CAS: 26348-68-5; (S)-Methyl 6-Amino-2-(((Benzyloxy)Carbonyl)Amino)Hexanoate Hydrochloride
该化合物是氨基酸碱的衍生物,氨基氨基磺酸(Z)组受苯氧基碳酸(C)组的保护,而碳酸则转化成甲基酯.该化合物通常用于浸泡合成和作为各种药品生产的中间体.其盐酸形式在水溶液中增加溶解性,使之适合生物应用.Z-Lys-OMeHCl的特点是能够参与混合反应,与其他氨基乙酸或浸泡物碎片发生反应,形成更大的酸.Z组的存在为合成过程中防止不必要的反应提供了保护,以后可通过具体的脱保方法消除这种反应.与许多氨基硫衍生物一样,必须谨慎处理这一化合物,并遵循适当的安全规程,因为它可能表现出刺激性.
- 英文名称(S)-Methyl 6-Amino-2-(((Benzyloxy)Carbonyl)Amino)Hexanoate Hydrochloride
- 中文名称N-苄氧羰基-L-赖氨酸甲酯盐酸盐
- IUPAC名称methyl ((benzyloxy)carbonyl)-L-lysinate hydrochloride
- 其它别名N-苄氧羰基-L-赖氨酸甲酯盐酸盐, >97%; Z-Lys-Ome Hydrochloride
- CAS编号26348-68-5
- MFCD编号:MFCD00077025
- EINECS号:110-502-2
- 分子式:C15H23ClN2O4分子量:330.81
- 产品CID: 1236762
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
物理性质
- 沸点455.3ºC at 760 mmHg
- 闪点229.2ºC
- PSA:90.65
- LogP:2.0052
- 溶解性DMF:30.0(Max Conc. mg/mL);90.0(Max Conc. Mm) DMSO:10.0(Max Conc. mg/mL);30.0(Max Conc. Mm) Ethanol:30.0(Max Conc. mg/mL);90.0(Max Conc. Mm) Pbs (Ph 7.2):10.0(Max Conc. mg/mL);30.0(Max Conc. Mm)
- 外观形态无色至类白色固体
- 储存条件惰性气氛,2-8°C
- 产品应用该化合物是合成中间体,用于合成PEPTIDE 酶基质和碱性表面活性剂,
MSDS等安全信息
欧盟法规
C&L通报上下游产品
methanol 2-[(benzyloxy)carbonyl]-L-lysineN2-[(benzyloxy)carbonyl]-L-lysine α-(benzyloxycarbonyl)-Nε-(tert-butoxycarbonyl)-L-lysine methyl esterNα-(benzyloxycarbonyl)-Nε-(tert-butoxycarbonyl)-L-lysine methyl ester Z-Lys(B°C)-OH (S)-tert-butyl 5-(benzyloxycarbonylamino)-6-hydrazinyl-6-oxohexylcarbamate 2,N6-bis[(1,1-dimethylethoxy)carbonyl]-lysine methyl ester(+)-(S)-N2,N6-bis[(1,1-dimethylethoxy)carbonyl]-lysine methyl ester ε-Acetyl-Nε-hydroxy-Nα-L-lysineNε-Acetyl-Nε-hydroxy-Nα-L-lysine合成工艺路线路线简述
海关参考信息
- 2902300000-甲苯
2905121000-正丙醇
2905130000-正丁醇
2906210000-苄醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-2025151642-A1
优先权日:2024-01-09
标题 :Modified elongation factor p and methods of use thereof
发明人：HECHT SIDNEY; DEDKOVA LARISA; POTUGANTI GAL REDDY; DASKALOVA SASHA
权利人:UNIV ARIZONA STATE
摘要:Provided herein are modified elongation factor P (EF-P) enzymes capable of incorporating noncanonical amino acids during protein synthesis at efficiencies that are different than those of native EF-P. Also provided are methods for preparing and using modified EF-P enzymes.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Tokikawa R, Loffredo C, Uemi M, Machini MT, Bechara EJ. Radical acylation of L-lysine derivatives and L-lysine-containing peptides by peroxynitrite-treated diacetyl and methylglyoxal. Free Radic Res. 2014 Mar;48(3):357-70. doi: 10.3109/10715762.2013.871386. Epub 2014 Jan 7.
合成参考文献
参考文献:10.1007/bf02906202
摘要:Widmer F, Breddam K, Johansen JT. Influence of the structure of amine components on carboxypeptidase Y catalyzed amide bond formation. Carlsberg Research Communications. 1981 Jan;46(1-2):97. doi: 10.1007/bf02906202.
📝 需求与反馈
尽可能描述清楚需求与问题信息
