CAS: 25236-64-0; 2,2,2-Trifluoroethyl Methanesulfonate

相似化合物

163035-65-2 6226-25-1 74427-22-8

上下游产品

CAS号75-89-8 三氟乙醇 | CAS号124-63-0 甲基磺酰氯 | CAS号338741-98-3 (Z)-2-methyl-N-... | CAS号106854-77-7 1-溴-4-(2,2,2-三氟... | CAS号62158-88-7 1-methoxy-4-(2,... | CAS号19013-30-0 4-甲氧基苯基甲磺酸 | CAS号115-10-6 二甲醚 | CAS号103-50-4 二苄醚 | CAS号67696-28-0 2,2,2-trifluoro... | CAS号77745-03-0 苄基(2,2,2-三氟乙烷基)硫烷 | CAS号766-92-7 苄基甲基硫醚 | CAS号57946-61-9 4-(2,2,2-三氟乙氧基)苯胺 | CAS号160969-02-8 2-[2-(2,2,2-tri...

2,2,2-三氟乙醇,甲基磺酰氯置于sodium Carbonate体系中,化学反应 22.0H,以91%的收率获得2,2,2-三氟乙基甲磺酸酯
参考文献:磺酰卤和酯的烯烃化:霍金斯反应的范围,局限性和机理研究
标题:磺酰卤和酯的烯烃化:霍金斯反应的范围,局限性和机理研究
摘要:链烷磺酰基卤化物和酯的碳负离子与不可烯化的羰基化合物反应生成烯烃.机理研究表明,最初的碳氢化合物以醛醇缩合形式加成环基后再裂解成烯烃,而磺酰基部分上的离去基团(rso 2 X)控制着碳负离子的稳定性和烯烃形成的速率.
Doi:10.1021/acs.Orglett.7B00517

专利信息

专利号:WO-2011101864-A1
优先权日:2010-02-17
标题 :Novel process for the synthesis of phenoxyethyl derivatives
发明人：JAIN RAJESH; JAGDEESHWAR RAO R; MAHENDER RAO SIRIPRAGADA
权利人:PANACEA BIOTEC LTD; JAIN RAJESH; JAGDEESHWAR RAO R; MAHENDER RAO SIRIPRAGADA
摘要:The present invention provides an improved process for the synthesis of 2-[2- (2,2,2-trifluoroethoxy)phenoxy]ethanol intermediate, its derivatives and/or its pharmaceutically acceptable salts, useful in the synthesis of α-1 adrenoceptor blockers such as silodosin.

专利号:CN-105237340-A
优先权日:2015-05-29
标 题 :A new method for the synthesis of 4,4,4-trifluorobutanol

专利号:US-4968829-A
优先权日:1984-07-18
标 题 :Novel substituted aromatic compounds
发明人：HENRICK CLIVE A
权利人:SANDOZ LTD
摘要:Substituted phenoxy, phenylthio and anilino compounds, intermediates therefor, synthesis thereof, and their use for the control of pests.

专利号:US-2010280024-A1
优先权日:2007-10-15
标 题:Renin inhibitors
发明人：DESAI JIGAR; THOMBARE PRAVIN S; JAIN MUKUL R; PATEL PANKAJ RAMANBHAI
权利人:DESAI JIGAR; THOMBARE PRAVIN S; JAIN MUKUL R; PATEL PANKAJ RAMANBHAI
摘要:The present invention relates to renin inhibitors of formula (I), their pharmaceutically acceptable salts and pharmaceutical compositions containing them. The present invention also relates to a process of preparing compounds of general formula (I), their tautomeric forms, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and novel intermediates involved in their synthesis.

专利号:US-5037991-A
优先权日:1984-07-18
标题:Novel substituted aromatic compounds
发明人：HENRICK CLIVE A
权利人:SANDOZ LTD
摘要:Substituted phenoxy, phenylthio and anilino compounds, intermediates therefor, synthesis thereof, and their use for the control of pests.