAS号58455-98-4 z-ser(tbu)-otbu | CAS号1872-59-9 O-叔丁基-N-苄氧羰基-L-丝氨酸甲酯 | CAS号6169-34-2 N-Benzyloxycarb... | CAS号6169-33-1 N-(benzyloxycar... | CAS号59859-77-7 Z-Ser-OtBu | CAS号289655-98-7 N-[(phenylmetho... | CAS号501-53-1 氯甲酸苄酯 | CAS号19460-97-0 ZL-Ser(tBu)-OSu | CAS号18822-58-7 O-叔丁基-L-丝氨酸 | CAS号1872-59-9 O-叔丁基-N-苄氧羰基-L-丝氨酸甲酯 | CAS号17083-26-0 H-SER(TBU)-甲氧基盐酸盐 | CAS号117106-19-1 ZN-Me-L-Ser(tBu...

N-Benzyloxycarbonyl-β-O-Tert.Butyl-L-Serin-<4-Nitro-Benzylester> 反应生成N-苄氧羰基-O-叔丁基-L-丝氨酸
参考文献:Zitsane,D. R.;Ravinya,I. T.;Tetere,Z. F.;Rijkure,I. A.;Gudrinietse,E+,Izv. An Latvssr. Cep. Xim.,(1990) N,S. 357-359
标题:Zitsane,D. R.;Ravinya,I. T.;Tetere,Z. F.;Rijkure,I. A.;Gudrinietse,E+,Izv. An Latvssr. Cep. Xim.,(1990) N,S. 357-359

专利信息

专利号:US-7435791-B2
优先权日:2001-07-19
标题:Process for rapid solution synthesis of peptides
发明人：EGGEN IVO FRANCI; TEN KORTENAAR PAULUS BERNARDUS; HAASNOOT CORNELIS ALBERT GRUSON
权利人:ORGANON NV
摘要:The present invention relates to a process for rapid solution synthesis of a peptide, the process comprising repetitive cycles of steps (a)-(d):n (a) a coupling step, using an excess of an activated carboxylic component to acylate an amino component, (b) a quenching step in which a scavenger is used to remove residual activated carboxylic functions, wherein the scavenger may also be used for deprotection of the growing peptide, (c) one or more aqueous extractions and optionally, (d) a separate deprotection step, followed by one or more aqueous extractions, characterised in that the process comprises at least one step (b), referred to as step (b′), in which an amine or a thiol comprising a free anion or a latent anion is used as a scavenger of residual activated carboxylic functions. nn During the process of this invention the growing peptide need not be isolated until the final peptide sequence has been obtained. n This highly efficient process is useful for the production of oligo- and polypeptides of high purity.

专利号:US-4504415-A
优先权日:1983-04-04
标题:Synthesis of thymosin α1 and desacetyl thymosin α1
发明人：FELIX ARTHUR M; GILLESSEN DIETER; STUDER ROLF; MEIENHOFER JOHANNES A; TRZECIAK ARNOLD
权利人:HOFFMANN LA ROCHE
摘要:An improved solution phase synthesis of thymosin alpha 1 and desacetyl thymosin alpha 1 with t-Boc side chain protection and proceeding through novel intermediates is disclosed.

专利号:US-4517119-A
优先权日:1983-04-04
标题:Synthesis of thymosin α1
发明人：FELIX ARTHUR M; GILLESSEN DIETER; LERGIER WILLIAM; MEIENHOFER JOHANNES A; TRZECIAK ARNOLD
权利人:HOFFMANN LA ROCHE
摘要:An improved solution phase synthesis of thymosin α 1 and proceeding through novel intermediates is disclosed.

专利号:PL-205559-B1
优先权日:2001-07-19
标 题 :Method of peptide synthesis in solution, method of combinatorial synthesis of a peptide library and method of automated peptide synthesis in solution

专利号:US-10407468-B2
优先权日:2016-03-23
标 题 :Methods for synthesizing α4β7 peptide antagonists
发明人：BHANDARI ASHOK; MANTHATI SURESH KUMAR; MEHROTRA MUKUND M; ANANDAN SAMPATH-KUMAR; PATEL DINESH V
权利人:PROTAGONIST THERAPEUTICS INC
摘要:The present invention provides methods of making α4β7 peptide monomer and dimer antagonists. Methods of the present invention include solid phase and solution phase methods, as well as synthesis via condensation of smaller peptide fragments. Methods of the present invention further include methods directed to the synthesis of peptides comprising one or more penicillamine residues.

专利号:US-5434138-A
优先权日:1990-08-04
标 题:Gonadoliberin antagonists
发明人：KOENIG WOLFGANG; SANDOW JUERGEN; KOLAR CENEK
权利人:HOECHST AG
摘要:Peptides of the formula in which X is alkanoyl, A is optionally substituted D-Nal(2), D-Phe or D-Trp, B is optionally substituted D-Phe, C is D-Pal(3) or optionally substituted D-Phe or D-Trp, and D is Tyr or His, E is D-Ser (R1), F is Leu, Trp or Phe, G is L-Ser(R1), H is Gly-NH2, D-Ala-NH2 or Azagly-NH2 and R1 is a glycosyl radical. These peptides have an inhibitory effect on the formation of the gonadotropins lutropin and follitropin and thus also on the synthesis of testo-sterone and estrogen. A process for the preparation of these peptides is described.