专利号:US-2024228455-A1 优先权日:2021-04-27 标 题 :Synthesis of cbn and cbnv 发明人:KAVARANA MALCOLM J 权利人:TEEWINOT LIFE SCIENCES CORP 摘要:The invention includes chemical synthesis for preparing cannabinol (CBN) and cannabinovarin (CBNV). The process is suitable for inter alia the large-scale synthesis of pharmaceutical grade CBN and CBNV.
专利号:US-4219489-A 优先权日:1978-09-05 标题:Synthesis of steroids 发明人:BUNES LEONARD A; JOHNSON WILLIAM S 权利人:STANFORD LELAND JUNIOR UNIV TR 摘要:Method and compounds are provided for use in the synthesis of steroids wherein a polyolefin is provided having an initiating group having a chalcogen atom in juxtaposition to a double bond, so as to be capable of bond formation to close to form a ring and having a terminating group involving pi unsaturation (a double or triple bond) conjugated to an aromatic ring. Upon acid catalysis, sigma bonds are formed through the interaction of a carbocation formed at the carbon atom bonded to the chalcogen atom and the double bond intermediate the initiating group and the terminating group, which close to form rings of a steroid nucleus, the carbocation interacting with the pi unsaturation conjugated with the aromatic group and being captured by a nucleophile present in the acidic reaction medium. The resulting steroid product may then be modified in known ways to produce known steroids.
专利号:US-10538790-B2 优先权日:2016-04-04 标题 :Bioenzymatic synthesis of THC-v, CBV and CBN and their use as therapeutic agents 发明人:KAVARANA MALCOLM J; PEET RICHARD C 权利人:TEEWINOT TECH LIMITED 摘要:The present invention provides methods for producing cannabinoids. More specifically, the invention is directed to the bio-enzymatic synthesis of THC-v, CBV and CBN by contacting a compound according to Formula I with a cannabinoid synthase enzyme. Also described is a system for producing these pharmaceutically important cannabinoids and the use of such cannabinoids as therapeutic agents.
专利号:US-6388128-B1 优先权日:1998-10-05 标 题:Stannane synthesis of prostanoids 发明人:CONROW RAYMOND E 权利人:ALCON MFG LTD 摘要:The present invention is directed to novel methods of prostanoid synthesis. Specifically, the invention is directed to the addition of alpha chains to prostanoids using cis-alkenylstannane intermediates.
专利号:US-10669160-B2 优先权日:2018-04-30 标题:Heterogeneous wet synthesis process for preparation of high purity tungsten pentahalide 发明人:LIU YUMIN; LI FENG; WAN ZHIWEN; FAFARD CLAUDIA; WIESE STEFAN; HUSSON GUILLAUME; NIKIFOROV GRIGORY; SUI BIN; GIRARD JEAN-MARC 权利人:AIR LIQUIDE; AIR LIQUIDE AMERICAN 摘要:Synthesis of tungsten pentahalide compositions having low impurity profiles are disclosed. The specific impurity profile permits deposition of high purity tungsten-containing films using vapor deposition processes or other semiconductor manufacturing processes without introduction of performance-impacting contaminants.
专利号:US-2009234121-A1 优先权日:2008-01-16 标 题 :Tridentate (nnc) catalysts for the selective oxidation of hydrocarbons 发明人:PERIANA ROY A; GODDARD III WILLIAM A; OXGAARD JONAS; YOUNG KENNETH 权利人:PERIANA ROY A; GODDARD III WILLIAM A; OXGAARD JONAS; YOUNG KENNETH 摘要:The synthesis of discrete, air, protic, and thermally stable transition metal NNC complexes that catalyze the CH activation and functionalization of alkanes and arenes is disclosed. Methods for the selective conversion of methane to methanol or methyl esters in acidic and neutral media are disclosed.
摘要:Kostikov, R. R.; Khlebnikov, A. F.; Sokolov, V. V., Science of Synthesis, (2010) 47, 773. 摘要:Kostikov, R. R.; Khlebnikov, A. F.; Sokolov, V. V., Science of Synthesis, (2010) 47, 780. 摘要:Zimmer, R.; Trawny, D., Science of Synthesis Knowledge Updates, (2013) 4, 177. 摘要:Matsumoto, K.; Katsuki, T.; Arends, I. W. C. E., Science of Synthesis: Stereoselective Synthesis, (2011) 1, 116. 摘要:Herter, S.; Turner, N. J., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 3, 110.