CAS: 1628530-41-5; N-(4-((6,7-Dimethoxyquinolin-4-yl)Oxy)Phenyl)-N-(4-Fluoro-3-Hydroxyphenyl)Cyclopropane-1,1-Dicarboxamide

• 英文名称N-(4-((6,7-Dimethoxyquinolin-4-yl)Oxy)Phenyl)-N-(4-Fluoro-3-Hydroxyphenyl)Cyclopropane-1,1-Dicarboxamide
• 中文名称N-(4-((6,7-二甲氧基喹啉-4-基)氧基)苯基)-N-(4-氟-3-羟基苯基)环丙烷-1,1-二甲酰胺
• IUPAC名称N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluoro-3-hydroxyphenyl)cyclopropane-1,1-dicarboxamide
• 其它别名N-[4-[(6,7-Dimethoxy-4-Quinolinyl)Oxy]Phenyl]-N'-(4-Fluoro-3-Hydroxyphenyl)-1,1-Cyclopropanedicarboxamide; Cabozantinib Impurity 66; 1,1-Cyclopropanedicarboxamide, N-[4-[(6,7-Dimethoxy-4-Quinolinyl)Oxy]Phenyl]-N'-(4-Fluoro-3-Hydroxyphenyl)-; N-(4-((6,7-Dimethoxyquinolin-4-Yl)Oxy)Phenyl)-N-(4-Fluoro-3-Hydroxyphenyl)Cyclopropane-1,1-Dicarboxamide; Cabozantinib Impurity 79; Tributyl Acetylcitrate Impurity 2 (Tributyl Acetylcitrate Ep Impurity B); N-(4-((6,7-Dimethoxyquinolin-4-Yl)Oxy)Phenyl)-N-(4-Fluoro-3-Hydroxyphenyl)Cyclopropane-1,1-Dicarboxamide (Cabozantinib Impurity）
• CAS编号1628530-41-5
• MFCD编号:MFCD34473109
• FDA UNII编号:F5HE6AB5AL
• 分子式:C28H24FN3O6分子量:517.51
• 产品CID: 824664
• 产品分类Chemistry → Organic Building Blocks → Ethers | Quinolines

• 相似结构搜索
• InChIKey: ACPMVTQPBYQJIM-UHFFFAOYSA-N
• InChI=1S/C28H24FN3O6/c1-36-24-14-19-21(15-25(24)37-2)30-12-9-23(19)38-18-6-3-16(4-7-18)31-26(34)28(10-11-28)27(35)32-17-5-8-20(29)22(33)13-17/h3-9,12-15,33H,10-11H2,1-2H3
• 计算化学: 氢键受体数8.0氢键供体数3.0可旋转键数8.0

物理性质

• 沸点788.4±60.0 °C(预测)
• 密度1.447±0.06 g/cm3(预测)
• pKa:8.31±0.10(预测)
• LogP:5

MSDS等安全信息

• 警示词Warning
• 危险描述H302-H315-H319-H335-
• 防范说明P261-P264-P270-P271-P280-P301+P312-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501-

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  2907210001-间苯二酚
  2912110000-甲醛
  2912120000-乙醛
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