CAS: 699-12-7; 2-(Phenylthio)Ethanol

该化合物是一种有机化合物,其特征是乙基脊柱上有一个硫醇组(-SH)和一个联苯组;该化合物一般是无色的,可粉黄,具有独特的气味;有机溶剂中溶解,水溶性有限,因其有水分的联苯组,该物质体在水中表现出溶解性;硫醇功能组的存在可产生某种再活动,使其得以参与各种化学反应,例如氧化和替代;2-(苯乙醇)乙醇可用于有机合成,特别是用于制备硫化物和其他含硫化合物;此外,该化合物可能因其潜在的生物活动而在制药业和农化工业中具有应用性;在处理该化合物时,应当采取安全防范措施,因为硫醇可能不易腐坏,如果吸入或浸入,则可能构成健康风险.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

oxirane thiophenol 2-chloro-ethanol (phenylthio)acetic acid 2-chloroethyl phenyl sulfone 2-Chloroethyl phenyl sulfide 2-(phenylsulfonyl)ethanol 1-bromo-2-phenylthioethane

合成工艺路线路线简述

    苯基溴代乙基硫醚置于水体系中,化学反应生成 2-苯硫基乙醇
    参考文献:A Comparison Of The Oxidative Reactivities Of Mustard (2,2'-Dichlorodiethyl Sulfide) And Bivalent Sulfides
    标题:A Comparison Of The Oxidative Reactivities Of Mustard (2,2'-Dichlorodiethyl Sulfide) And Bivalent Sulfides
    摘要:
    DOI:10.1021/jo00298A055

    海关参考信息

    专利信息


    专利号:WO-2017033128-A1
    优先权日:2015-08-25
    标题 :Biphenyl-substitued 4-amino-butyric acid derivatives and their use in the synthesis of nep inhibitors
    发明人:HOOK DAVID; KU JIE; ZHOU JIANGUANG
    权利人:NOVARTIS AG; HOOK DAVID; KU JIE; ZHOU JIANGUANG
    摘要:The invention relates to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, in particular neutral endopeptidase (NEP) inhibitors and prodrugs thereof.

    专利号:US-7429658-B2
    优先权日:2003-09-11
    标题 :Synthesis of protected pyrrolobenzodiazepines
    发明人:HOWARD PHILIP; MASTERSON LUKE
    权利人:SPIROGEN LTD
    摘要:A method of synthesis of a N-10 protected PBD compound of formula (I): n nvia an intermediate of formula (II) or formula (V):

    专利号:US-6492136-B1
    优先权日:1995-12-07
    标题 :Solid phase organic synthesis
    发明人:FLITSCH SABINE LAHJA; TURNER NICHOLAS JOHN
    权利人:GENZYME LTD
    摘要:A method of synthesis of a material corresponding to the general formula:characterized in that it comprises a material corresponding to the following general formula:being cleaved as indicated enzymatically or non-enzymatically using acid catalysis in the presence of a nucleophile, wherein: R1 represents a group providing the site for exo-enzyme or acid hydrolysis; R2 represents an intermediate linked to a solid support; R3 represents a carbohydrate, (oligo-)saccharide, (glyco-)peptide, (glyco-)lipid or an organic molecule which is at least one of heterocyclic and aromatic in structure; X represents O, N(H), N(R''), C(O)O, S, C(O)N(H) or C(O)N(R''), R'' being a non-interfering group; and Support represents a solid support.

    专利号:US-5374743-A
    优先权日:1993-09-30
    标题 :Process for the synthesis of lactide or glycolide from lactic acid or glycolide acid oligomers
    发明人:THAYER CHESTER A; BELLIS HAROLD E
    权利人:DU PONT
    摘要:A process for preparing lactide or glycolide from a lactic acid oligomer or glycolic acid oligomer is disclosed where the molecular weight of the synthesis reactor residue is controlled to no more than 1.2 times that in the feed. The process is carried out at 130° to 280° C. and preferably 180° to 210° C. using from 1 to 6 weight percent catalyst in the oligomer feed to the synthesis reactor. The catalysts are tin or tin compounds, yttrium or rare earth metal compounds, or antimony compounds which are known as alphahydroxycarboxylic acid cyclic dimerization or polymerization catalysts.

    专利号:US-11897853-B2
    优先权日:2018-12-31
    标题 :Synthesis of 1,1,2-trifluoro-4-(substituted sufonyl)-but-1-ene
    发明人:ZELL THOMAS; COHEN SHLOMI
    权利人:ADAMA MAKHTESHIM LTD
    摘要:The present invention provides a process for preparing a compound of formula [I] from a compound of formula [II] using an oxidizing agent and a catalyst, the process is carried out at a low temperature.

    专利号:US-2003138376-A1
    优先权日:2000-03-17
    标题 :Dosing form for reagents, use of said dosing form in organic chemical synthesis and production of said dosing form
    发明人:RUHLAND THOMAS; HOLM PER; SCHULTZ KIRSTEN; HOLM JANNIE EGESKOV; ANDERSEN KIM
    权利人:LUNDBECK & CO AS H
    摘要:A dosing form for at least one solid reagent for use in conventional organic and inorganic synthesis, in parallel synthesis, and in split and mix synthesis in combinatorial chemistry is provided as compressed tablets each containing the same predetermined amount of said at least one reagent embedded in a polymer matrix comprising beads of a polymer insoluble in the solvents for the intended synthesis, which tablets are capable of disintegrating in said solvent for release of the at least one reagent and disperse the matrix as polymer beads into the solvent. The polymer beads forming the matrix and the reagents of the dosing form can easily be removed by filtration in order to separate these from a formed soluble product. n In a method for producing the dosing form, beads of one or more polymers are mixed with the reagents and compressed into tablets after pre-treatment with an aprotic organic solvent.
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    合成参考文献


    摘要:Hollmann, F., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 3, 122.
    摘要:Zhang, C.; Duan, Y.-N., Science of Synthesis: Hypervalent Halogens in Organic Synthesis, (2025) .
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