📜2-萘硫醇置于ammonium Hydroxide,Manganese(Iv) Oxide,氧气体系中,用 水,N,N-二甲基甲酰胺 用作溶剂,90.0 °C,1.0 Mpa 条件下,反应 40.0H,以41%的收率获得萘-2-磺酰胺 参考文献:One-Pot Aerobic Oxidative Sulfonamidation Of Aromatic Thiols With Ammonia By A Dual-Functional β-Mno2 Nanocatalyst 标题:One-Pot Aerobic Oxidative Sulfonamidation Of Aromatic Thiols With Ammonia By A Dual-Functional β-Mno2 Nanocatalyst 摘要:高比表面积的β-Mno2纳米颗粒在使用o2和nh3进行一锅式氧化磺酰胺化反应中表现出很高的活性. Doi:10.1039/c9Cc09411C
专利号:US-9221829-B2 优先权日:2011-09-14 标题:Synthesis of triazolopyrimidine compounds 发明人:MARAS NENED; ZUPANCIC BORUT 权利人:MARAS NENED; ZUPANCIC BORUT; LEK PHARMACEUTICALS 摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives, suitable for the preparation of Ticagrelor (TCG).
专利号:EP-2570405-A1 优先权日:2011-09-14 标题:Synthesis of Triazolopyrimidine Compounds 权利人:LEK PHARMACEUTICALS 摘要:The present invention relates to the filed of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives, suitable for the preparation of ticagrelor (TGC)
专利号:US-9428524-B2 优先权日:2010-05-25 标 题:Synthetic process for the manufacture of ecteinascidin compounds 发明人:MARTIN LÓPEZ MA JESÚS; FRANCESCH SOLLOSO ANDRÉS; CUEVAS MARCHANTE MARIA DEL CARMEN 权利人:MARTIN LÓPEZ MA JESÚS; FRANCESCH SOLLOSO ANDRÉS; CUEVAS MARCHANTE MARIA DEL CARMEN; PHARMA MAR SA 摘要:This invention relates to compounds of formula II: wherein R 1 , R 2 , Prot SH , and Prot NH are as defined, to processes for the synthesis of ecteinascidins of formula I from compounds of formula II, and to processes for the synthesis of compounds of formula II.
专利号:US-2022411449-A1 优先权日:2019-11-13 标 题 :Method for Preparing Heteroleptic Triarylbismuthanes and Compounds Produced by the Same 发明人:HYVL JAKUB; LEHRER AXEL 权利人:UNIV HAWAII 摘要:A method for controlling dismutation in the synthesis of a heteroleptic triarylbismuthane is provided as are compounds produced by such a method and use of the same to inhibit the replication of microorganisms.
专利号:US-7420070-B2 优先权日:2000-12-28 标 题:Process for preparing optically active 2,3-dihydrobenzofuran compounds 发明人:AOKI ISAO; ADACHI MARI; TAWADA HIROYUKI; YAMASHITA MAKOTO; SERA MISAYO 权利人:TAKODA PHARMACEUTICAL COMPANY 摘要:A process for preparing optically active 2,3-dihydrobenzofuran compounds which comprises subjecting a 2,3-dihydrobenzofuran compound represented by the general formula or a salt thereof to optical resolution with an optically active acid compound: n n[wherein R 1 and R 2 are each hydrogen or an optionally substituted hydrocarbon group; R 3 is an optionally substituted aromatic group; and C is a benzene ring which may further have a substituent in addition to the amino group]. The process enables industrially advantageous production of intermediates for the synthesis of optically active 2,3-dihydrobenzofuran compounds useful as preventive and/or therapeutic drugs for neurodegenerative diseases and so on.
专利号:CA-2848621-C 优先权日:2011-09-14 标题 :Synthesis of triazolopyrimidine compounds
参考标题:A General Iodine-Mediated Synthesis Of Primary Sulfonamides From Thiols And Aqueous Ammonia 作者:Jian-Bo Feng,Xiao-Feng Wu 摘要:A General And Efficient Methodology For Preparing Primary Sulfonamides Has Been Developed. In The Presence Of Iodine As The Catalyst And Tbhp (70% In Water) As The Oxidant, A Wide Range Of Primary Sulfonamides Were Prepared From The Corresponding Thiols And Aqueous Ammonia In Moderate To Good Yields.
合成参考文献
摘要:Duan, J.; Chen, H.; Hong, X.; Harmata, M., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 255.