CAS: 108-59-8; Dimethylmalonate

相似化合物

16695-14-0 6149-41-3 504-63-2

上下游产品

CAS号96-34-4 氯乙酸甲酯 | CAS号67-56-1 甲醇 | CAS号141-82-2 丙二酸 | CAS号74-87-3 氯甲烷 | CAS号141-95-7 丙二酸钠 | CAS号106-48-9 对氯苯酚 | CAS号16695-14-0 甲基丙二酸氢 | CAS号79-22-1 氯甲酸甲酯 | CAS号201230-82-2 carbon monoxide | CAS号124-41-4 甲醇钠 | CAS号110027-73-1 dimethyl 2-(4-o... | CAS号107428-06-8 2-烯丙基-2-(2-丙炔-1... | CAS号10255-99-9 N,N''-DIBENZYL-... | CAS号111209-96-2 PROPANEDIOIC AC... | CAS号1733-15-9 1,1,2,2-Ethenet... | CAS号28781-91-1 hexamethyl prop... | CAS号110622-29-2 tetramethyl 1-m... | CAS号5464-22-2 四甲基乙烷-1,1,2,2-四羧酸酯 | CAS号29340-86-1 dimethyl 2,2-di... | CAS号121079-95-6 tetramethyl 1-i...

溴丙二酸二甲酯置于3,4,5,6-四-9H-咔唑-9-基-1,2-苯二甲腈,三乙胺体系中,用 N-甲基吡咯烷酮 用作溶剂,化学反应 0.17H,以48%的收率获得丙二酸二甲酯
参考文献:可定制的咔唑基氰基苯基光催化剂,用于可见光诱导的芳基卤化物还原
标题:可定制的咔唑基氰基苯基光催化剂,用于可见光诱导的芳基卤化物还原
摘要:摘要本文设计并合成了一系列具有广泛的光氧化还原能力的咔唑基氰基苯(ccb)基有机光催化剂,从而可以通过无金属过程精确控制光催化反应活性,从而可控制地还原芳基卤化物.筛选出的ccb(5Czbn)是一种无金属,低成本,可扩展且可持续的光催化剂,具有强大的氧化和还原能力,在脱卤和cc键形成的芳基化反应中均表现出优异的性能.
Doi:10.1016/j.Cclet.2019.12.017

专利信息

专利号:US-11479577-B2
优先权日:2016-05-18
标题:Intermediates for the synthesis of bile acid derivatives, in particular of obeticholic acid
发明人：WEYMOUTH-WILSON ALEXANDER; KOMSTA ZOFIA; WALLIS LAURA; EVANS TIMOTHY; DAVIES IEUAN; OTTER CARL; BATCHELOR RHYS
权利人:NZP UK LTD
摘要:The present invention relates to compounds which are intermediates in the synthesis of bile acid derivatives with pharmacological activity. The invention relates to compounds of general formula (I):wherein:, R1, R2, R3, R4, R5, R6 and Y are as defined herein.The compounds are intermediates in the synthesis of synthetic bile acids which are useful in the treatment of conditions such as liver disease. In addition, the invention relates to a method of synthesizing these intermediates and a method of preparing obeticholic acid and obeticholic acid analogues from the compounds of the invention.

专利号:US-11891351-B2
优先权日:2020-03-20
标 题 :Synthesis of capsaicin derivatives
发明人：LAGER ERIK
权利人:AXICHEM AS
摘要:The present invention relates to the synthesis of capsaicin derivatives, specifically to the synthesis of 6-heptyne derivatives of capsaicin.

专利号:US-4288608-A
优先权日:1978-06-01
标题:Synthesis of anthracyclines
发明人：JOHNSON FRANCIS; KIM KYOUNG S
权利人:RESEARCH CORP
摘要:There is provided a novel method of synthesizing certain heterocyclic quinones. In particular there is provided a novel and regiospecific synthesis of 9-acetyl-6,11-dihydroxy-4-methoxy-7,8,9,10-tetrahydronaphthacene-5,12-quinone (7,9-dideoxydaunomycinone) which is known intermediate in the synthesis of daunomycinone. There is also provided a method of preparing analogs of 7,9-dideoxydaunomycinone which thus provide for the preparation of known and desired analogs of daunomycinone. Daunomycinone is a known compound which is an intermediate in the preparation of the clinically accepted naturally-occurring antitumor antibiotics daunomycin and its derivitive adriamycin.

专利号:US-4870199-A
优先权日:1986-04-30
标题 :Processes for the synthesis of diprotected R[R*,S*]-3,5-dihydroxy-6-oxohexanoate esters
发明人：CHEN KAU-MING; HARDTMANN GOETZ E; KAPA PRASAD K; LEE GEORGE T; LINDER JEROME; WATTANASIN SOMPONG
权利人:SANDOZ PHARMACEUTICALS CORP
摘要:Process for the synthesis of compounds of the formula in R[R*,S*] enantiomeric form, wherein each P1 is independently an hydroxy group-protecting group, and R2z is C1-4alkyl, benzyl or allyl, comprising, as a key step when R2z is R2x, the reaction of the compound of the formula in (S) enantiomeric form with a compound of the formula Mg &cir& +2 ((-)OOC-CH2-COOR2x)2 to obtain a compound of the formula in (S) enantiomeric form, and, as a key step when R2z is R2y, the reaction of a compound of the formula in (S) enantioimeric form with a compound of the formula Li(+)(-)CH2-COOR2y to obtain a compound of the formula in (S) enantiomeric form, wherein R2x is primary or secondary C1-4alkyl, benzyl or allyl, R2y is C1-4alkyl not containing an asymmetric carbon atom, and R3' is methyl or ethyl, processes for the synthesis of compounds of the formula comprising reacting a compound of the formula with the reaction product of a strong base and a compound of the formula optionally followed by, when R2z is allyl, cleavage of the allyl and P1 groups to obtain the corresponding compound of the formula wherein each R7 is methyl or ethyl, R is as defined in the specification, and each P1 independently and R2z are as defined above, and the compounds of the formula wherein R and each R7 are as defined above.

专利号:US-5945548-A
优先权日:1995-03-03
标题:Process for the synthesis of α-substituted acrylic acids and their application
发明人：DUHAMEL PIERRE; DUHAMEL LUCETTE; DANVY DENIS; MONTEIL THIERRY; LECOMTE JEANNE-MARIE; SCHWARTZ JEAN-CHARLES
权利人:BIOPROJECT SOC CIV
摘要:Process for the synthesis of α-substituted acrylic acids of general formula (I) and their application to the synthesis of N-(mercaptoacyl)aminoacid derivatives of formula (II). ##STR1##

专利号:US-7122693-B2
优先权日:1988-04-11
标题 :Acetaldehyde acetal compounds, their synthesis, and uses thereof
发明人：BELLEAU EXECUTRIX OF ESTATE PI; DIXIT DILIP M; NGUYEN-BA NGHE
权利人:SHIRE BIOCHEM INC
摘要:The acetaldehyde compounds, 2-thiobenzoylacetaldehyde diethylacetal, 2-benzoyloxyacetaldehyde bis(2-methoxyethyl)acetal, 2-hydroxyacetaldehyde bis( 2-methoxyethyl)acetal, 2-thiobenzoylacetaldehyde bis(2-methoxy-ethyl)acetal, and 2-thioacetaldehyde bis(2-methoxyethyl)acetal, are useful as intermediates in the synthesis of substituted 1,3-oxathiolanes and substituted 1,3-dioxolanes.