CAS: 845273-93-0; Carbonic Acid--Prop-2-En-1-Amine--2-(Chloromethyl)Oxirane (1/1/1)

反应生成 碳酸司维拉姆
参考文献: Processes For The Preparation Of Sevelamer Carbonate[fr] Procédé De Préparation De Carbonate De Sevelamer
标题: Processes For The Preparation Of Sevelamer Carbonate[fr] Procédé De Préparation De Carbonate De Sevelamer
摘要:本文描述了制备sevelamer Hydrochloride和sevelamer Carbonate的过程.

专利信息

专利号:US-2017283878-A1
优先权日:2015-12-11
标题:Modulation of globoseries glycosphingolipid synthesis and cancer biomarkers
发明人：WONG CHI-HUEY; WU CHUNG-YI; CHEUNG SARAH K C; CHUANG PO-KAI; HSU TSUI-LING
权利人:ACADEMIA SINICA
摘要:The present disclosure relates to methods and compositions which can modulate the globoseries glycosphingolipid synthesis. Particularly, the present disclosure is directed to glycoenzyme inhibitor compound and compositions and methods of use thereof that can modulate the synthesis of globoseries glycosphingolipid SSEA-3/SSEA-4/GloboH in the biosynthetic pathway; particularly, the glycoenzyme inhibitors target the alpha-4GalT; beta-4GalNAcT-I; or beta-3GalT-V enzymes in the globoseries synthetic pathway. Additionally, the present disclosure is also directed to vaccines, antibodies, and/or immunogenic conjugate compositions targeting the SSEA-3/SSEA-4/GLOBO H associated epitopes (natural and modified) which elicit antibodies and/or binding fragment production useful for modulating the globoseries glycosphingolipid synthesis. Moreover, the present disclosure is also directed to the method of using the compositions described herein for the treatment or detection of hyperproliferative diseases and/or conditions. Furthermore, the instant disclosure also relates to cancer stem cell biomarkers for diagnostic and therapeutic uses.

专利号:CN-102942646-A
优先权日:2012-10-26
标 题 :A kind of synthesis and separation and purification method of high molecular polymer