CAS: 1984-58-3; 1,4-Dichloro-2-Methoxybenzene

该化合物是一种氯化芳香化合物,在与氯原子之一相对的正方位上具有甲氧替代物.这种结构具有独特的反应性,使其成为有机合成中有价值的中间体,特别是制药,农用化学品和特殊化学品.电排氯组和对甲基氧合金组创造了平衡的电子配置,有利于选择性替代反应.在标准条件下,其稳定性确保了处理和储存的便利性.该复合物的纯度和定义明确的化学特性使它适合在交叉反应中精确应用,并成为复杂分子框架的构件.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号583-78-8 2,5-二氯苯酚 | CAS号77-78-1 硫酸二甲酯 | CAS号74-88-4 碘甲烷 | CAS号124-41-4 甲醇钠 | CAS号120-82-1 1,2,4-三氯苯 | CAS号1435-50-3 2-溴-1,4-二氯苯 | CAS号348-59-4 2,5-二氯氟苯 | CAS号29682-41-5 1,4-二氯-2-碘苯 | CAS号583-78-8 2,5-二氯苯酚 | CAS号7051-13-0 1-氯-2,4-二甲氧基苯 | CAS号13726-14-2 4-氯-3-甲氧基苯胺 | CAS号150-19-6 3-甲氧基苯酚 | CAS号17801-99-9 1,4-Dichloro-5-... | CAS号60082-97-5 1,2,4-trichloro... | CAS号60082-98-6 1,2,4-trichloro... | CAS号60082-96-4 2',3,4',5',6-pe... | CAS号6130-75-2 2,4,5-三氯苯甲醚 | CAS号55743-73-2 1,4-dichloro-2-...

合成工艺路线路线简述

    📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于copper Chloride体系中,化学反应生成2,5-二氯苯甲醚
    参考文献:Reverdin; Eckhard,Chemische Berichte,1899,Vol. 32,P. 2623
    标题:Reverdin; Eckhard,Chemische Berichte,1899,Vol. 32,P. 2623

    海关参考信息

    专利信息


    专利号:US-10995078-B2
    优先权日:2013-03-13
    标 题:Compounds and compositions for inhibition of FASN
    发明人:BAIR KENNETH W; LANCIA JR DAVID R; LI HONGBIN; LOCH JAMES; LU WEI; MARTIN MATTHEW W; MILLAN DAVID S; SCHILLER SHAWN E R; TEBBE MARK J
    权利人:FORMA THERAPEUTICS INC
    摘要:The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:

    专利号:US-9676721-B2
    优先权日:2010-09-03
    标题 :Compounds and compositions for the inhibition of NAMPT
    发明人:BAIR KENNETH W; BUCKMELTER ALEXANDRE J; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
    权利人:BAIR KENNETH W; BUCKMELTER ALEXANDRE J; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
    摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below.

    专利号:US-9555039-B2
    优先权日:2011-05-09
    标题:Piperidine derivatives and compositions for the inhibition of nicotinamide phosphoribosyltransferase (NAMPT)
    发明人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; KUNTZ JUDITH D; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
    权利人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; KUNTZ JUDITH D; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
    摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below: Formula (I)

    专利号:US-9169209-B2
    优先权日:2011-05-04
    标题:Compounds and compositions for the inhibition of NAMPT
    发明人:BAIR KENNETH W; BAUMEISTER TIMM; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
    权利人:BAIR KENNETH W; BAUMEISTER TIMM; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
    摘要:The present invention relates to compounds and composition for inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below.

    专利号:CN-111822032-A
    优先权日:2020-08-06
    标 题 :Catalyst for synthesizing 2,5-dichlorophenol, in-situ synthesis method of 2,5-dichlorophenol

    专利号:CN-111822032-B
    优先权日:2020-08-06
    标 题 :Catalyst for synthesizing 2,5-dichlorophenol, in-situ synthesis method of 2,5-dichlorophenol

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Jończyk, A.; Kowalkowska, A., Science of Synthesis, (2006) 8, 1069.
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