专利号:US-7365197-B2 优先权日:2000-12-29 标题 :Method for the regioselective preparation of substituted benzo[g]quinoline-3-carbonitriles and benzo[g]quinazolines 发明人:BERGER DAN MAARTEN; BIRNBERG GARY HAROLD; WANG YANONG 权利人:WYETH CORP 摘要:This invention relates to a method for the regioselective synthesis of 4,6,7,8-substituted benzo[g]quinoline-3-carbonitriles and 4,6,7,8-substituted benzo[g]quinazolines as well as intermediates thereof. The compounds derived from this invention are useful for the treatment of a variety of diseases that are a result of deregulation of these PTK's, and more specifically, are anti-cancer agents and are useful for the treatment of cancer in mammals. In addition, the compounds derived from this invention are useful for the treatment of polycystic kidney disease in mammals.
专利号:WO-9742158-A1 优先权日:1996-05-03 标题 :Synthesis of a substituted cyclopentadiene compound
专利号:US-4243606-A 优先权日:1976-10-12 标 题 :N-Substituted anilines 发明人:BOURDAUDUCQ PAUL M C; BROUARD CLAUDE M H E; MOEREL CLAUDE L E; STIOT JEAN-PIERRE H 权利人:UGINE KUHLMANN 摘要:The present invention relates to new N-substituted anilines which correspond to the general formula: ##STR1## in which R 1 represents an alkyl radical or substituted alkyl radical, R 2 represents a hydrogen atom, an alkyl radical or substituted alkyl radical, R 3 represents a cyano, carbamoyl, carboxy or carbalkoxy radical and R 4 represents a hydrogen or halogen atom or an alkyl or alkoxy radical. These compounds are valuable intermediates for the preparation of coloring materials, especially as coupling compounds for the synthesis of azo dyes.
专利号:WO-9742157-A1 优先权日:1996-05-03 标 题:Synthesis of an amine-containing cyclopentadiene
专利号:EP-0900192-A1 优先权日:1996-05-03 标题 :Synthesis of an amine-containing cyclopentadiene
专利号:JP-2000509708-A 优先权日:1996-05-03 标题 :Synthesis of amine-containing cyclopentadiene
[参考文献]: Sille Ehala, Et Al. Separation Of Aromatic Hydrophobic Sulfonates By Micellar Electrokinetic Chromatography. J Chromatogr A. 2007 Aug 17;1161(1-2):322-6.