CAS: 21815-91-8; 3-Chlorobenzo[b]Thiophene-2-Carbonyl Chloride
该化合物是一个多用途的七环建筑块,用于有机合成和制药用途,其活性碳基氯化物组可产生有效的相互碰撞反应,而氯化苯并[b]thiophene核心则为进一步发挥功能提供一个稳定的芳香框架,该化合物因其能够将苯并[b]thiophene mudie引入目标分子,在开发农用化学品,药品和特殊材料方面特别宝贵,因为它具有将苯并[b]thiophene mudie引入目标分子的能力,它具有很高的纯度和一致性,使其适合精确的合成工作流程.
- 英文名称3-Chlorobenzo[b]Thiophene-2-Carbonyl Chloride
- 中文名称3-氯苯并[b]噻吩-2-甲酰氯
- IUPAC名称3-chlorobenzo[b]thiophene-2-carbonyl chloride
- 其它别名2-Chlorocarbonyl-3-Chlorobenzo[b]Thiophene; (2S,4R)-4-Methanesulfonyloxypyrrolidine-1,2-Dicarboxylic Acid 1-T-Butyl Ester 2-Methyl Ester; 3-Chloro-1-Benzothiophene-2-Carbonyl Chloride; 3-Chloro-Benzo[b]Thiophene-2-Car
- CAS编号21815-91-8
- MFCD编号:MFCD00053069
- EINECS号:625-793-6
- 分子式:C9H4Cl2OS分子量:231.09
- 产品CID: 1135830
- 产品分类有机原料→分子砌块→芳杂环类化合物→苯并噻吩类化合物
物理性质
MSDS等安全信息
欧盟法规
ECHA物质C&L通报上下游产品
(E)-3-phenylacrylic acid cis-cinnamic acid (Z)-3-phenylacryloyl chloride Cinnamic acid 4-[(3-chloro-1-benzothiophen-2-yl)carbonyl]morpholine thiophene-2-carboxamide3-chloro-N-(4-pyridyl)benzoβthiophene-2-carboxamide thiophene-2-carboxamide3-chloro-N-(2-pyridyl)benzothiophene-2-carboxamide 3-chlorobenzo[b]thiophene-2-carboxylic acid methyl ester 1,3,5-tris(trichloromethyl)benzene benzene-1,3,5-tricarboxylic acid thionyl chloride 1,3,5-tris(3,5-dimethylpyrazolyl-1-carbonyl)benzene 1,3,5-tricyanobenzene Isophthalaldehyde benzene-1,3,5-tricarboxylic acid trihydrazide合成工艺路线路线简述
📜2-溴-3-苯基丙酸置于氯化亚砜,N-Benzyl-N-Methylmorpholinium Chloride体系中,化学反应 2.5H,以58%的收率获得3-氯苯并ób]噻酚-2-羰酰氯
参考文献:由不饱和化合物的阴离子芳基化产物合成杂环.7.苯并[b]噻吩衍生物的合成中丙烯酸的卤代芳基化反应及其酯
标题:由不饱和化合物的阴离子芳基化产物合成杂环.7.苯并[b]噻吩衍生物的合成中丙烯酸的卤代芳基化反应及其酯
摘要:
Doi:10.1023/a:1026190103546
海关参考信息
- 2902200000-苯
2912110000-甲醛
2903110000-一氯甲烷及氯乙烷 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-5608074-A
优先权日:1993-12-03
标 题:Process for the synthesis of 5-amino tetrazole derivatives
发明人：WALKER JONATHAN
权利人:WARNER LAMBERT CO
摘要:An improved process for the preparation of 3-chlorobenzo[b]thiophene-2-carbonyl chlorides is described where a cinnamic acid is converted in the presence of thionyl chloride and a 4-N,N'-disubstituted aminopyridine in one step to the desired product.
专利号:JP-H09506095-A
优先权日:1993-12-03
标 题 :Improved synthesis of 3-chlorobenzo [b] thiophene-2-carbonyl chloride
专利号:WO-9515323-A1
优先权日:1993-12-03
标 题 :IMPROVED PROCESS FOR THE SYNTHESIS OF 3-CHLOROBENZO[b]THIOPHENE-2-CARBONYL CHLORIDES
专利号:US-5426191-A
优先权日:1993-12-03
标题:Process for the synthesis of 3-chlorobenzo[b]thiophene-2-carbonyl chlorides
专利号:EP-0731800-A1
优先权日:1993-12-03
标题:IMPROVED PROCESS FOR THE SYNTHESIS OF 3-CHLOROBENZO [b]THIOPHENE-2-CARBONYL CHLORIDES
专利号:CA-2172382-A1
优先权日:1993-12-03
标题 :Improved process for the synthesis of 3-chlorobenzo[b]thiophene-2-carbonyl chlorides
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.3184/030823409x466041
摘要:Tarighi S, Abbasi A, Zamanian S, Badiei A, Ghoranneviss M. Crystal structure of 3-chlorobenzo[b]thiophene-2-carbonyl chloride. Journal of Chemical Research. 2009 Jul;2009(7):437–9. doi: 10.3184/030823409x466041.
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