CAS: 187589-36-2; Piperazine-2-Carbonitrile

相似化合物

187589-35-1 1053656-76-0 859518-35-7

上下游产品

2-Chloroacrylonitrile ethylenediamine tert-butyl 3-cyanopiperazine-1-carboxylate 4-benzyl-2-piperazinecarbonitrile tert-butyl 3-cyanopiperazine-1-carboxylate

📜2-氯丙烯腈置于乙二胺体系中,用 四氢呋喃 用作溶剂,化学反应生成2-氰基哌嗪
参考文献:2-Cyanopiperazine And Method Of Producing The Same
标题:2-Cyanopiperazine And Method Of Producing The Same
摘要:2-氰基哌嗪由以下化学式(1)代表:##str1##或其盐.2-氰基哌嗪可通过将2-卤代丙烯腈与乙二胺反应或将2,3-二卤代丙烯腈与乙二胺反应而制得.2-氰基哌嗪可用作药物,农药等的中间体,并且可使用2-氰基哌嗪轻松制备出对光学活性的n-叔丁基-2-哌嗪羧酰胺,后者在制备hiv蛋白酶抑制剂洛匹那韦的中间体时非常有用.

专利信息

专利号:US-9304126-B2
优先权日:2012-08-21
标题:Haptens of quetiapine
发明人：DONAHUE MATTHEW GARRETT; GONG YONG; SALTER RHYS; HRYHORENKO ERIC; DECORY THOMAS R; REMMERIE BART; SANKARAN BANUMATHI
权利人:JANSSEN PHARMACEUTICA NV; ORTHO CLINICAL DIAGNOSTICS INC
摘要:The invention relates to compounds of Formula I, wherein R 1 , R 2 , and R 3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from quetiapine. The invention also relates to conjugates of a quetiapine hapten and a protein.

专利号:DE-69604247-T2
优先权日:1995-07-19
标 题:2-cyanopiperazine and its use for the synthesis of biologically active substances

专利号:EP-0754686-B1
优先权日:1995-07-19
标 题 :2-cyanopiperazine and use thereof for the synthesis of biologically active substances

专利号:DE-69604247-D1
优先权日:1995-07-19
标 题 :2-cyanopiperazine and its use for the synthesis of biologically active substances

专利号:EP-0754686-A1
优先权日:1995-07-19
标题 :2-cyanopiperazine and use thereof for the synthesis of biologically active substances