CAS: 1576-47-2; Naphthalene-2-Sulfonamide

该化合物是一种有机化合物,其特点是存在一个环状氯化萘,以磺酰胺组为替代品,该化合物一般是白色的,白色的晶状固体,以其在水中的溶解性较低而闻名,同时在有机溶剂中更容易溶解.纳phethalene-2-硫酰胺的特性使其在各种应用中有用,包括作为有机合成的试剂和染料和药品生产中的中间体.磺酰胺功能组传播某些生物活动,可在药用化学中加以利用.此外,由于氯化萘衍生物独特的电子特性,常常对其在材料科学方面的潜力进行研究.在处理该化合物时应考虑到安全因素,因为如果吸入或摄入,可能会对健康造成危害.

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相似化合物

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合成工艺路线路线简述

  • 合成目标产物 Naphthalene-2-Sulfonamide 主要起始原料 Naphthalene-2-Sulfonic Acid
  • (文献来源)合成步骤主要原料 Naphthalene-2-Sulfonic Acid
📜2-萘硫醇置于ammonium Hydroxide,Manganese(Iv) Oxide,氧气体系中,用 水,N,N-二甲基甲酰胺 用作溶剂,90.0 °C,1.0 Mpa 条件下,反应 40.0H,以41%的收率获得萘-2-磺酰胺
参考文献:One-Pot Aerobic Oxidative Sulfonamidation Of Aromatic Thiols With Ammonia By A Dual-Functional β-Mno2 Nanocatalyst
标题:One-Pot Aerobic Oxidative Sulfonamidation Of Aromatic Thiols With Ammonia By A Dual-Functional β-Mno2 Nanocatalyst
摘要:高比表面积的β-Mno2纳米颗粒在使用o2和nh3进行一锅式氧化磺酰胺化反应中表现出很高的活性.
Doi:10.1039/c9Cc09411C

海关参考信息

专利信息


专利号:US-9221829-B2
优先权日:2011-09-14
标题:Synthesis of triazolopyrimidine compounds
发明人:MARAS NENED; ZUPANCIC BORUT
权利人:MARAS NENED; ZUPANCIC BORUT; LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives, suitable for the preparation of Ticagrelor (TCG).

专利号:EP-2570405-A1
优先权日:2011-09-14
标题:Synthesis of Triazolopyrimidine Compounds
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the filed of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives, suitable for the preparation of ticagrelor (TGC)

专利号:US-9428524-B2
优先权日:2010-05-25
标 题:Synthetic process for the manufacture of ecteinascidin compounds
发明人:MARTIN LÓPEZ MA JESÚS; FRANCESCH SOLLOSO ANDRÉS; CUEVAS MARCHANTE MARIA DEL CARMEN
权利人:MARTIN LÓPEZ MA JESÚS; FRANCESCH SOLLOSO ANDRÉS; CUEVAS MARCHANTE MARIA DEL CARMEN; PHARMA MAR SA
摘要:This invention relates to compounds of formula II: wherein R 1 , R 2 , Prot SH , and Prot NH are as defined, to processes for the synthesis of ecteinascidins of formula I from compounds of formula II, and to processes for the synthesis of compounds of formula II.

专利号:US-2022411449-A1
优先权日:2019-11-13
标 题 :Method for Preparing Heteroleptic Triarylbismuthanes and Compounds Produced by the Same
发明人:HYVL JAKUB; LEHRER AXEL
权利人:UNIV HAWAII
摘要:A method for controlling dismutation in the synthesis of a heteroleptic triarylbismuthane is provided as are compounds produced by such a method and use of the same to inhibit the replication of microorganisms.

专利号:US-7420070-B2
优先权日:2000-12-28
标 题:Process for preparing optically active 2,3-dihydrobenzofuran compounds
发明人:AOKI ISAO; ADACHI MARI; TAWADA HIROYUKI; YAMASHITA MAKOTO; SERA MISAYO
权利人:TAKODA PHARMACEUTICAL COMPANY
摘要:A process for preparing optically active 2,3-dihydrobenzofuran compounds which comprises subjecting a 2,3-dihydrobenzofuran compound represented by the general formula or a salt thereof to optical resolution with an optically active acid compound: n n[wherein R 1 and R 2 are each hydrogen or an optionally substituted hydrocarbon group; R 3 is an optionally substituted aromatic group; and C is a benzene ring which may further have a substituent in addition to the amino group]. The process enables industrially advantageous production of intermediates for the synthesis of optically active 2,3-dihydrobenzofuran compounds useful as preventive and/or therapeutic drugs for neurodegenerative diseases and so on.

专利号:CA-2848621-C
优先权日:2011-09-14
标题 :Synthesis of triazolopyrimidine compounds

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主要参考文献

参考标题:A General Iodine-Mediated Synthesis Of Primary Sulfonamides From Thiols And Aqueous Ammonia
作者:Jian-Bo Feng,Xiao-Feng Wu
摘要:A General And Efficient Methodology For Preparing Primary Sulfonamides Has Been Developed. In The Presence Of Iodine As The Catalyst And Tbhp (70% In Water) As The Oxidant, A Wide Range Of Primary Sulfonamides Were Prepared From The Corresponding Thiols And Aqueous Ammonia In Moderate To Good Yields.

合成参考文献


摘要:Duan, J.; Chen, H.; Hong, X.; Harmata, M., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 255.
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