CAS: 83-15-8; 4-Acetylaminoantipyrine

该化合物是一种有机化合物,其分子式为C10H12N2O2,其特点是存在一个附属于一种抗逆转录酶结构的乙基氨基集团,这助长了其药理特性,该化合物一般是白色的,黄色的晶状固体,在乙醇和丙酮等有机溶剂中可溶解,但在水中的溶解性有限. 4-乙基丙基氨丙基苯主要用于生物化学和药理学领域,经常作为包括光谱测量实验在内的各种分析应用的试剂,其衍生物可能表现出反烟道和厌食活动,使其对药化学具有兴趣,然而,安全数据表明,应谨慎处理,因为它可能对接触健康造成危害.总体而言,4-丙基亚基甲基安基苯丙胺是研究和潜在治疗应用中的宝贵化合物,需要进一步调查其生物影响和行动机制.

结构式图片

物理性质

MSDS等安全信息

上下游产品

4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one acetic anhydride acetic acid acetyl chloride 6H5C3N2(CH3)2ONHC°CH3)2Br3Ho(C6H5C3N2(CH3)2ONHC°CH3)2Br3 6H5C3N2(CH3)2ONHC°CH3)2Cl3Yb(C6H5C3N2(CH3)2ONHC°CH3)2Cl3 6H5C3N2(CH3)2ONHC°CH3)2Cl3Gd(C6H5C3N2(CH3)2ONHC°CH3)2Cl3 6H5C3N2(CH3)2ONHC°CH3)2Cl3Sm(C6H5C3N2(CH3)2ONHC°CH3)2Cl3

合成工艺路线路线简述

  • 22198-72-7 = 83-15-8
    反应条件:1.1 Reagents: Diisopropylethylamine Solvents: Chloroform; Rt; 3 Min,Rt1.2 Catalysts: Nickel Dichloride
    标题:Nmr-Derived Models Of Amidopyrine And Its Metabolites In Complexes With Rabbit Cytochrome P450 2B4 Reveal A Structural Mechanism Of Sequential N-Dealkylation
    作者:Roberts,Arthur G.; Et Al
    参考文献:Biochemistry 日期:2011 卷标:50(12) 页码:2123-2134]

    83-07-8 = 83-15-8
    反应条件:1.1 Solvents: Acetic Anhydride; 1 H,Reflux
    标题:Design And Synthesis Of Some New Thiophene,Thienopyrimidine And Thienothiadiazine Derivatives Of Antipyrine As Potential Antimicrobial Agents
    作者:Aly,Hala M.; Et Al
    参考文献:European Journal Of Medicinal Chemistry 日期:2011 卷标:46(9) 页码:4566-4572]

    37833-20-8 = 83-15-8
    反应条件:1.1 Solvents: Acetic Acid; Reflux
    标题:Studies On New Cyclic Imides Obtained From Aminophenazone With Analgesic Properties: Potent Effects Of A 3,4-Dichloromaleimide Derivative
    作者:De Campos,Fatima; Et Al
    参考文献:Arzneimittel-Forschung 日期:2002 卷标:52(6) 页码:455-461]

    37833-24-2 = 83-15-8 + 75491-63-3
    反应条件:1.1 Solvents: Acetic Acid; Reflux
    标题:Studies On New Cyclic Imides Obtained From Aminophenazone With Analgesic Properties: Potent Effects Of A 3,4-Dichloromaleimide Derivative
    作者:De Campos,Fatima; Et Al
    参考文献:Arzneimittel-Forschung 日期:2002 卷标:52(6) 页码:455-461]

    58-15-1 + 108-30-5 = 83-15-8 + 75491-63-3
    反应条件:1.1 Solvents: Diethyl Ether; Rt2.1 Solvents: Acetic Acid; Reflux
    标题:Studies On New Cyclic Imides Obtained From Aminophenazone With Analgesic Properties: Potent Effects Of A 3,4-Dichloromaleimide Derivative
    作者:De Campos,Fatima; Et Al
    参考文献:Arzneimittel-Forschung 日期:2002 卷标:52(6) 页码:455-461]

    58-15-1 + 108-55-4 = 83-15-8
    反应条件:1.1 Solvents: Diethyl Ether; Rt2.1 Solvents: Acetic Acid; Reflux
    标题:Studies On New Cyclic Imides Obtained From Aminophenazone With Analgesic Properties: Potent Effects Of A 3,4-Dichloromaleimide Derivative
    作者:De Campos,Fatima; Et Al
    参考文献:Arzneimittel-Forschung 日期:2002 卷标:52(6) 页码:455-461]

    83-07-8 = 83-15-8
    反应条件:1.1 Solvents: Dichloromethane; Rt; 1 H,Rt
    标题:Ru-Catalyzed C(Sp2)-H Bond Arylation Of Benzamides Bearing A Novel 4-Aminoantipyrine As A Directing Group
    作者:Al Mamari,Hamad H.; Et Al
    参考文献:European Journal Of Organic Chemistry 日期:2021 卷标:2021(25) 页码:3598-3603]

    83-07-8 = 83-15-8
    反应条件:1.1 Reagents: Sulfur Trioxide
    标题:Preparation Of Antipyrilamides
    作者:Kravchenya,N. A.
    参考文献:Khimiko-Farmatsevticheskii Zhurnal 日期:1984 卷标:18(10) 页码:1241-2]

