CAS: 76472-88-3; Morachalcone A
该化合物是被归类为一种酸盐的天然化合物,是一种类的氟氯素,主要来自莫瑞萨亚植物,特别是原质的植物.该化合物的特征是黄色晶状晶状外观,展示了一系列生物活动,包括抗氧化剂,抗炎和潜在的抗癌特性.摩拉恰松 A 因其调节各种细胞路径的能力而进行了研究,使其对药理学研究感兴趣.其化学结构具有典型的铬骨干特征,由三碳,不饱和碳基系统连接的两只芳香环组成.这一结构模型对于其生物活动至关重要,因为它能够与各种生物目标相互作用.此外,摩拉恰康A的溶解性和稳定性可能因溶剂和环境条件而不同,而这些条件是研究及潜在治疗用途中考虑的重要因素.
- 英文名称Morachalcone A
- 中文名称摩查尔酮A
- IUPAC名称(E)-1-(2,4-dihydroxy-3-(3-methylbut-2-en-1-yl)phenyl)-3-(2,4-dihydroxyphenyl)prop-2-en-1-one
- 其它别名Morachalcone A; (2E)-1-[2,4-Dihydroxy-3-(3-Methyl-2-Buten-1-yl)Phenyl]-3-(2,4-Dihydroxyphenyl)-2-Propen-1-One; 2-Propen-1-One, 1-[2,4-Dihydroxy-3-(3-Methyl-2-Buten-1-yl)Phenyl]-3-(2,4-Dihydroxyphenyl)-, (2E)-
- CAS编号76472-88-3
- MFCD编号:MFCD20274600
- FDA UNII编号:KRR4CUV7BP
- 分子式:C20H20O5分子量:340.38
- 产品CID: 1756956
- 产品分类天然产物 → 查尔酮类化合物
物理性质
上下游产品
(2E)-3-[2',4'-bis(methoxymethoxy)phenyl]-1-(2-hydroxy-3-(3-methylbut-2-en-1-yl)-4-{[2-(trimethylsilyl)ethoxy]methoxy}phenyl)prop-2-en-1-one 2',4'-dihydroxy-4-acetophenone 2,4-bis(methoxymethoxy)benzaldehyde 2,4-Dihydroxybenzaldehyde合成工艺路线路线简述
📜(E)-3-[2,4-Bis(Methoxymethoxy)Phenyl]-1-[2-Hydroxy-4-(2-Trimethylsilylethoxymethoxy)Phenyl]Prop-2-En-1-One置于盐酸,Florisil,Potassium Carbonate体系中,用 四氢呋喃,异丙醇,丙酮,甲苯 作为反应溶剂,化学反应 44.0H,反应生成 摩查尔酮a
参考文献:A Short Synthesis Of Morachalcone A
标题:A Short Synthesis Of Morachalcone A
摘要:Advanced C-Prenylated Intermediates For Three Aromatase Inhibitors,Including Morachalcone A,Can Be Synthesized Through A Claisen-Schmidt Condensation Followed By Florisil((R))-Catalyzed [1,3]-Sigma Tropic Rearrangement Of A Prenyl Phenyl Ether. (C) 2005 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Tetlet.2005.01.174
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专利信息
专利号:CN-113564140-A
优先权日:2020-04-28
标 题:Three FAD-dependent enzymes in mulberry and their application in the synthesis of Diels-Alder adducts
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主要参考文献
参考标题:Molecular Characterization And Phylogenetic Analysis Of Two Novel Regio-Specific Flavonoid Prenyltransferases From Morus Alba And Cudrania Tricuspidata作者:Ruishan Wang,Ridao Chen,Jianhua Li,Xiao Liu,Kebo Xie,Dawei Chen,Yunze Yin,Xiaoyu Tao,Dan Xie,Jianhua Zou,Lin Yang,Jungui Dai |发布日期:2014.12
摘要:Distributed In Several Plant Families. The Prenylation Catalyzed By Prenyltransferases Represents A Friedel-Crafts Alkylation Of The Flavonoid Skeleton In The Biosynthesis Of Natural Prenylated Flavonoids And Contributes To The Structural Diversity And Biological Activities Of These Compounds. To Date, All Identified Plant Flavonoid Prenyltransferases (Fpts) Have Been Identified In Leguminosae. In The
合成参考文献
参考文献:10.1016/j.bmc.2009.11.027
摘要:Kuroda M, Mimaki Y, Honda S, Tanaka H, Yokota S, Mae T. Phenolics from Glycyrrhiza glabra roots and their PPAR-gamma ligand-binding activity. Bioorg Med Chem. 2010 Jan 15;18(2):962–70. doi: 10.1016/j.bmc.2009.11.027.
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