CAS: 625-56-9; Chloromethyl Acetate

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61644-18-6 33657-49-7 96-35-5

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CAS号50-00-0 甲醛 | CAS号75-36-5 乙酰氯 | CAS号79-20-9 乙酸甲酯 | CAS号57440-43-4 (4-chlorophenyl... | CAS号110-88-3 三聚甲醛 | CAS号64-19-7 冰醋酸 | CAS号7782-50-5 氯气 | CAS号91-78-1 六氢三苯三氰 | CAS号60-35-5 乙酰胺 | CAS号29098-19-9 acetyloxymethyl... | CAS号628-51-3 亚甲基双乙酸酯 | CAS号733-07-3 二荚基甲烷 | CAS号103-84-4 N-乙酰苯胺 | CAS号122-79-2 乙酸苯酯 | CAS号101-61-1 4,4'-四甲基二氨基二苯甲烷 | CAS号109-87-5 甲缩醛 | CAS号79-20-9 乙酸甲酯

📜乙酰氯置于聚合甲醛,Zinc(II) Chloride体系中,化学反应 19.0H,以94%的收率获得产物乙酸氯甲酯
参考文献:Prodrugs Of Nh-Acidic Compounds
标题:Prodrugs Of Nh-Acidic Compounds
摘要:该发明提供了一种持续释放内酰胺,亚酰胺,酰胺,磺胺,氨基甲酸酯或尿素含有母体药物的方法,通过向患者施用本发明的一种前药化合物的有效量,在患者体内,从前药中释放母体药物是持续释放的.适用于本发明方法的前药化合物是母体药物的不稳定结合物,通过羰基连接的前药基团进行衍生化.本发明的前药化合物可用于治疗任何需要内酰胺,亚酰胺,酰胺,磺胺,氨基甲酸酯或尿素含有母体药物作为治疗的情况.

专利信息

专利号:US-2014336369-A1
优先权日:2011-06-28
标题:Process for preparing heparinoids and intermediates useful in the synthesis thereof
发明人：KOVI RAVISHANKER; NAIK ASHISH; PATEL BRIJESH; MADALA MURALIKRISHNA
权利人:APICORE US LLC
摘要:Processes are disclosed for the synthesis of the Factor Xa anticoagulant fondaparinux and related compounds. Protected pentasaccharide intermediates and efficient and scalable processes for the industrial scale production of fondaparinux sodium by conversion of the protected pentasaccharide intermediates via a sequence of deprotection and sulfonation reactions are provided.

专利号:US-9963472-B2
优先权日:2013-11-04
标 题 :Stable pantetheine derivatives for the treatment of pantothenate kinase associated neurodegeneration (PKAN) and methods for the synthesis of such compounds
发明人：JENKO BRANKO; KOSEC GREGOR; PETKOVIC HRVOJE; PODGORSEK BERKE AJDA; PAHOR JERCA; CUSAK ALEN; SIBON ODA CORNELIA MARIA; SRINIVASAN BALAJI
权利人:ACIES BIO D O O; UNIV GRONINGEN; ACADEMISCH ZIEKENHUIS GRONINGEN
摘要:The invention relates to (S)-acyl-4′-phosphopantetheine derivatives, methods of their synthesis, and related medical uses of such compounds. Preferred medical uses relate to the treatment of neurodegenerative diseases, such as PKAN.

专利号:US-4171439-A
优先权日:1975-04-11
标 题 :Antibacterial analogs of isocephalosporins
发明人：CONWAY TERRY T; LIM GARY M F; MENARD MARCEL
权利人:BRISTOL MYERS CO
摘要:There is described the stereoselective total synthesis of novel DELTA 2,3-1,4-morpholine-2-carboxylic acids possessing a fused beta -lactam ring in the 1,6-position and carrying a substituent cis to carbon 5 in the 7-position of the fused ring system represented by the general formula I wherein Z is halo or hydroxyl and X is acylamino. Also included in the invention are compounds of the above formula in which the carboxyl group at the 2-position is protected as by an easily cleavable ester group and salts of both the free acids and carboxyl-protected compounds. The compounds are potent antibacterial agents.

专利号:US-9296709-B2
优先权日:2012-07-03
标 题 :Manufacture of 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid
发明人：GUNIC ESMIR; GALVIN GABRIEL
权利人:ARDEA BIOSCIENCES INC
摘要:Described herein are certain processes for the synthesis of compounds of Formula (I):

专利号:US-9907796-B2
优先权日:2012-10-04
标题:Methods of treating tumoral diseases, or bacterial or viral infections
发明人：DEOKAR RHUSHIKESH CHANDRABHAN; DUGAR SUNDEEP; MAHAJAN DINESH; WERNER MILTON HENRY
权利人:DEOKAR RHUSHIKESH CHANDRABHAN; DUGAR SUNDEEP; MAHAJAN DINESH; WERNER MILTON HENRY; INHIBIKASE THERAPEUTICS INC
摘要:Novel compounds and their synthesis are described. Methods for using these compounds in the prevention or treatment of cancer, a bacterial infection or a viral infection in a subject are also described.

专利号:US-2018118767-A1
优先权日:2013-11-04
标题 :Stable pantetheine derivatives for the treatment of pantothenate kinase associated neurodegeneration (pkan) and methods for the synthesis of such compounds