    17464-89-0 + 83-07-8 = 83-15-8
    反应条件:1.1 5 Min,Rt
    标题:Tetra(Acetoxymethyl)Glycoluril As An Efficient And Novel Reagent For Acylation Of Amines
    作者:Boudebouz,Imene; Et Al
    参考文献:International Journal Of Chemtech Research 日期:2018 卷标:11(5) 页码:301-315]

    68-89-3 = 83-15-8 [标题:Reaction Conditions
    标题:Simultaneous Determination Of The Main Metabolites Of Dipyrone By High-Pressure Liquid Chromatography
    作者:Damm,D.
    参考文献:Arzneimittel-Forschung 日期:1989 卷标:39(11) 页码:1415-17]

    83-07-8 = 83-15-8
    反应条件:1.1 Reagents: Pyridine; Reflux
    标题:Detailed Investigation Of Anticancer Activity Of Sulfamoyl Benz(Sulfon)Amides And 1H-Pyrazol-4-Yl Benzamides: An Experimental And Computational Study
    作者:Iqbal,Jamshed; Et Al
    参考文献:European Journal Of Pharmacology 日期:2018 卷标:832 页码:11-24]

    5395-50-6 = 83-15-8
    反应条件:1.1 Solvents: Pyridine; 24 H,20 °C2.1 5 Min,Rt
    标题:Tetra(Acetoxymethyl)Glycoluril As An Efficient And Novel Reagent For Acylation Of Amines
    作者:Boudebouz,Imene; Et Al
    参考文献:International Journal Of Chemtech Research 日期:2018 卷标:11(5) 页码:301-315]

    = 83-15-8
    反应条件:1.1 Reagents: Thionyl Chloride; 2 H,Reflux2.1 Reagents: Pyridine; Reflux
    标题:Detailed Investigation Of Anticancer Activity Of Sulfamoyl Benz(Sulfon)Amides And 1H-Pyrazol-4-Yl Benzamides: An Experimental And Computational Study
    作者:Iqbal,Jamshed; Et Al
    参考文献:European Journal Of Pharmacology 日期:2018 卷标:832 页码:11-24]

    496-46-8 = 83-15-8
    反应条件:1.1 Solvents: Water; Ph 10 - 12,50 - 60 °C2.1 Solvents: Pyridine; 24 H,20 °C3.1 5 Min,Rt
    标题:Tetra(Acetoxymethyl)Glycoluril As An Efficient And Novel Reagent For Acylation Of Amines
    作者:Boudebouz,Imene; Et Al
    参考文献:International Journal Of Chemtech Research 日期:2018 卷标:11(5) 页码:301-315]

    10543-60-9 + 83-07-8 = 83-15-8 + 28773-97-9
    反应条件:1.1 60 Min,110 °C
    标题:Mechanochemical Activation Of The Reaction Of Tetraacetylglycoluril With Some Cyclic Primary Amines. Synthesis Of Acetamides
    作者:Bakibaev,A. A.; Et Al
    参考文献:Russian Journal Of Organic Chemistry 日期:2018 卷标:54(4) 页码:668-669
📜1,5-二甲基-4-硝基-2-苯基-1,2-二氢吡唑-3-酮置于溶剂黄146,铂体系中,化学反应生成 4-乙酰氨基安替比林
参考文献:Waser,Helvetica Chimica Acta,1925,Vol. 8,P. 124
标题:Waser,Helvetica Chimica Acta,1925,Vol. 8,P. 124

海关参考信息

专利信息


专利号:US-11078093-B2
优先权日:2017-06-30
标 题 :Surfactant-assisted synthesis of surface-functionalized nanoparticle-polymer electrospun composites
发明人：CWIERTNY DAVID; MYUNG NOSANG; PETER KATHERINE T; PARKIN GENE FRANCIS
权利人:UNIV CALIFORNIA; UNIV IOWA RES FOUND
摘要:A method is disclosed for synthesizing nanofilters for water treatment. The method includes: dispersing an active binding agent in an organic solvent solution to create a suspension of the active binding agent and the solution of the solvent; dissolving an organic polymer resin and an anionic surfactant in the suspension of the active binding agent and the solvent solution to create a sol gel; and electrospinning the sol gel to form electrospun nanofiber composites with embedded, surface-active nanoparticles.

专利号:US-2019002309-A1
优先权日:2017-06-30
标 题 :Surfactant-assisted synthesis of surface-functionalized nanoparticle-polymer electrospun composites

其他信息查阅

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

实用工具

⚠️全国化工行业净网倡议书
📋制造商识别码
📖 海关编码查询
📝MSDS生成器

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

参考标题:Mechanochemical Activation Of The Reaction Of Tetraacetylglycoluril With Some Cyclic Primary Amines. Synthesis Of Acetamides
作者:A. A. Bakibaev,N. F. Khoang,V. V. Mamontov |发布日期:2018.4
摘要:A New Mechanochemical Method Has Been Proposed For The Synthesis Of Some Acetamides Containing A Cyclic Fragment By Reaction Of Primary Cyclic Amines With Tetraacetylglycoluril.

合成参考文献


摘要:S61 | UJICCSLIB | Collision Cross Section (CCS) Library from UJI | DOI:10.5281/zenodo.3549476
摘要:S113 | SWISSPHARMA24 | 2024 Swiss Pharmaceutical List with Metabolites | DOI:10.5281/zenodo.10501043
摘要:S66 | EAWAGTPS | Parent-Transformation Product Pairs from Eawag | DOI:10.5281/zenodo.3754448
📝 需求与反馈
尽可能描述清楚需求与问题信息
×

通知