CAS: 15862-72-3; Ethyl Pipecolinate

相似化合物

77034-33-4 22328-78-5 183786-20-1

上下游产品

CAS号2524-52-9 2-吡啶甲酸乙酯 | CAS号64-17-5 乙醇 | CAS号4043-87-2 2-哌啶甲酸 | CAS号98-98-6 2-吡啶甲酸 | CAS号105855-20-7 ethyl 1-(naphth... | CAS号4430-75-5 八氢吡啶并[1,2-a]吡嗪 | CAS号30727-18-5 N-甲基-2-哌啶甲酸乙酯 | CAS号4043-87-2 2-哌啶甲酸 | CAS号180533-19-1 2-Pyridinecarbo... | CAS号18391-75-8 2-phenyl-3-sulf... | CAS号219718-34-0 ethyl 1-chlorop... | CAS号3433-37-2 2-哌啶甲醇 | CAS号15932-71-5 2H-Pyrido[1,2-a... | CAS号126401-22-7 N-Cbz-哌啶-2-羧酸乙酯

2-吡啶甲酸乙酯置于rhodium(III) Oxide,氢气体系中,用 2,2,2-三氟乙醇 用作溶剂,40.0 °C,500.01 Kpa 条件下,以99%的收率获得2-哌啶甲酸乙酯
参考文献:在温和条件下用氧化铑催化剂氢化官能化吡啶
标题:在温和条件下用氧化铑催化剂氢化官能化吡啶
摘要:哌啶是药物和农化化合物合成中使用最广泛的结构单元之一.吡啶的氢化是合成此类化合物的便捷方法,因为它只需要反应物,催化剂和氢源.然而,该反应对于官能化和多取代吡啶的还原仍然很困难.在这里,我们报道了使用稳定的市售铑化合物rh 2 O 3来还原各种未保护的吡啶.该反应条件温和,底物范围广,具有实用价值.
Doi:10.1039/d3Ob01860A

专利信息

专利号:WO-9740052-A1
优先权日:1996-04-22
标题 :Propagylglycine derivatives, preparation and utilisation thereof as synthesis intermediates
发明人：CARDINAUD ISABELLE; CHEKROUN ISAAC; ROSSEY GUY; CREMER GERARD; GOBERVILLE PASCALE; HOORNAERT CHRISTIAN
权利人:SYNTHELABO; CARDINAUD ISABELLE; CHEKROUN ISAAC; ROSSEY GUY; CREMER GERARD; GOBERVILLE PASCALE; HOORNAERT CHRISTIAN
摘要:Compounds of formula (I) wherein R2 is -CH2C=CH or -CH2C=C-Het where Het is a 2-aminopyridyl, 2-aminopyrimidyl, 6-aminopyridazinyl, imidazol-4-yl group, R3 and R4 each represent hydrogen, (C1-C4)alkyl, (C1-C4)alkoxycarbonyl, ArCH2CO2- or ArSO2- where Ar is an aryl group, or a group (a) where R7 is hydrogen or -COR, R being straight or branched (C1-C7) alkyl, -(CH2)nOCH3 or -CH2O(C2H4O)nCH3 (n is 1, 2 or 3) and A is chosen among the phenyl, pyrimidyl, pyridinyl, thienyl, thiazolyl and furyl groups, R6 represents either a straight or branched (C1-C4) alkoxy group, or a benzyloxy group or a group (b) where R12 is a hydrogen atom or a carboxylic or (C1-C4)alkoxycarbonyl group and R13 is a straight or branched (C1-C4)alkyl group. They constitute synthesis intermediates.

专利号:WO-2012136504-A1
优先权日:2011-04-04
标 题:Method for the preparation of process intermediates for the synthesis of argatroban monohydrate

专利号:US-4560752-A
优先权日:1984-03-02
标题:Phosphinates or phosphonates useful for control of weeds
发明人：LEE SHY-FUH
权利人:ZOECON CORP
摘要:Novel 5-(substituted amino)phenoxyalkyl-, phenylthioalkyl-, phenylsulfinylalkyl-, and phenylsulfonylalkylphosphinates and phosphonates, synthesis thereof, intermediates therefor, and the use of said novel compounds for the control of weeds.

专利号:US-2014243333-A1
优先权日:2008-09-26
标题:Synthesis of functionalized octahydro-isoquinolin-1-one-8-carboxylic esters and analogs, and therapeutic methods

专利号:US-2010256142-A1
优先权日:2008-09-26
标 题 :Synthesis of functionalized octahydro-isoquinolin-1-one-8- carboxamides, octahydro-isoquinolin-1-one-8-carboxylic esters and analogs, and therapeutic methods

专利号:US-2008200475-A1
优先权日:2005-03-28
标题:4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors
发明人：ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; TENBRINK RUTH ELIZABETH
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: (I) wherein A 1 , A 2 , A 3 , A 4 , A 5 , A 6 , A 7 , A 8 , X 4 , X 6 , R 2a , R x , R 4 , R 5 , and R 6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.